RESUMO

A coexistence of different renal tumors has rarely been reported. The most commonly described association is of Wilms tumor and renal cell carcinoma. Metanephric adenofibroma has also been associated with Wilms tumor or papillary renal cell carcinoma. Another reported association is metanephric adenoma and papillary renal cell carcinoma with sarcomatoid dedifferentiation. Herein we describe a complex renal tumor containing areas of metanephric adenofibroma, Wilms tumor, and undifferentiated renal cell carcinoma in a previously healthy 18-year-old boy. The tumor showed histologic and immunohistochemical features of these 3 different tumors, offering additional support to the view that these 3 tumors are related.

Assuntos

Adenofibroma/diagnóstico , Carcinoma de Células Renais/diagnóstico , Neoplasias Renais/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Tumor de Wilms/diagnóstico , Adenofibroma/metabolismo , Adenofibroma/terapia , Adolescente , Biomarcadores Tumorais/metabolismo , Carcinoma de Células Renais/metabolismo , Carcinoma de Células Renais/secundário , Carcinoma de Células Renais/terapia , Terapia Combinada , Evolução Fatal , Humanos , Neoplasias Renais/metabolismo , Neoplasias Renais/terapia , Masculino , Recidiva Local de Neoplasia , Neoplasias Primárias Múltiplas/metabolismo , Neoplasias Primárias Múltiplas/secundário , Neoplasias Primárias Múltiplas/terapia , Nefrectomia , Tumor de Wilms/metabolismo , Tumor de Wilms/secundário , Tumor de Wilms/terapia