RESUMO
BACKGROUND: Most clinical cases of osteomyelitis in dogs involve infectious agents, especially bacteria and fungi. The characterization of these microorganisms may aid in the prevention and treatment of disease. OBJECTIVE: The aim of this study was to evaluate retrospectively microbiological cultures and in vitro antimicrobial susceptibility profile of isolates from 52 cases of bacterial osteomyelitis in long bones of dogs over 2000-2013. In 78% of the cases injuries were caused by a motor vehicle accident, but there were a few cases of dog bites (17%) and ascending infection due to pododermatitis (5%). ANIMALS AND METHODS: The isolated microorganisms were identified based on conventional phenotypic methods. In vitro disk diffusion test was performed using 30 different antimicrobials. RESULTS: The isolates were obtained from femur (28%), humerus (16%), tibia (31%), and radius/ulna (25%). Among 52 cases, culture was positive in 88% of cases. Thirteen genus of different species of microorganisms were isolated. The most common microorganisms isolated were Staphylococcus spp. and Escherichia coli followed by Streptococcus spp., enteric bacteria, Corynebacterium sp. and anaerobic bacteria. In 42% of cases cultures were mixed. The most effective drugs against isolated bacteria were amoxicillin and clavulanate potassium (79%) followed by ceftriaxone (69%). High-resistance rates were documented against azithromycin (80%), penicillin (59%), and clindamycin (59%). CONCLUSIONS: The present study highlights diverse etiologic agents in cases of infectious bacterial osteomyelitis, with predominance of Staphylococcus genus, and reinforces the importance of obtaining cultures and susceptibility profiles given the high rates of antimicrobial resistance.
Assuntos
Antibacterianos/farmacologia , Bactérias/efeitos dos fármacos , Doenças do Cão/microbiologia , Farmacorresistência Bacteriana , Osteomielite/veterinária , Animais , Brasil , Cães , Testes de Sensibilidade Microbiana/veterinária , Osteomielite/microbiologia , Estudos RetrospectivosRESUMO
O escore de Apgar é utilizado amplamente nas maternidades de todo o mundo como o melhor métodopara avaliação clínica do neonato no momento imediato após o parto. Na medicina veterinária, estudos vêmsendo realizados e adaptações ao método original são desenvolvidas para um auxílio eficaz na identificação dosneonatos de risco. A pontuação serve para identificar neonatos de alto risco que necessitem de atenção médica,principalmente nos primeiros minutos de vida, possibilitando, assim, uma intervenção mais rápida e eficiente.
The Apgar score is widely used in hospitals around the world as the best method for clinical evaluationof the newborn immediately after delivery. In veterinary medicine studies have been developed to provideeffective aid in the identification of risk newborns. The score is used to identify high-risk neonates requiringmedical attention, especially in the first minutes of life, promoting a faster and more efficient response.
Assuntos
Animais , Criança , Medicina Veterinária , Neonatologia , Índice de ApgarRESUMO
O escore de Apgar é utilizado amplamente nas maternidades de todo o mundo como o melhor métodopara avaliação clínica do neonato no momento imediato após o parto. Na medicina veterinária, estudos vêmsendo realizados e adaptações ao método original são desenvolvidas para um auxílio eficaz na identificação dosneonatos de risco. A pontuação serve para identificar neonatos de alto risco que necessitem de atenção médica,principalmente nos primeiros minutos de vida, possibilitando, assim, uma intervenção mais rápida e eficiente.(AU)
The Apgar score is widely used in hospitals around the world as the best method for clinical evaluationof the newborn immediately after delivery. In veterinary medicine studies have been developed to provideeffective aid in the identification of risk newborns. The score is used to identify high-risk neonates requiringmedical attention, especially in the first minutes of life, promoting a faster and more efficient response.(AU)