RESUMO
The present study reports two cases of oral perineuriomas, including a clinicopathologic review of the 39 published cases (17 intraneural and 22 extraneural perineuriomas) in the English language literature. In the first case, the tumor occurred in an 84-year-old male as a painless, asymptomatic, 20-mm submucosal nodule on the right lower mucobuccal fold near to the premolar area. In the second case, a 46-year-old female presented with a painless, 25-mm, slow-growing, fibrous, pedunculated nodule on the right buccal mucosa. In the first case, the tumor was composed of spindle cells arranged in a storiform pattern, classified as intraneural perineurioma; and in the second, it was an extraneural perineurioma, showing a whorled myxoid stroma. Immunohistochemical analysis confirmed the diagnosis by showing positivity for vimentin, EMA, and Glut-1 in case 1 and EMA, Glut-1, Claudin-1, and CD34 (focally) in case 2. Complete surgical removal was performed for both tumors, and there was no evidence of local recurrence after a long-term follow-up.
Assuntos
Mucosa Bucal/patologia , Neoplasias Bucais/patologia , Neoplasias de Bainha Neural/patologia , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/cirurgia , Neoplasias de Bainha Neural/cirurgiaRESUMO
Denosumab-related osteonecrosis of the jaws (DRONJ) is a recently described entity that shares many common clinical and radiological features with bisphosphonate-related osteonecrosis of the jaws (BRONJ). The aim of the present study is to report a case of DRONJ affecting the anterior mandible of a 58-year-old male treated with denosumab to prevent skeletal-related events associated with prostate cancer. Conservative surgery in conjunction with antibiotic therapy and discontinuation of denosumab use were effective in managing the condition and the patient remains free of clinical and radiological changes after a 38 month follow-up.
Assuntos
Osteonecrose da Arcada Osseodentária Associada a Difosfonatos/cirurgia , Conservadores da Densidade Óssea/efeitos adversos , Denosumab/efeitos adversos , Antibacterianos/uso terapêutico , Osteonecrose da Arcada Osseodentária Associada a Difosfonatos/diagnóstico por imagem , Terapia Combinada , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The intraoral vertical osteotomy is a versatile and simple technique usually applied to correct mandibular prognathism. Its greatest advantages include ease of performance and minimum neurosensory disturbances, whereas maxillomandibular fixation is pointed as its major disadvantage. Another important concern about this technique is condylar displacement, which may lead to temporomandibular dysfunction. Technical notes to avoid condylar luxation are discussed after 15 years of experience using this osteotomy as the technique of choice to correct mandibular prognathism. Three similar cases are presented, where 1 condyle was displaced from the glenoid fossa, resulting in mandibular deviation during function in patients requiring small mandibular setback.
Assuntos
Mandíbula/cirurgia , Osteotomia/métodos , Prognatismo/cirurgia , Transtornos da Articulação Temporomandibular/prevenção & controle , Adulto , Feminino , Humanos , Técnicas de Fixação da Arcada Osseodentária , Registro da Relação Maxilomandibular , Côndilo Mandibular/patologia , Modalidades de Fisioterapia , Prognatismo/diagnóstico por imagem , Radiografia Panorâmica , Transtornos da Articulação Temporomandibular/etiologia , Dimensão VerticalRESUMO
BACKGROUND: Fine-needle aspiration biopsy (FNAB) is useful in diagnosis of major salivary gland adenoid cystic carcinoma (ACC), but it has been rarely reported on minor salivary gland ACC. OBJECTIVE: The aim of this study was to report the utility of FNAB on diagnosis of ACC involving minor salivary glands. STUDY DESIGN: Three patients presenting ACC involving the palate (2 cases) and buccal mucosa (1 case), with a mean age of 36 years and 2:1 female-to-male ratio, were included in the study. All of the patients were submitted to FNAB for diagnostic purposes. RESULTS: All smears were stained with hematoxylin-eosin, Papanicolaou, and Diff-Quik and showed the presence of small polyhedral cells with hyperchromatic nuclei and extracellular basophilic globular amorphous substance, compatible with ACC. Diagnosis of the 3 cases was subsequently confirmed through histopathology. CONCLUSION: The FNAB was easy to perform and cost-effective, and proved to be an useful adjunctive tool in diagnosis of intraoral ACC.
Assuntos
Biópsia por Agulha Fina/métodos , Carcinoma Adenoide Cístico/patologia , Neoplasias das Glândulas Salivares/patologia , Glândulas Salivares Menores/patologia , Adulto , Núcleo Celular/ultraestrutura , Bochecha/patologia , Corantes , Citodiagnóstico/métodos , Citoplasma/ultraestrutura , Diagnóstico Diferencial , Espaço Extracelular , Feminino , Corantes Fluorescentes , Humanos , Masculino , Pessoa de Meia-Idade , Mucosa Bucal/patologia , Neoplasias Palatinas/patologiaRESUMO
This case report describes the treatment of a 25-year-old woman with anterior open bite, Class II skeletal malocclusion, and a history of temporomandibular joint pain and sounds. She also had significant anteroposterior and vertical discrepancies and a convex profile with protrusive lips. Intraorally, she had an anterior open bite of 3 mm and an overjet of 5 mm. Mandibular surgical rotation, associated with mandibular incisor extraction, was performed to reduce the protrusion, close the open bite, and minimize the temporomandibular joint disorder.