RESUMO
THE COMPARISONA and B Axilla of a 65-year-old White man with erythrasma showing a well-demarcated erythematous plaque with fine scale (A). Wood-lamp examination of the area showed characteristic bright coral red fluorescence (B).C and D A well-demarcated, red-brown plaque with fine scale in the antecubital fossa of an obese Hispanic woman (C). Wood-lamp examination revealed bright coral red fluorescence (D).E Hypopigmented patches (with pruritus) in the groin of a Black man. He also had erythrasma between the toes.
Assuntos
Eritrasma , Masculino , Humanos , Eritrasma/diagnóstico , Prurido , VirilhaRESUMO
Este estudio se realizó para caracterizar la frecuencia de aparición, extensión, edad y sexo de la incidencia del eritrasma en pacientes diabéticos según el tipo, la duración y el estado. Estudio transversal y combinado de casos y controles de 200 pacientes diabéticos y 160 grupos no diabéticos que visitaron la consulta externa del Hospital Docente Al-Saddar, Departamento de Medicina y Dermatología, desde el período de diciembre de 2019 a julio de 2020. Dentro del grupo con Diabetes las edades oscilan entre los 12 y los 60 años con una edad media de 37,6 años. 148 pacientes padecían diabetes mellitus tipo no insulinodependiente (NIDDM) y 52 pacientes padecían IDDM. Entre todos los pacientes diabéticos examinados con la lámpara de Wood, para detectar infección por eritrasma, 34 (17%) resultaron afectados, de 26 hombres (76,5% de los afectados) y 8 mujeres (23,5%) se vieron afectados. Entre los 52 pacientes con DMID, 15 (28,8%) se vieron afectados y sólo 19 (12,8%) del resto con DMID se vieron afectados. Se encontró que la incidencia máxima de edad se encuentra en la cuarta década (30-40 años). El sitio de mayor propensión de las lesiones parecía ser la ingle en un 100%. La forma extensa o generalizada se encontró solo en 3 (8,8%) pacientes y el sitio menos afectado fue la membrana de los dedos solo en 2 (5,9%). La presentación de los pacientes fue asintomática en 22 (64,7%) y el cambio de color (marrón rojizo) se encontró en todos los pacientes. En conclusión, la aparición de eritrasma en pacientes diabéticos es más frecuente que su aparición en pacientes no diabéticos. Existe una asociación significativa entre la aparición de eritrasma y la IDDM. La frecuencia de aparición de eritrasma aumenta con la larga duración de la DM y más con la DM incontrolada
This study was conducted to characterize the frequency of occurrence, extent, age, and sex incidence of Erythrasma in diabetic patients according to the type, duration, and state. A cross-sectional and case-control combined study of 200 diabetic patients and 160 non-diabetic groups visiting the outpatient clinic of Al-Saddar Teaching Hospital, Department of Medicine and Dermatology, from the period of December 2019 to July 2020. Among the diabetic group, their ages range from 12-60 years with a mean age of 37.6 years. 148 patients were non-insulin-dependent diabetes mellitus type (NIDDM) and 52 patients were IDDM. Among all the diabetic patients examined by wood's light to detected Erythrasma infection 34(17%) were found to be affected, from 26 males (76.5% of the affected) and 8 females (23.5%) were affected. Among the 52 patients with IDDM, 15(28.8%) were affected and only 19(12.8%) from the remainder with NIDDM affected. The peak age incidence was found to be in the fourth decade (30-40 y). The site of greatest propensity of the lesions appeared to be the groin was 100%. The extensive or generalized form was found only in 3(8.8%) patients and the least affected site was the toe webs only in 2(5.9%). The presentation of the patients was found to be asymptomatic in 22(64.7%), and the color change (red brown) was found in all of the patients. In the conclusion, the occurrence of Erythrasma in diabetic patients is more frequent than its occurrence in non-diabetic patients. There is a significant association between the occurrence of Erythrasma and the IDDM. The frequency of occurrence of Erythrasma increase with the long duration of DM and more with the uncontrolled DM.
Assuntos
Humanos , Adolescente , Adulto , Pessoa de Meia-Idade , Estudos de Casos e Controles , Estudos Transversais/estatística & dados numéricos , Diabetes Mellitus/fisiopatologia , Eritrasma/fisiopatologiaRESUMO
BACKGROUND: Erythrasma is caused by Corinebacterium minutissimum producing a porphyrin that with Wood's light emits a coral-red fluorescence. It is the most common bacterial infection of the feet. Ozonated olive oil decreases the cytoplasm and damages bacterial proteins and lipids. Treatment is with oral erythromycin and there is no consensus regarding the topical therapy of choice. The aim of this paper is to evaluate the therapeutic efficacy of ozonated olive oil in a pilot trial for Erythrasma. METHODS: Experimental, open, observational, descriptive, longitudinal clinical trial at the section of Mycology, of the General Hospital "Dr. Manuel Gea González". PATIENTS: 10 individuals with interdigital feet Erythrasma. INTERVENTION: ozonated olive oil every 12 hours for 10 days was given. RESULTS: All patients had disappearance of coral-red fluorescence, erythema, fissures, pruritus, and maceration; two patients persisted with scaling. A cure was obtained in 100 % of patients, similar to oral erythromycin response. CONCLUSIONS: Ozonated olive oil is a good topical treatment option for interdigital Erythrasma avoiding oral medications. Larger studies are required.
