RESUMO
La hiperplasia pseudoangiomatosa estromal de la mama es una patología benigna de rara aparición en mujeres, que hoy en día sigue generando incertidumbre en cuanto a su manifestación y al tratamiento definitivo. Nuestro objetivo será detallar el manejo y los resultados obtenidos luego de tratar a una paciente con esta patología atendida en hospital público durante la pandemia, que presentó gigantomastia bilateral a expensas de crecimiento y simetrización de mama contralateral afectada por HEP durante su estado gravídico.
Pseudoangimatous stromal hyperplasia of the breast, is a pathology of rare appearance, in women, which today continues to generate uncertainty regarding its manifestation and definitive treatment. Our objective will be to detail the management and results obtained after treating a patient with this pathology in a public hospital during a pandemic. who presented bilateral gigantomastia at the expense of growth and symmetrization of the contralateral breast affected by HEP during her pregnancy.
Assuntos
Humanos , Feminino , Gravidez , Adulto , Doenças Mamárias/terapia , Gravidez , Mastectomia Segmentar , Natimorto , Morte Fetal , Hiperplasia/patologia , Angiomatose/patologiaAssuntos
Coartação Aórtica/complicações , Anormalidades do Olho/complicações , Perda Auditiva Condutiva/etiologia , Síndromes Neurocutâneas/complicações , Angiomatose/patologia , Coartação Aórtica/diagnóstico , Coartação Aórtica/patologia , Pré-Escolar , Anormalidades do Olho/diagnóstico , Anormalidades do Olho/patologia , Feminino , Perda Auditiva Condutiva/diagnóstico , Hemangioma/patologia , Humanos , Síndromes Neurocutâneas/diagnóstico , Síndromes Neurocutâneas/patologia , Otoscopia , SíndromeAssuntos
Humanos , Feminino , Pré-Escolar , Criança , Coartação Aórtica/complicações , Anormalidades do Olho/complicações , Síndromes Neurocutâneas/complicações , Perda Auditiva Condutiva/etiologia , Coartação Aórtica/diagnóstico , Coartação Aórtica/patologia , Síndrome , Anormalidades do Olho/diagnóstico , Anormalidades do Olho/patologia , Síndromes Neurocutâneas/diagnóstico , Síndromes Neurocutâneas/patologia , Otoscopia , Perda Auditiva Condutiva/diagnóstico , Hemangioma/patologia , Angiomatose/patologiaRESUMO
OBJECTIVE: Primary cardiac tumors are rare lesions with different histological type. We reviewed our 17 years of experience in the surgical treatment and clinical results of primary non-myxoma cardiac tumors. METHODS: Between July 2000 and February 2017, 21 patients with primary cardiac tumor were surgically treated in our institution. The tumors were categorized as benign non-myxomas and malignants. Data including the demographic characteristics, details of the tumor histology and grading, cardiac medical and surgical history, surgical procedure of the patients were obtained from the hospital database. RESULTS: Eleven patients were diagnosed with benign non-myxoma tumor (male/female:7/4), ranging in age from 10 days to 74 years (mean age 30.9±26.5 years). Papillary ï¬broelastoma was the most frequent type (63.6%). There were two early deaths in benign group (all were rhabdomyoma), and mortality rate was 18%. The mean follow-up period was 69.3±58.7 months (range, 3 to 178 months). All survivals in benign group were free of tumor-related symptoms and tumor relapses. Ten patients were diagnosed with malignant tumor (sarcoma/lymphoma:8/2, male/female:3/7), ranging in age from 14 years to 73 years (mean age 44.7±18.9 years). Total resection could be done in only three (30%) patients. The mean follow-up period was 18.7±24.8 months (range, 0-78 months). Six patients died in the first 10 months. CONCLUSION: Complete resection of the cardiac tumors, whenever possible, is the main goal of surgery. Surgical resection of benign cardiac tumors is safe, usually curative and provides excellent long-term prognosis. On the contrary, malignant cardiac tumors still remain highly lethal.
Assuntos
Neoplasias Cardíacas/patologia , Neoplasias Cardíacas/cirurgia , Adulto , Idoso , Angiomatose/mortalidade , Angiomatose/patologia , Angiomatose/cirurgia , Criança , Pré-Escolar , Feminino , Fibroma/mortalidade , Fibroma/patologia , Fibroma/cirurgia , Neoplasias Cardíacas/mortalidade , Humanos , Recém-Nascido , Estimativa de Kaplan-Meier , Linfoma/mortalidade , Linfoma/patologia , Linfoma/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Rabdomioma/mortalidade , Rabdomioma/patologia , Rabdomioma/cirurgia , Sarcoma/mortalidade , Sarcoma/patologia , Sarcoma/cirurgia , Fatores de Tempo , Resultado do Tratamento , Carga TumoralRESUMO
Abstract Objective: Primary cardiac tumors are rare lesions with different histological type. We reviewed our 17 years of experience in the surgical treatment and clinical results of primary non-myxoma cardiac tumors. Methods: Between July 2000 and February 2017, 21 patients with primary cardiac tumor were surgically treated in our institution. The tumors were categorized as benign non-myxomas and malignants. Data including the demographic characteristics, details of the tumor histology and grading, cardiac medical and surgical history, surgical procedure of the patients were obtained from the hospital database. Results: Eleven patients were diagnosed with benign non-myxoma tumor (male/female:7/4), ranging in age from 10 days to 74 years (mean age 30.9±26.5 years). Papillary fibroelastoma was the most frequent type (63.6%). There were two early deaths in benign group (all were rhabdomyoma), and mortality rate was 18%. The mean follow-up period was 69.3±58.7 months (range, 3 to 178 months). All survivals in benign group were free of tumor-related symptoms and tumor relapses. Ten patients were diagnosed with malignant tumor (sarcoma/lymphoma:8/2, male/female:3/7), ranging in age from 14 years to 73 years (mean age 44.7±18.9 years). Total resection could be done in only three (30%) patients. The mean follow-up period was 18.7±24.8 months (range, 0-78 months). Six patients died in the first 10 months. Conclusion: Complete resection of the cardiac tumors, whenever possible, is the main goal of surgery. Surgical resection of benign cardiac tumors is safe, usually curative and provides excellent long-term prognosis. On the contrary, malignant cardiac tumors still remain highly lethal.
Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Pré-Escolar , Criança , Adulto , Pessoa de Meia-Idade , Idoso , Neoplasias Cardíacas/cirurgia , Neoplasias Cardíacas/patologia , Rabdomioma/cirurgia , Rabdomioma/mortalidade , Rabdomioma/patologia , Sarcoma/cirurgia , Sarcoma/mortalidade , Sarcoma/patologia , Fatores de Tempo , Estudos Retrospectivos , Resultado do Tratamento , Carga Tumoral , Estimativa de Kaplan-Meier , Fibroma/cirurgia , Fibroma/mortalidade , Fibroma/patologia , Neoplasias Cardíacas/mortalidade , Angiomatose/cirurgia , Angiomatose/mortalidade , Angiomatose/patologia , Linfoma/cirurgia , Linfoma/mortalidade , Linfoma/patologiaAssuntos
Angiomatose/patologia , Doenças Mamárias/patologia , Dermatopatias/patologia , Úlcera Cutânea/patologia , Adulto , Angiomatose/fisiopatologia , Biópsia por Agulha , Doenças Mamárias/fisiopatologia , Fármacos Dermatológicos/uso terapêutico , Diagnóstico Diferencial , Feminino , Humanos , Imuno-Histoquímica , Prognóstico , Recidiva , Higiene da Pele/métodos , Dermatopatias/fisiopatologia , Úlcera Cutânea/fisiopatologia , Cicatrização/fisiologiaAssuntos
Angiomatose/patologia , Doenças Mamárias/patologia , Dermatopatias/patologia , Úlcera Cutânea/patologia , Adulto , Angiomatose/fisiopatologia , Angiomatose/terapia , Biópsia por Agulha , Doenças Mamárias/fisiopatologia , Fármacos Dermatológicos/uso terapêutico , Diagnóstico Diferencial , Feminino , Humanos , Imuno-Histoquímica , Prognóstico , Recidiva , Higiene da Pele/métodos , Dermatopatias/fisiopatologia , Dermatopatias/terapia , Úlcera Cutânea/fisiopatologia , Cicatrização/fisiologiaRESUMO
OBJECTIVES: Breast hamartoma is an uncommon breast tumor that accounts for approximately 4.8% of all benign breast masses. The pathogenesis is still poorly understood and breast hamartoma is not a well-known disorder, so its diagnosis is underestimated by clinicians and pathologists. This study was designed to present our experience with breast hamartoma, along with a literature review. METHOD: We reviewed the demographic data, pathologic analyses and imaging and results of patients diagnosed with breast hamartoma between December 2003 and September 2013. RESULTS: In total, 27 cases of breast hamartoma operated in the Ankara University Medicine Faculty's Department of General Surgery were included in the study. All patients were female and the mean age was 41.8±10.8 years. The mean tumor size was 3.9±2.7 cm. Breast ultrasound was performed on all patients before surgery. The most common additional lesion was epithelial hyperplasia (22.2%). Furthermore, lobular carcinoma in situ was identified in one case and invasive ductal carcinoma was observed in another case. Immunohistochemical staining revealed myoid hamartoma in one case (3.7%). CONCLUSION: Breast hamartomas are rare benign lesions that may be underdiagnosed because of the categorization of hamartomas as fibroadenomas by pathologists. Pathologic examinations can show variability from one case to another. Thus, the true incidence may be higher than the literature indicates.
Assuntos
Angiomatose/patologia , Doenças Mamárias/patologia , Hamartoma/patologia , Hiperplasia/patologia , Adulto , Angiomatose/diagnóstico por imagem , Doenças Mamárias/diagnóstico por imagem , Feminino , Hamartoma/diagnóstico por imagem , Humanos , Hiperplasia/diagnóstico por imagem , Mamografia , Pessoa de Meia-Idade , Turquia , Ultrassonografia , Adulto JovemRESUMO
OBJECTIVES: Breast hamartoma is an uncommon breast tumor that accounts for approximately 4.8% of all benign breast masses. The pathogenesis is still poorly understood and breast hamartoma is not a well-known disorder, so its diagnosis is underestimated by clinicians and pathologists. This study was designed to present our experience with breast hamartoma, along with a literature review. METHOD: We reviewed the demographic data, pathologic analyses and imaging and results of patients diagnosed with breast hamartoma between December 2003 and September 2013. RESULTS: In total, 27 cases of breast hamartoma operated in the Ankara University Medicine Faculty's Department of General Surgery were included in the study. All patients were female and the mean age was 41.8±10.8 years. The mean tumor size was 3.9±2.7 cm. Breast ultrasound was performed on all patients before surgery. The most common additional lesion was epithelial hyperplasia (22.2%). Furthermore, lobular carcinoma in situ was identified in one case and invasive ductal carcinoma was observed in another case. Immunohistochemical staining revealed myoid hamartoma in one case (3.7%). CONCLUSION: Breast hamartomas are rare benign lesions that may be underdiagnosed because of the categorization of hamartomas as fibroadenomas by pathologists. Pathologic examinations can show variability from one case to another. Thus, the true incidence may be higher than the literature indicates. .