RESUMO
Introducción: no son pocos los esfuerzos que se realizan para combatir el cáncer cérvicouterino, a pesar de que existe un programa de detecci¾n precoz, estamos lejos aún de alcanzar la meta propuesta. Objetivo: conocer el comportamiento del cáncer cérvicouterino en el municipio de San Antonio del Sur de la provincia Guantánamo en el periodo 2006-2010. Métodos: el universo de estudio quedó constituido por las 254 pacientes que tuvieron una citología orgánica con diagnóstico positivo de lesiones premalignas o malignas de cuello uterino. Los datos se extrajeron de las tarjetas de citología de cada área de salud, se procesaron en hojas de cálculo de Microsoft Excel, se expresaron en números absolutos y porcientos y se representaron en tablas y gráficos...
Introduction: many efforts are made to fight against the cervicouterine cancer despite a program of early detection the goal is far from to be achieved yet. Objective: to know the behavior of cervicouterine cancer in the San Antonio del Sur municipality in the Guantánamo province during 2006-2010. Methods: the study universe included 254 patients with a organic cytology and positive diagnosis of premalignant or malignant lesions of cervix. Data were collected from the cytology cards of each health area, the calculus sheets of Microsoft Excel were processed, expressed in absolute figures and percentages represented in tables and charts...
Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Lesões Pré-Cancerosas/patologia , Displasia do Colo do Útero/secundário , Neoplasias do Colo do Útero/patologia , Técnicas Citológicas , Epidemiologia Descritiva , Estudos RetrospectivosRESUMO
OBJECTIVE: The aim of the study was to evaluate blood leukocyte counts in patients with uterine cervical neoplasia. METHODS: Patients treated at a university hospital were reviewed retrospectively. Disease progression was monitored, beginning in 1990 to 2002, for at least 5 years. Blood count parameters included absolute leukocyte, neutrophil and lymphocyte counts, leukocytosis (white blood cells > 10³/µL), neutrophilia (neutrophils ≥ 70% of leukocytes), lymphopenia (lymphocytes ≤ 15% of leukocytes), and the neutrophil-lymphocyte ratio (NLR), categorized as less than 5 or 5 or greater. RESULTS: A total of 315 patients were enrolled: 182 (57.8%) with preinvasive neoplasia (cervical intraepithelial neoplasia [CIN] group), 95 (30.1%) with stages I to II (early group), and 38 patients (12.1%) with stages III to IV neoplasia (advanced group). Neutrophil and lymphocyte counts were elevated and reduced, respectively, at advanced stages compared with the CIN group (P < 0.05). Leukocytosis, neutrophilia, lymphopenia, and an NLR of 5 or greater were more frequent at advanced stages compared with the CIN and early-stage groups (P < 0.05). Moreover, neutrophilia was also significantly more frequent at early stage compared with the CIN group. The advanced group with neutrophilia had increased frequency of recidivism and metastasis than patients in the CIN group with neutrophilia (P < 0.05). CONCLUSIONS: Patients with advanced cervical cancer had significantly higher frequency of leukocyte alterations, although they may occur apart from the preinvasive stages. Overall, neutrophilia was the best indicator of cancer invasiveness.