RESUMO
Telogen effluvium (TE), a common hair disease, is supposed to be related to stress, which could be secondary to poor sleep. We call attention to the current COVID-19 pandemic, that is leading to an increase in the prevalence of sleep disturbances, and as a consequence, higher states of stress and anxiety, which are possible triggers for TE. In parallel, trichodynia is a sensorial symptom that is commonly related with hair diseases, including TE. We argue that substance P, a neuropeptide that has participation in the neuroinflammation and in the sleep regulation, may play a possible role in this scalp paresthesia. We suggest that there may be an association between this substrate and sleep, which can aggravate trichodynia and TE. Further studies on this subject could provide more evidence on these relationships, and help to improve the patients' quality of life and management of the condition.
Assuntos
COVID-19/psicologia , Doenças do Cabelo/etiologia , Transtornos do Sono-Vigília/metabolismo , Substância P/metabolismo , Animais , Ansiedade/etiologia , Ansiedade/psicologia , COVID-19/epidemiologia , Humanos , Camundongos , SARS-CoV-2 , Sono , Transtornos do Sono-Vigília/etiologia , Transtornos do Sono-Vigília/psicologia , Estresse Psicológico/etiologia , Estresse Psicológico/psicologiaRESUMO
OBJECTIVE: To determine the prevalence of skin changes during pregnancy and to relate their occurrence to specific factors in a population of south Brazil. METHODS: A cross-sectional analytical study was carried out with 1284 puerperal patients. A questionnaire about skin changes during pregnancy was developed and applied by the authors to all puerperal women admitted in a tertiary hospital in south Brazil. RESULTS: The appearance of striae during pregnancy was reported by 633 women (49.5%) and had a statistically significant association with primiparity, presence of stretch marks before pregnancy, and gestational weight gain above 21 kg. Facial blemishes were reported by 33.9% (n = 434) and were associated with a positive family history, multiparity, and the use of facial sunscreen (p < 0.0001). The onset or worsening of acne was identified in 35.7% (n = 456) and was statistically associated with primiparity and Fitzpatrick phototypes IV and V. Hair alterations were reported by 44.5% (n = 569) and were associated with primiparity (p = 0.029). CONCLUSION: Although most of the skin changes during pregnancy are considered "physiologic," they can cause significant discomfort. Thus, it is important to know them and to understand which risk factors may be associated with such changes.
Assuntos
Acne Vulgar/etiologia , Dermatoses Faciais/etiologia , Doenças do Cabelo/etiologia , Período Pós-Parto , Acne Vulgar/epidemiologia , Brasil/epidemiologia , Estudos Transversais , Dermatoses Faciais/epidemiologia , Doenças do Cabelo/epidemiologia , Fatores de RiscoRESUMO
Nevus sebaceous of Jadassohn is a congenital hamartoma that usually affects the scalp and face. Several benign or malignant neoplasias may develop in the lesion and the most common are trichoblastoma, syringocystadenoma papilliferum, and basal cell carcinoma. Trichilemmoma is a benign solid tumor originating from external sheath cells of pilosebaceous follicles. When it is characterized by a central zone of desmoplasia, it is called desmoplastic trichilemmoma. We report a case of a 58-year-old patient who developed a tumor in a sebaceous nevus. We performed a total excision of the lesion. Histopathological diagnosis was compatible with desmoplastic trichilemmoma. Our literature review reveals that the occurrence of trichilemmoma desmoplastic is unusual. Moreover, it can mimic an invasive carcinoma on histological and clinical examinations. This fact confirms the importance of reporting the occurrence of this rare cancer in a nevus sebaceous of Jadassohn.
Assuntos
Doenças do Cabelo/etiologia , Doenças do Cabelo/patologia , Folículo Piloso/patologia , Nevo Sebáceo de Jadassohn/complicações , Nevo Sebáceo de Jadassohn/patologia , Carcinoma Basocelular/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Doenças Raras , Couro Cabeludo/patologia , Neoplasias Cutâneas/patologiaRESUMO
Skin manifestations associated with chronic kidney disease are very common. Most of these conditions present in the end stages and may affect the patient's quality of life. Knowledge of these entities can contribute to establishing an accurate diagnosis and prognosis. Severe renal pruritus is associated with increased mortality and a poor prognosis. Nail exploration can provide clues about albumin and urea levels. Nephrogenic systemic fibrosis is a preventable disease associated with gadolinium contrast. Comorbidities, such as diabetes mellitus and secondary hyperparathyroidism, can lead to acquired perforating dermatosis and calciphylaxis, respectively. Effective and innovative treatments are available for all of these conditions.
