RESUMO

AIM: Our aim was to identify independent determinants of rapid weight gain in infants at 3-4, 6, and 12 months of age. METHODS: A cohort study was conducted on Mexican term infants in public and private settings between March 2021 and May 2023. Rapid weight gain was defined as a ≥0.67 SD change in weight-for-age-Z-score from birth to 3-4, 6, and 12 months of age. Maternal and infant characteristics were described, and infant feeding practices, appetitive traits, weight, and length were analysed at 3-4, 6, and 12 months of age. Rapid weight gain predictors were determined using generalised linear regression models. RESULTS: In total, 168 infants were recruited (55% boys). Small-for-gestational-age status increased rapid weight gain risk 1.5 times, whereas large-for-gestational-age status represented a 20%-30% decrease. Slowness in eating decreased the risk by 10%. Protective factors were older maternal age and higher educational level, whereas formula feeding, early complementary feeding, greater food enjoyment, and satiety responsiveness increased the risk. CONCLUSIONS: Small for gestational age, slowness in eating, and feeding practices can be rapid weight gain predictors across the first year of life.

RESUMO

We aimed to analyze whether rapid weight gain (RWG) between the official weigh-in and the time of the fight was associated with fight success in MMA. A total of 700 professional MMA fights involving 1,400 weigh-ins from 21 MMA promotions regulated by the California State Athletic Commission were analyzed. Multilevel logistic regression accounting for individual (i.e. athlete) and cluster levels (i.e. fights) was used to analyze the association of all measures with a theoretical relationship with the dependent variable and without interdependency with one another (i.e. %RWG, sex, body mass division, competition level) with the fight outcome (i.e. win or loss). The odds ratios (OR) with 95% confidence intervals (95%CI) were calculated. The highest mean %RWG was found for the flyweight, bantamweight, featherweight, and lightweight divisions. The %RWG significantly predicted the fight outcome (ß = 0.044; OR = 1.045; 95%CI = 1.014-1.078; p = 0.005) so that for each 1% of additional RWG, the chance of winning increased by 4.5%. With the largest sample to date and in a "real-world" scenario, the present results suggest that the magnitude of RWG is linked to the chance of winning in MMA combats. It is suggested that regulatory commissions, confederations, and event organisers should consider regulating RWG, considering that, despite its detrimental impact on the athletes' health and performance, the potential advantage might stimulate athletes to invest in rapid weight loss, followed by gain after the official weigh-in to increase their chance of winning.

Assuntos

Artes Marciais , Aumento de Peso , Humanos , Atletas

RESUMO

OBJECTIVE: To identify systolic blood pressure (SBP) percentile trajectories in children and to describe the early-life risk factors and cardiometabolic correlates of those trajectories. STUDY DESIGN: Using age-, sex-, and height-specific SBP percentiles based on the American Academy of Pediatrics reference, we examined SBP trajectories using latent class mixed models from ages 3 to 8 years (n = 844) from the Growing Up in Singapore Towards healthy Outcomes-study, a Singaporean mother-offspring cohort study. We analyzed associations between SBP trajectories and early-life risk factors using multinomial logistic regression and differences across trajectories in cardiometabolic outcomes using multiple linear regression. RESULTS: Children were classified into 1 of 4 SBP percentile trajectories: "low increasing" (15%), "high stable" (47%), "high decreasing" (20%), and "low stable" (18%). Maternal hypertension during early pregnancy was a predictor of the "high stable" and "low increasing" SBP trajectories. Rapid child weight gain in the first 2 years of life was only associated with the "high stable" trajectory. Compared with children in the "low stable" trajectory, children in the "high stable" SBP trajectory had greater body mass index z scores, sum of skinfold thicknesses, waist circumference from ages 3 to 8 years, and abdominal adipose tissue (milliliters) at 4.5 years (adjusted mean difference [95% CI]: superficial and deep subcutaneous abdominal adipose tissue: 115.2 [48.1-182.3] and 85.5 [35.2-135.8]). Their fat mass (kilograms) (1.3 [0.6-2.0]), triglyceride levels (mmol/L) (0.10 [0.02-0.18]), and homeostasis model assessment of insulin resistance (0.28 [0.11 0.46]) at age 6 years were also greater but not their arterial thickness and stiffness. CONCLUSIONS: Reducing maternal blood pressure during pregnancy and infant weight gain in the first 2 years of life might help to prevent the development of high SBP.

Assuntos

Pressão Sanguínea/fisiologia , Doenças Cardiovasculares/epidemiologia , Fatores Etários , Glicemia/metabolismo , Índice de Massa Corporal , Doenças Cardiovasculares/diagnóstico , Criança , Pré-Escolar , Colesterol/sangue , Feminino , Humanos , Lactente , Modelos Logísticos , Masculino , Fatores de Risco , Singapura , Circunferência da Cintura

RESUMO

OBJECTIVE: To determine whether the same relationships between early-life risk factors and socioeconomic status (SES) with childhood body mass index (BMI) are observed in a modern cohort (2000) compared with a historic cohort (1947). STUDY DESIGN: The relationships between early-life factors and SES with childhood BMI were examined in 2 prospective birth cohorts from the same region, born 50 years apart: 711 children in the 1947 Newcastle Thousand Families Study (NTFS) and 475 from the 2000 Gateshead Millennium Study (GMS). The associations between birth weight, breastfeeding, rapid infancy growth (0-12 months), early-life adversity (0-12 months), and parental SES (birth and childhood) with childhood BMI z-scores and whether overweight/obese (BMI >91st percentile using UK 1990 reference) aged 9 years were examined using linear regression, path analyses, and logistic regression. RESULTS: In the NTFS, the most advantaged children were taller than the least (+0.91 height z-score, P = .001), whereas in GMS they had lower odds of overweight/obese than the least (0.35 [95% CI 0.14-0.86]). Rapid infancy growth was associated with increased BMI z-scores in both cohorts, and with increased likelihood of overweight/obese in GMS. CONCLUSIONS: This study suggests that children exposed to socioeconomic disadvantage or who have rapid infancy growth in modern environments are now at lower risk of growth restriction but greater risk of overweight.

Assuntos

Índice de Massa Corporal , Previsões , Obesidade Infantil/epidemiologia , Determinantes Sociais da Saúde , Adulto , Peso ao Nascer , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Morbidade/tendências , Obesidade Infantil/diagnóstico , Estudos Prospectivos , Fatores de Risco , Classe Social , Reino Unido/epidemiologia

RESUMO

BACKGROUND: Rapid postnatal weight gain is associated with risk of overweight and obesity, but it's unclear whether this holds in populations exposed to concurrent obesogenic risk factors and for children who have been extensively breastfed. This study investigates whether an increase in weight for age from birth to 1 year (infancy) and from 1 to 5 years (early childhood) predicts overweight and obesity, and waist circumference at 8 years, using data from a longitudinal cohort study in Peru. METHODS: Generalized estimating equations (GEE) models were constructed for overweight and obesity, obesity alone and waist circumference at 8 years versus rapid weight gain in infancy, and early childhood including adjusted models to account for confounders. RESULTS: Rapid weight gain in both periods was associated with double the risk of overweight and obesity, obesity alone at 8 years and increased waist circumference even after controlling for maternal BMI and education level, sex of child, height-for-age at 8 years, consumption of "fast food" and number of days of active exercise. The association was significant, with some differences, for children in both rural and urban environments. CONCLUSIONS: Rapid weight gain in infancy and in early childhood in Peru is associated with overweight and obesity at age 8 years even when considering other determinants of childhood obesity.