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OBJECTIVE: To evaluate the hearing status of growth hormone (GH)-naive adults with isolated GH deficiency (IGHD) belonging to an extended Brazilian kindred with a homozygous mutation in the GH-releasing hormone receptor gene. STUDY DESIGN: Cross-sectional. SETTING: Divisions of Endocrinology and Otorhinolaryngology of the Federal University of Sergipe. SUBJECTS AND METHODS: Twenty-six individuals with IGHD (age, 47.6 ± 15.1 years; 13 women) and 25 controls (age, 46.3 ± 14.3 years; 15 women) were administered a questionnaire on hearing complaints and hearing health history. We performed pure-tone audiometry, logoaudiometry, electroacoustic immittance, and stapedial reflex. To assess outer hair cell function in the cochlea, we completed transient evoked otoacoustic emissions (TEOAEs). To assess the auditory nerve and auditory brainstem, we obtained auditory brainstem responses (ABRs). RESULTS: Misophonia and dizziness complaints were more frequent in those with IGHD than in controls (P = .011). Patients with IGHD had higher thresholds at 250 Hz (P = .005), 500 Hz (P = .006), 3 KHz (P = .008), 4 KHz (P = .038), 6 KHz (P = .008), and 8 KHz (P = .048) and mild high-tones hearing loss (P = .029). Stapedial reflex (P < .001) and TEOAEs (P = .025) were more frequent in controls. There were no differences in ABR latencies. Hearing loss in patients with IGHD occurred earlier than in controls (P < .001). CONCLUSION: Compared with controls of the same area, subjects with untreated, congenital lifetime IGHD report more misophonia and dizziness, have predominance of mild high-tones sensorineural hearing loss, and have an absence of stapedial reflex and TEOAEs.

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Introduction: Septum deviation in children may alter the early physiologic process of breathing, causing obligatory oral breathing and consequently changing craniofacial development and even intellect. Because of these consequences, septoplasty should be performed as early as possible. Materials and Methods: The retrospective study reviewed the results of septoplasty in 40 children under 12 years old who had follow-up after surgery for a maximum period of 7 years. The research was submitted to the ethics committee and approved with protocol number 10331912.0.0000.0058. Results: Forty patients underwent septoplasty, 39 (97.5%) had cauterization of inferior turbinate and associated procedure, 20 (50%) had adenotonsillectomy, and 17 (42.5%) had adenoidectomy. Conclusion: Nasal septum deviation should be corrected early to provide the harmonious growth of the face and to enable normal development of the child, without the occurrence of nasal deformity.

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Objetivo: Apresentar nossa experiência em dacriocistorrinostomia endoscópica, discutindo os resultados com os encontrados na literatura. Métodos: O material desse estudo consistiu de 16 dacricistorrinostomias realizadas em 12 pacientes acompanhados no período de 2009 a 2011. Analisamos sexo, idade no momento da cirurgia, etiologia da dacriocistite, quadro clínico, número de cirurgias necessárias para a correção, seguimento pós-operatório. Resultados: Houve predomínio do sexo feminino em relação ao masculino (5:1) com idades entre 8 e 71 anos, com média de 35,2 anos. Com relação à etiologia, oito foram classificados como idiopáticos; três, pós-traumáticos e um iatrogênico. Os pacientes foram acompanhados em média durante o período de seis meses, com melhora dos sintomas. Apenas dois pacientes evoluíram com permanência de epífora, sendo um deles reoperado com êxito por via externa. Conclusão:A cirurgia endoscópica endonasal deve ser considerada nos pacientes com obstrução das vias lacrimais, devido ao seu alto índice de sucesso, além de ser um procedimento seguro, com menor morbidade e proporcionar melhor resultado estético.

Objective:To present our experience in endoscopic dacryocystorhinostomy, discussing the results with those found in the literature. Methods: The material in this study consisted of sixteen surgeries performed in twelve patients followed between 2009 to 2011. We analyzed gender, age at surgery, etiology of dacryocystitis, clinical features, number of surgeries required to repair, follow-up. Results: There was a predominance of females compared to males (5:1) aged between 8 and 71 years, mean35.2 years. With regard to etiology, eight were classified as idiopathic, three, posttraumatic, and one, iatrogenic. Patients were followed on average over the period of six months, with improvement of symptoms. Only two patients had persistence of epiphora, one being reoperated successfully by external approach. Conclusion: Endoscopic endonasal surgery should be considered in patients with lacrimal obstruction, due to its high success rate, besides being safe procedure with less morbidity and give better cosmetic results.

