RESUMO

The blaPER-2-harboring plasmid pCf587 (191,541 bp) belongs to lineage IncA/C1 and is closely related to pRA1. It contains a large resistance island including the blaPER-2 gene between two copies of ISKox2-like elements, the toxin-antitoxin module pemK-pemI, several other resistance genes inserted within a Tn2 transposon, a Tn21-like structure, and a class 1 integron. pCf587 belongs to sequence type 13 (ST13), a new plasmid multilocus sequence typing (pMLST) ST.

Assuntos

Citrobacter freundii/enzimologia , Plasmídeos/genética , Antibacterianos/farmacologia , Citrobacter freundii/efeitos dos fármacos , Citrobacter freundii/genética , Farmacorresistência Bacteriana Múltipla/genética , Integrons/genética , Testes de Sensibilidade Microbiana , Tipagem de Sequências Multilocus , Análise de Sequência de DNA , beta-Lactamases/genética , beta-Lactamases/metabolismo