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OBJECTIVE: To systematically review the literature regarding the concordance of sleep bruxism (SB) between monozygotic (MZ) and dizygotic (DZ) twins. METHODS: The registration for this systematic review was accomplished in the International Prospective Register of Systematic Reviews (PROSPERO, No. CRD42021251751). As of July 2022, four databases were searched, including PubMed, Scopus, Embase, and Web of Science, as well as the grey literature in Google Scholar and OpenGrey. Observational studies evaluating SB in MZ and DZ twins of any age and sex were included. For the evaluation of the risk of bias, the Joanna Briggs checklist was utilized. The certainty of evidence was assessed via the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. Pooled and subgroup meta-analyses were performed to estimate concordance of SB ââbetween twins (p < 0.05). RESULTS: In total, 3,155 records were identified. In the qualitative analysis, eleven studies were included; of these, seven were included in the meta-analysis. The majority of the articles exhibited a low risk of bias (63.6%). Greater SB concordance was observed between MZ twins than between DZ twins in the analysis of general concordance (OR = 1.47; 95% CI = 1.07-2.02) and also positive concordance (OR = 1.53; 95% CI = 1.29-1.81). Within the subgroup analyses, the significance of the findings remained only for the reported/self-reported SB regarding general concordance (OR = 1.44; 95% CI = 1.07-1.95) and positive concordance (OR = 1.55; 95% CI = 1.28-1.88). Low certainty of the evidence was observed for the general concordance analysis, while moderate certainty was observed for the positive concordance. CONCLUSION: There was a higher concordance of SB in MZ twins compared to DZ twins, indicating a possible genetic influence on the condition's occurrence.
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OBJECTIVE: To determine the association between genetic factors and molar-incisor hypomineralisation (MIH) and/or hypomineralised second primary molars by means of a systematic review. DESIGN: A search was performed in Medline-PubMed, Scopus, Embase and Web of Science databases; manual search and search in gray literature were also performed. Selection of articles was performed independently by two researchers. A third examiner was involved in cases of disagreement. Data extraction was performed using an Excel® spreadsheet and independent analysis was performed for each outcome. RESULTS: Sixteen studies were included. There was an association between MIH and genetic variants related to amelogenesis, immune response, xenobiotic detoxification and other genes. Moreover, interactions between amelogenesis and immune response genes, and SNPs in the aquaporin gene and vitamin D receptors were associated with MIH. Greater agreement of MIH was found in pairs of monozygotic twins than dizygotic twins. The heritability of MIH was 20 %. Hypomineralised second primary molars was associated with SNPs in the hypoxia-related HIF-1 gene and methylation in genes related to amelogenesis. CONCLUSION: With very low or low certainty of evidence, an association was observed between MIH and SNPs in genes associated with amelogenesis, immune response, xenobiotic detox and ion transport. Interactions between genes related to amelogenesis and immune response as well as aquaporin genes were associated to MIH. With very low certainty of evidence, hypomineralised second primary molars was associated to a hypoxia-related gene and to methylation in genes related to amelogenesis. Moreover, higher agreement of MIH in pairs of monozygotic twins than dizygotic twins was observed.
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Hipoplasia do Esmalte Dentário , Hipomineralização Molar , Humanos , Hipoplasia do Esmalte Dentário/genética , Xenobióticos , Amelogênese/genética , Dente Molar , PrevalênciaRESUMO
PURPOSE: To determine the prevalence of probable sleep bruxism (SB) in preschoolers and associated factors. METHODS: A cross-sectional, population-based study was carried out with 862 dyads of parents/preschoolers aged 5 from Teresina, Brazil. Data collection was performed through a questionnaire answered by parents/guardians about socioeconomic, demographic, and health condition data. Each child was examined for diagnosis of probable SB based on the presence of dental wear associated or not with the report of teeth grinding by parents/guardians. The analysis of independent variables was stratified into four levels of determinants: demographic characteristics of the child (distal), characteristics of the family, environmental factors (intermediate), and health conditions (proximal). Descriptive analysis and bivariate and multivariate Poisson's regression were performed using a hierarchical approach (p < 0.05). RESULTS: The prevalence of probable SB was 36%. In the final adjusted multivariate hierarchical model, a preschooler who was the only child (PR = 1.25; 95%CI = 1.02-1.51), with breathing problems (PR = 1.43; 95%CI = 1.19-1.73), and having parents/guardians with possible sleep bruxism (PR = 1.65; 95%CI = 1.32-2.07) had a higher prevalence of probable SB. CONCLUSION: The prevalence of probable SB in preschoolers was high and associated with the condition of being an only child, the presence of breathing problems, and having parents/guardians with possible sleep bruxism.