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Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and histologically benign tumor, generally observed in male adolescents. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. Juvenile nasopharyngeal angiofibroma originates in the sphenopalatine forame, causing epistaxes and nasal obstruction. Objective: To retrospectively describe our experience in the diagnosis and treatment of patients with juvenile nasopharyngeal angiofibroma. Scientific drawing: Retrospective, descriptive study conducted after approval from the Ethics Committee of the Federal University of Sergipe (protocol 0114.0.107.000 -11). Methods: We analyzed findings in 20 patients who underwent surgery between 2004 and 2011. Factors analyzed include patient age and gender, symptoms, stages, treatment, length of surgery, intraoperatory bleeding, postoperative need for nasal tampons, hospitalization time, complications, and tumor recurrence. Results: Patients were aged 10-29 years. All patients were treated surgically, including 17 who underwent endoscopic surgery. The mean operation time was 120 min, and the mean bleeding volume was 300 mL. Seventeen patients required clamping of the external carotids and tumor embolization. Conclusion: Endoscopic surgery alone or with other conventional techniques was safe for the treatment of angiofibromas of different stages...

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Introduction: Cochlear Implants are important for individuals with severe to profound bilateral sensorineural hearing loss. Objective: Evaluate the experience of cochlear implant center of Otorhinolaryngology through the analysis of records of 9 patients who underwent cochlear implant surgery. Methods: This is a retrospective study performed with the patients records. Number 0191.0.107.000-11 ethics committee approval. We evaluated gender, etiology, age at surgery, duration of deafness, classification of deafness, unilateral or bilateral surgery, intraoperative and postoperative neural response and impedance of the electrodes in intraoperative and preoperative tests and found those that counter-indicated surgery. Results: There were 6 pediatric and 3 adult patients. Four male and 5 female. Etiologies: maternal rubella, cytomegalovirus, ototoxicity, meningitis, and sudden deafness. The age at surgery and duration of deafness ranged from 2 - 46 years and 2 - 18 years, respectively. Seven patients were pre-lingual. All had profound bilateral PA. There were 7 bilateral implants. Intraoperative complications: hemorrhage. Complications after surgery: vertigo and internal device failure. In 7 patients the electrodes were implanted through. Telemetry showed satisfactory neural response and impedance. CT and MRI was performed in all patients. We found enlargement of the vestibular aqueduct in a patient and incudomalleolar malformation. Conclusion: The cochlear implant as a form of auditory rehabilitation is well established and spreading to different centers specialized in otoaudiology. Thus, the need for structured services and trained professionals in this type of procedure is clear...

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A esporotricose é uma micose subcutânea causada pelo fungo dimórfico Sporothrix schenckii. Este artigo descreve o primeiro caso de esporotricose óssea e cutânea, em canino, na cidade de Pelotas, Rio Grande do Sul. O animal apresentava lesões ulceradas e crostosas, há aproximadamente três anos no plano nasal e membro torácico direito, dispnéia e apatia. Para confirmação do diagnóstico, foram realizados exames micológico, histopatológico, radiológico e hematológico. O animal foi tratado durante três meses com 10mg/kg de itraconazol,por via oral, obtendo-se a cura das lesões. Este estudo alerta clínicos de pequenos animais para a ocorrência desta micose em caninos na região de Pelotas, RS.

The sporotrichosis is a subcutaneous mycosis caused by dimorphic fungus Sporothrix schenckii. This article describes the first cutaneous and osseous sporotrichosis case in canine in the Pelotas city, Rio Grande do Sul. The animal presented crusts and ulcerated lesions,approximately the three years in the nasal plan and right hind-foot,dispneic and apathy. Mycological, histopathological, radiological and hematological diagnosis was realized. The animal was treated by three months with itraconazole, administered orally at a dosage of 10mg/kg, until lesions disappeared. This study alert small animals clinicians for the occurrence of this mycosis in dogs in the region of Pelotas, RS.

