RESUMO

In Part II we discuss the following bacterial pathogens: Shigella, Salmonella (non-typhoidal), diarrheogenic E. coli (enterotoxigenic and enterohemorragic) and Campylobacter jejuni. In contrast to the enteric viruses and Vibrio cholerae discussed in Part I of this series, for the bacterial pathogens described here there is only one licensed vaccine, developed primarily for Vibrio cholerae and which provides moderate protection against enterotoxigenic E. coli (ETEC) (Dukoral(®)), as well as a few additional candidates in advanced stages of development for ETEC and one candidate for Shigella spp. Numerous vaccine candidates in earlier stages of development are discussed.

Assuntos

Vacinas Bacterianas/imunologia , Campylobacter jejuni/imunologia , Diarreia/prevenção & controle , Escherichia coli/imunologia , Gastroenterite/prevenção & controle , Salmonella/imunologia , Shigella/imunologia , Ensaios Clínicos como Assunto , Diarreia/epidemiologia , Diarreia/microbiologia , Diarreia/virologia , Aprovação de Drogas , Descoberta de Drogas , Avaliação Pré-Clínica de Medicamentos , Gastroenterite/epidemiologia , Gastroenterite/microbiologia , Gastroenterite/parasitologia , Gastroenterite/virologia , Humanos