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Filho Único/estatística & dados numéricos , Pais , Transtornos Respiratórios/epidemiologia , Bruxismo do Sono/epidemiologia , Brasil/epidemiologia , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Masculino , Prevalência , Fatores de Risco , Bruxismo do Sono/genética , Inquéritos e QuestionáriosRESUMO
OBJECTIVES: This cross-sectional observational study determined the prevalence and factors associated with molar-incisive hypomineralization (MIH) in quilombola children and adolescents in north-eastern Brazil. METHODS: The sample consisted of 251 children and adolescents (8 to 14 years old) living in the rural quilombola community Lagoas in São Raimundo Nonato, Piauí (census population). Sociodemographic and health-related data were collected from pre-, peri- and post-natal health records and a clinical examination for MIH diagnosis was performed by four previously trained and calibrated examiners. Descriptive data analysis and Poisson regression were performed. The magnitude of the association was determined by adjusted prevalence ratio (PR) and confidence intervals (95% CI). RESULTS: The prevalence of MIH was 46.6%. The presence of MIH was associated with gestational diabetes (PR = 2.49, 95% CI 2.08-2.99; p <0.001) and acute foetal distress (PR = 1.39; 95% CI 1.04-1.86; p = 0.025). CONCLUSION: It was concluded that the prevalence of MIH in the quilombola community was high and associated with gestational diabetes and acute foetal distress.
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Cárie Dentária , Incisivo , Adolescente , Criança , Estudos Transversais , Humanos , Dente Molar , PrevalênciaRESUMO
The scope of this study was to evaluate the prevalence and severity of dental fluorosis among 11 to 14-year-old schoolchildren in Teresina, Piauí, Brazil, which is a tropical city with a fluoridated public drinking water supply. It involved a cross-sectional observational study on a sample of 571 students in public and private schools. Informed Consent forms were approved for the data collection and the exams were conducted at the schools. Data were recorded on a questionnaire answered by the parents, regarding the socioeconomic and demographic characteristics and oral hygiene habits of the sample. The dental exam was performed qualified dental sugeons. The Thylstrup-Fejerskov (TF) index was used. The prevalence of fluorosis was 77.9%, and only 12.5% of the affected children had TF ≥ grade 3 (with aesthetic damage). The premolars were the teeth most affected by fluorosis. Among the students with the highest severity of fluorosis, 98.6% belonged to the lowest social bracket (> B2), 91.5% were born and had always lived in Teresina, 94.4% consumed water from the fluoridated public supply, 76% used toothpaste for children and 64% of mothers reported that they swallowed toothpaste. The prevalence of fluorosis was high, though the severity was low in individuals exposed to fluoridation since birth.
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Fluoretação , Fluorose Dentária/epidemiologia , Clima Tropical , Abastecimento de Água , Adolescente , Brasil/epidemiologia , Criança , Estudos Transversais , Água Potável , Feminino , Fluoretos , Humanos , PrevalênciaRESUMO
PURPOSE: To determine the prevalence of molar-incisor hypomineralization (MIH) in children and possible factors associated with this disorder. METHODS: This was a cross-sectional observational study of 594 11- to 14-year-olds from Teresina, Piauí, Brazil. The diagnosis of MIH was made based on criteria set by the European Academy of Pediatric Dentistry. To investigate possible associated factors, mothers completed a questionnaire. A descriptive analysis of the data, chi-square, Mann-Whitney, and Fisher tests and Poisson regression (PR) were performed. RESULTS: The prevalence of MIH was 18.4 percent (95 percent confidence interval [CI] equals 15.20 to 21.50). The maxillary molars were the teeth most affected by MIH (36.1 percent). MIH patients showed a higher number of mean DMF-T (PR equals 2.18; 95 percent CI equals 1.46 to 2.85) than those not affected by the condition. There was an association between MIH and preterm birth (PR equals 1.76; 95 percent CI equals 1.22 to 2.12) and between MIH and respiratory distress at birth (PR equals 1.83; 95 percent CI equals 1.25 to 2.18). CONCLUSIONS: The prevalence of MIH in schoolchildren was 18.4 percent. Those with MIH had a greater mean DMF-T than those without MIH. Preterm birth and respiratory distress were associated with MIH.