Assuntos
Insuficiência Renal Crônica/patologia , Dermatopatias/etiologia , Pele/patologia , Calciofilaxia/etiologia , Calciofilaxia/terapia , Comorbidade , Doenças do Cabelo/etiologia , Doenças do Cabelo/patologia , Doenças do Cabelo/terapia , Humanos , Doenças da Unha/etiologia , Doenças da Unha/patologia , Doenças da Unha/terapia , Dermopatia Fibrosante Nefrogênica/etiologia , Dermopatia Fibrosante Nefrogênica/terapia , Porfiria Cutânea Tardia/etiologia , Porfiria Cutânea Tardia/terapia , Prognóstico , Prurido/etiologia , Prurido/terapia , Insuficiência Renal Crônica/complicações , Dermatopatias/diagnóstico , Dermatopatias/patologia , Dermatopatias/terapia , Terapias em EstudoRESUMO
Trichiasis is a lid margin disorder in which the eyelashes are misdirected toward the ocular surface. It is a major cause of ocular morbidity. Trichiasis is secondary to inflammation and scarring of the eyelash follicles. There is a frequent association between trichiasis and cicatricial entropion and the correct diagnosis is mandatory for a successful treatment. There are several options for the management of trichiasis and the main purpose is to eliminate the anomalous cilia and improve the patient's comfort. Temporary measures include eye lubricants, contact lenses, and mechanical epilation. Surgical treatments have initial success but long-term results are poor and recurrences are frequent. Definitive trichiasis treatments include bipolar electrolysis, radiofrequency ablation, cryotherapy and laser ablation, and surgical procedures. The techniques are described in detail along with possible complications and outcome.
Assuntos
Pestanas , Doenças Palpebrais/etiologia , Doenças do Cabelo/etiologia , Doenças Palpebrais/diagnóstico , Doenças Palpebrais/terapia , Doenças do Cabelo/diagnóstico , Doenças do Cabelo/terapia , Humanos , Tracoma/complicaçõesRESUMO
La alopecia es un motivo de preocupación muy frecuente en hombres y mujeres. Desde hace muchos años se ha intentado encontrar, con escaso éxito, un tratamiento eficaz. Este artículo describe las causas y las formas de detectarlas a través del interrogatorio y el examen físico, para poder emplear con seguridad los mejores tratamientos disponibles para el tratamiento de la alopecia androgenética: minoxidil tópico y finasteride oral.
Assuntos
Humanos , Masculino , Feminino , Alopecia/diagnóstico , Alopecia/tratamento farmacológico , Alopecia/terapia , Doenças do Cabelo , Doenças do Cabelo/etiologia , Finasterida/administração & dosagem , Minoxidil/administração & dosagemRESUMO
In this article, the nail, hair, and pigment changes caused by systemic diseases will be reviewed. Among the subjects discussed are abnormalities of shape, attachments, surface, and color of the nails; hair alterations such as telogen and anagen effluvium, scarring alopecia, hypertrichosis, and hirsutism; and pigment changes due to connective tissue disorders, sarcoidosis, and metabolic and endocrinologic diseases, among others.
Assuntos
Doenças do Cabelo/etiologia , Doenças da Unha/etiologia , Transtornos da Pigmentação/etiologia , Feminino , Humanos , MasculinoAssuntos
Cistos/etiologia , Displasia Ectodérmica/complicações , Doenças do Cabelo/etiologia , Adulto , Cistos/tratamento farmacológico , Displasia Ectodérmica/tratamento farmacológico , Etretinato/uso terapêutico , Feminino , Doenças do Cabelo/tratamento farmacológico , Humanos , Ceratolíticos/uso terapêuticoRESUMO
Interaction between neonatal undernutrition and the increased self-grooming activity upon hair growth of several body areas was analyzed in rats of 10, 20 and 30 days of age. Light microscopic observations on methylene blue impregnated hairs showed that these perinatal influences delayed the growth of hair follicles and thickness and length of hair measurements of the head and thoracic areas. The hair growth of lateral abdominal regions was less affected. Data suggest that hair alterations are primarily related to food deprivation since hair follicle measures of all skin areas were more affected than the distal hair measurements. Moreover, the distribution of impaired hair growth on different body areas correlates well with the increased self-grooming components associated to neonatal undernourishment.