RESUMO
AIM: The aim of this review was to evaluate the scientific literature regarding the cytogenetic damage in oral exfoliated cells of adult patients submitted to panoramic X-ray. MATERIALS AND METHODS: An extensive search of the literature was conducted on PubMed, Scopus and Web of Science databases for all studies published until April 2021 using combinations of the following keywords: "panoramic X-ray," "DNA damage," "genetic damage", "genotoxicity", "mutagenicity", cytotoxicity", "buccal cells", "oral mucosa", "tongue", "gingiva", "micronucleus assay", according to the PRISMA guidelines. All clinical studies in English language were included in the study. A total of 10 studies were identified. RESULTS: As expected, the results regarding the cytogenetic damage induced by panoramic X-ray are conflicting. Some authors have demonstrated that panoramic X-ray induces mutagenesis in oral cells, whereas others did not. After reviewing the 10 studies, two were classified as strong, four were considered moderate, and four were considered weak, according to the quality assessment components of the Effective Public Health Practice Project (EPHPP). Meta-analysis data revealed a negative response related to mutagenicity in oral cells by panoramic X-ray. CONCLUSION: Taken together, this review failed to demonstrate the association between micronucleus frequency and panoramic X-ray.
Assuntos
Análise Citogenética/métodos , Mucosa Bucal/química , Radiografia Panorâmica/efeitos adversos , Dano ao DNA , Humanos , Testes para Micronúcleos , Mucosa Bucal/efeitos dos fármacos , MutaçãoRESUMO
Este artigo relata o caso de uma paciente do sexo feminino, com 17 anos de idade, cujo segundo molar permanente inferior do lado direito apresentava-se incluso e impactado. Após a extração do terceiro molar do mesmo lado foi exposta a superfície disto-vestibular do segundo molar impactado, colado um acessório ortodôntico e sua desinclusão foi realizada com fio e mola de Nitinol. Após aproximadamente 5 meses o dente se encontrava posicionado no arco dentário