RESUMO

We report the case of a 42 year-old woman with myasthenia gravis associated with a malignant thymoma. Despite surgery, chemotherapy and radiotherapy, the thymoma showed soft tissues, pleural and mediastinic progression. Unexpectedly, a complete remission of the thymoma was confirmed by FDG-PET after four cycles of immunoglobulins, administered as treatment for a myasthenic crisis. To our knowledge this is the first case report of complete remission of a malignant thymoma with immunoglobulin therapy.

Assuntos

Imunoglobulinas Intravenosas/uso terapêutico , Fatores Imunológicos/uso terapêutico , Miastenia Gravis/complicações , Miastenia Gravis/tratamento farmacológico , Timoma/tratamento farmacológico , Timoma/etiologia , Neoplasias do Timo/tratamento farmacológico , Neoplasias do Timo/etiologia , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Feminino , Humanos , Indução de Remissão , Neoplasias Torácicas/tratamento farmacológico , Neoplasias Torácicas/secundário , Timoma/secundário , Neoplasias do Timo/patologia , Falha de Tratamento