RESUMO

Therapeutic plasma exchange (TPE) can improve disability recovery after neuromyelitis optica spectrum disease (NMOSD) attacks, but its effectiveness and safety in Latin-American patients with access barriers and diverse ethnicity is underexplored. We carried out a retrospective cohort study with NMOSD patients that underwent TPE. 84 NMOSD attacks in 68 patients were evaluated. Despite a median 25-day delay from symptom onset to TPE, 65,5% of patients showed significant improvement. Adverse events occurred in 39% of patients, usually transitory and with no fatalities.

Assuntos

Neuromielite Óptica , Humanos , Neuromielite Óptica/diagnóstico , Troca Plasmática , Estudos Retrospectivos , Brasil/epidemiologia , Etnicidade , Aquaporina 4