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1.
J Vet Pharmacol Ther ; 45(5): 473-480, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35762629

RESUMO

Several different tick species are known to infest horses. Aside from causing serious health and welfare issues, including anaemia, ill thrift, and immunosuppression, ticks can transmit a variety of important, sometimes zoonotic, pathogens. The successful prevention and treatment of tick infestations have been described, but the information is scarce and, in many instances, anecdotal. Here we describe a practical and affordable prevention of tick infestation by using abamectin-impregnated cattle ear tags affixed to a safety collar. We have assessed the radial distribution of abamectin by analyzing hair samples, as well as its efficacy against tick infestations. The study results show that abamectin distributes across horse skin from the site of application and its associated effectiveness in reducing the tick burden.


Assuntos
Doenças dos Bovinos , Doenças dos Cavalos , Infestações por Carrapato , Carrapatos , Animais , Bovinos , Orelha Externa , Doenças dos Cavalos/tratamento farmacológico , Doenças dos Cavalos/prevenção & controle , Cavalos , Ivermectina/análogos & derivados , Infestações por Carrapato/tratamento farmacológico , Infestações por Carrapato/prevenção & controle , Infestações por Carrapato/veterinária
3.
J Vet Pharmacol Ther ; 44(4): 568-574, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33078856

RESUMO

The recent changes in curricula in veterinary medicine have changed the delivery and focus on veterinary pharmacology and therapeutics, resulting in a perceived lack of knowledge of pharmacology and therapeutic decision making in recent graduates. To aid veterinary pharmacologists and clinicians teaching clinical pharmacology, core competencies were drafted by a working group. Following this process, a Delphi study was performed to come to a consensus on day-1 competencies in veterinary pharmacology and therapeutics. The described competencies could be useful to a variety of stakeholders in veterinary pharmacology, including those teaching veterinary pharmacology worldwide. Secondly, they could form the basis of vertical alignment of the subject within schools and across the world, as well as serving to frame the integration of veterinary pharmacology and therapeutics into competency-based veterinary education.


Assuntos
Farmacologia Clínica , Animais , Currículo , Técnica Delphi
4.
J Vet Pharmacol Ther ; 43(5): 421-428, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32488977

RESUMO

Ectoparasites infestations are a growing concern to horse owners and equine veterinarians alike. Ectoparasites cause significant health and welfare issues and can potentially can serve as vectors for a variety of pathogens. The prevalence of ectoparasites increases around the world, and especially in horses information on the successful prevention and treatment of ectoparasite infestations in scarce and in many instances anecdotal. This poses a challenge to the equine veterinarian and off-label use of drugs can lead to detrimental effects in horses. In this review we describe the current available evidence for the prevention and treatment of ectoparasite infestations in horses. Only a very limited number of products is approved for the use in horses and fortunately many of the other products that are used in an off-label manner appear to be safe in horses. Future research in this area should aim at providing PK/PD modelling data to assure appropriate and safe dose regimen to prevent and treat ectoparasite infestations in horses.


Assuntos
Ectoparasitoses/veterinária , Doenças dos Cavalos/parasitologia , Animais , Ectoparasitoses/tratamento farmacológico , Ectoparasitoses/prevenção & controle , Doenças dos Cavalos/tratamento farmacológico , Doenças dos Cavalos/prevenção & controle , Cavalos
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