RESUMO
Ultrastructural features of the cheek oral mucosa of rats (Rattus norvegicus) submitted to experimental chronic alcoholism were studied by transmission electron microscopy. Sixty male rats aged three months and with a mean body weight of 250 g were divided into two experimental groups. The control group received a solid diet (Purina rat chow) and tap water ad libitum. The alcoholic group received the same solid diet but was only allowed to drink sugar cane liquor dissolved in 30 degrees Gay Lussac (v/v). The animals of the two groups were weighed and sacrificed after 60, 120, and 180 days of treatment. Samples of the oral mucosa from the cheek region were dissected and processed for ultrastructural analysis. The results showed cell alterations in the basal and intermediate layer of the mucosal epithelium. The most frequent alterations observed were an increased intercellular space, the presence of lipid droplets in the cytoplasm, and irregular nuclei with a pyknotic aspect.
Assuntos
Alcoolismo/patologia , Mucosa Bucal/efeitos dos fármacos , Mucosa Bucal/ultraestrutura , Animais , Núcleo Celular/efeitos dos fármacos , Núcleo Celular/ultraestrutura , Bochecha/patologia , Citoplasma/efeitos dos fármacos , Citoplasma/ultraestrutura , Desmossomos/efeitos dos fármacos , Desmossomos/ultraestrutura , Modelos Animais de Doenças , Lipídeos , Masculino , Microscopia Eletrônica , RatosRESUMO
Most investigators consider the caroticotympanic artery to be a normal branch of the petrous portion of the internal carotid artery, although some authors disagree. The present study was conducted on forty human temporal bones removed from adult cadavers of both sexes. Twenty pieces were injected and dissected under a surgical microscope, 10 pieces were injected and submitted to corrosion, and 10 were injected and diaphanized in order to observe the frequency of the caroticotympanic artery in the petrous portion of the internal carotid artery. The caroticotympanic artery was not observed in any of the pieces submitted to microdissection and was observed in only 1 of the pieces (10%) submitted to corrosion and also in 1 of the diaphanized pieces (10%). In both cases, only one artery was present. Based on the present results showing that the rate of occurrence of the caroticotympanic artery was very low by the three techniques utilized (microdissection 0%; corrosion 10%; diaphanization 10%), it is possible to conclude that, anatomically, the artery should be considered as a variation and not as a normal branch of the petrous portion of the internal carotid artery, in agreement with most literature reports.
Assuntos
Artéria Carótida Interna/anatomia & histologia , Orelha Média/anatomia & histologia , Orelha Média/irrigação sanguínea , Osso Petroso/anatomia & histologia , Osso Petroso/irrigação sanguínea , Artéria Carótida Interna/anormalidades , Feminino , Humanos , MasculinoRESUMO
In this paper was investigated relationship between anterior malleus ligament and nerve chorda tympani, according the sex and the ethnic group. It was used 48 temporal bones.