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A esporotricose é uma micose subcutânea causada pelo fungo dimórfico Sporothrix schenckii. Este artigo descreve o primeiro caso de esporotricose óssea e cutânea, em canino, na cidade de Pelotas, Rio Grande do Sul. O animal apresentava lesões ulceradas e crostosas, há aproximadamente três anos no plano nasal e membro torácico direito, dispnéia e apatia. Para confirmação do diagnóstico, foram realizados exames micológico, histopatológico, radiológico e hematológico. O animal foi tratado durante três meses com 10mg/kg de itraconazol,por via oral, obtendo-se a cura das lesões. Este estudo alerta clínicos de pequenos animais para a ocorrência desta micose em caninos na região de Pelotas, RS.(AU)

The sporotrichosis is a subcutaneous mycosis caused by dimorphic fungus Sporothrix schenckii. This article describes the first cutaneous and osseous sporotrichosis case in canine in the Pelotas city, Rio Grande do Sul. The animal presented crusts and ulcerated lesions,approximately the three years in the nasal plan and right hind-foot,dispneic and apathy. Mycological, histopathological, radiological and hematological diagnosis was realized. The animal was treated by three months with itraconazole, administered orally at a dosage of 10mg/kg, until lesions disappeared. This study alert small animals clinicians for the occurrence of this mycosis in dogs in the region of Pelotas, RS.(AU)

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A esporotricose é uma micose, subcutânea e zoonótica, causada pelo fungo dimórfico Sporothrix schenckii que afeta animais e humanos. A micose em cães era considerada rara devido aos poucos relatos descritos na literatura, no entanto, nos últimos anos observou-se um crescente registro de casos desta doença no Brasil. Neste estudo foram analisadas as características clínicas da esporotricose em três cães diagnosticados no Laboratório de Micologia (FV-UFPel), os quais apresentavam dispnéia, secreção nasal e espirros. Dois destes demonstravam também, lesões cutâneas ulceradas e crostosas no plano nasal. Embora um dos animais não apresentasse lesões cutâneas, os sinais respiratórios eram evidentes assim como a presença de linfadenopatia. Este estudo alerta para a ocorrência da esporotricose em cães na região de Pelotas e Rio Grande, e salienta para a similaridade das lesões observadas, com outras doenças infecciosas e neoplásicas, o que torna importante a realização de diagnóstico diferencial.

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A esporotricose é uma micose, subcutânea e zoonótica, causada pelo fungo dimórfico Sporothrix schenckii que afeta animais e humanos. A micose em cães era considerada rara devido aos poucos relatos descritos na literatura, no entanto, nos últimos anos observou-se um crescente registro de casos desta doença no Brasil. Neste estudo foram analisadas as características clínicas da esporotricose em três cães diagnosticados no Laboratório de Micologia (FV-UFPel), os quais apresentavam dispnéia, secreção nasal e espirros. Dois destes demonstravam também, lesões cutâneas ulceradas e crostosas no plano nasal. Embora um dos animais não apresentasse lesões cutâneas, os sinais respiratórios eram evidentes assim como a presença de linfadenopatia. Este estudo alerta para a ocorrência da esporotricose em cães na região de Pelotas e Rio Grande, e salienta para a similaridade das lesões observadas, com outras doenças infecciosas e neoplásicas, o que torna importante a realização de diagnóstico diferencial.

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A esporotricose é uma micose, subcutânea e zoonótica, causada pelo fungo dimórfico Sporothrix schenckii que afeta animais e humanos. A micose em cães era considerada rara devido aos poucos relatos descritos na literatura, no entanto, nos últimos anos observou-se um crescente registro de casos desta doença no Brasil. Neste estudo foram analisadas as características clínicas da esporotricose em três cães diagnosticados no Laboratório de Micologia (FV-UFPel), os quais apresentavam dispnéia, secreção nasal e espirros. Dois destes demonstravam também, lesões cutâneas ulceradas e crostosas no plano nasal. Embora um dos animais não apresentasse lesões cutâneas, os sinais respiratórios eram evidentes assim como a presença de linfadenopatia. Este estudo alerta para a ocorrência da esporotricose em cães na região de Pelotas e Rio Grande, e salienta para a similaridade das lesões observadas, com outras doenças infecciosas e neoplásicas, o que torna importante a realização de diagnóstico diferencial.