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Incisivo , Dente Molar , Adolescente , Brasil , Criança , Estudos Transversais , Hipoplasia do Esmalte Dentário/epidemiologia , HumanosRESUMO
PURPOSE: This study's purpose was to investigate the prevalence of dental fluorosis in children, whose parents had participated in an oral health program when the children were between zero and three years old, residing in a city with fluoridated water. METHODS: Group 1 consisted of 128 eight- to 12-year-olds whose parents had visited a program on at least five occasions when the children were zero to three years old and received education about tooth-brushing and the proper use of fluoridated toothpaste in this young age group. The prevalence of dental fluorosis in the permanent maxillary incisors, using the Thylstrup-Fejerskov index, in Group 1 was compared to that of an age-matched group of children (n=128) whose parents had not participated in the program (Group 2). RESULTS: Group 1 mothers reported higher education levels (P<.05). Group 1 children had a significantly lower prevalence (â¼42 percent) and severity (P<.05) of dental fluorosis than those in the control group (â¼61 percent). CONCLUSION: Children whose parents participated in a dental program that included counselling on the proper amount of fluoridated toothpaste when their children were between zero and three years old presented less frequently with dental fluorosis than a control group when examined at eight to 12 years old.
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Fluorose Dentária/prevenção & controle , Educação em Saúde Bucal , Fatores Etários , Cariostáticos/administração & dosagem , Cariostáticos/uso terapêutico , Estudos de Casos e Controles , Criança , Aconselhamento , Estudos Transversais , Escolaridade , Feminino , Fluoretação , Fluoretos/administração & dosagem , Fluoretos/uso terapêutico , Fluorose Dentária/classificação , Promoção da Saúde , Humanos , Incisivo/patologia , Renda , Masculino , Maxila , Mães/educação , Saúde Bucal , Escovação Dentária/métodos , Cremes Dentais/administração & dosagem , Cremes Dentais/uso terapêuticoRESUMO
This article reports the treatment and follow-up of a 10-year-old boy who had a politraumatic accident that resulted in severe displacement and fracture of the maxillary right central incisor. After clinical and radiographic examination, the tooth fragment was bonded with adhesive and the tooth crown underwent nonrigid splinting. Follow-up appointments were scheduled once a week during the first month, once during the second month, and every three months thereafter. Each follow-up appointment included a clinical examination, followed by radiographic and pulp sensitivity tests. After the fifth year, pulp necrosis was diagnosed following a sensitivity test and a periapical radiograph. Endodontic treatment was performed; the chemical-mechanical preparation and root canal fillings used calcium hydroxide paste manipulated with saline solution. The abovementioned paste was replaced twice during the first month; after that, propylenoglycol was used as the vehicle for manipulating the calcium hydroxide. The filling paste was replaced whenever the radiographic image showed resorption of the paste. The root canals were filled definitively seven years postaccident. Nine years postaccident, clinical and radiographic examination revealed a normal aspect.
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Colagem Dentária , Necrose da Polpa Dentária/terapia , Restauração Dentária Permanente/métodos , Tratamento do Canal Radicular , Fraturas dos Dentes/terapia , Criança , Necrose da Polpa Dentária/etiologia , Humanos , Incisivo/lesões , Masculino , Contenções Periodontais , Coroa do Dente/lesões , Fraturas dos Dentes/complicaçõesRESUMO
This article presents a case report (including the 10-year follow-up) of a 10-year-old patient who suffered displacement of the maxillary right central incisor, intrusion of the maxillary left central incisor, and crown fractures to the mesial angles of these teeth as a result of dental trauma. Treatment involved an interdisciplinary approach that utilized a pediatric dentist, an endodontist, and an orthodontist.