Introducción: el eritrasma es causado por Corinebacterium minutissimum que produce una porfirina que con la luz de Wood emite una fluorescencia rojo coral es la infección bacteriana más frecuente en los pies. El aceite de oliva ozononificado disminuye el citoplasma y daña las proteínas y los lípidos bacterianos. El tratamiento es mediante eritromicina oral y no hay consenso respecto a la terapia tópica de elección. El objetivo de este trabajo es evaluar la eficacia terapéutica del aceite de oliva ozonificado en el eritrasma en una prueba piloto. Métodos: estudio clínico experimental, abierto, observacional, descriptivo y longitudinal, llevado a cabo en la sección de Micología del Hospital General "Dr. Manuel Gea González". Se incluyeron 10 pacientes con eritrasma interdigital de pies, a quines se les administró aceite de oliva ozonificado cada 12 horas por 10 días. Resultados: en todos los pacientes hubo desaparición de la fluorescencia rojo coral, eritema, fisuras, prurito y maceración; en dos de ellos persistió la descamación. Se obtuvo una cura clínica en el 100 % de los pacientes, respuesta similar a la eritromicina oral. Conclusiones: el aceite de oliva ozonificado es una buena opción terapéutica tópica para el eritrasma interdigital, que permite evitar la prescripción de medicamentos por vía oral. Se requieren estudios más extensos.
Assuntos
Eritrasma/tratamento farmacológico , Dermatoses do Pé/tratamento farmacológico , Azeite de Oliva/uso terapêutico , Fitoterapia , Administração Cutânea , Adolescente , Adulto , Idoso , Esquema de Medicação , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Ozônio , Projetos Piloto , Dedos do Pé , Resultado do Tratamento , Adulto JovemRESUMO
Interdigital foot infections are mostly caused initially by dermatophytes, yeasts and less frequently by bacteria. Erythrasma caused by Corynebacterium minutissimum can be confused with superficial mycoses. The aim of the study was to determine the prevalence of the etiologic agents of superficial mycoses and the frequency of Corynebacterium minutissimum in interdigital foot infections. All the samples obtained from the 121 patients with interdigital foot infections were examined directly with the use of 20% potassium hydroxide mounts and Gram stain under the microscope and cultured on Sabouraud's dextrose agar plates. In identification of superficial mycoses, the rate was found to be 14% with the cultural method and 14% with direct microscopic examination. Using a combination of direct microscopic examination and culture, a 33.8% ratio was achieved. In the culture of these samples, the most isolated factor was Trichophyton rubrum (33.7%). In 24 of the patients (19.8%) Corynebacterium minutissimum was detected by Gram staining, in 6 of these patients Trichophyton rubrum was found, Trichophyton mentagrophytes was found in 2 and Trichosporon spp. was found in 1. The examination of interdigital foot lesions in the laboratory, the coexistence of erythrasma with dermatophytes and yeast should be considered.
Assuntos
Arthrodermataceae/isolamento & purificação , Corynebacterium/isolamento & purificação , Dermatomicoses/epidemiologia , Eritrasma/epidemiologia , Doenças do Pé/epidemiologia , Dermatomicoses/microbiologia , Eritrasma/microbiologia , Doenças do Pé/microbiologia , Humanos , Técnicas Microbiológicas , PrevalênciaRESUMO
Interdigital foot infections are mostly caused initially by dermatophytes, yeasts and less frequently by bacteria. Erythrasma caused by Corynebacterium minutissimum can be confused with superficial mycoses. The aim of the study was to determine the prevalence of the etiologic agents of superficial mycoses and the frequency of Corynebacterium minutissimum in interdigital foot infections. All the samples obtained from the 121 patients with interdigital foot infections were examined directly with the use of 20% potassium hydroxide mounts and Gram stain under the microscope and cultured on Sabouraud's dextrose agar plates. In identification of superficial mycoses, the rate was found to be 14% with the cultural method and 14% with direct microscopic examination. Using a combination of direct microscopic examination and culture, a 33.8% ratio was achieved. In the culture of these samples, the most isolated factor was Trichophyton rubrum (33.7%). In 24 of the patients (19.8%) Corynebacterium minutissimum was detected by Gram staining, in 6 of these patients Trichophyton rubrum was found, Trichophyton mentagrophytes was found in 2 and Trichosporon spp. was found in 1. The examination of interdigital foot lesions in the laboratory, the coexistence of erythrasma with dermatophytes and yeast should be considered.
Assuntos
Humanos , Arthrodermataceae/isolamento & purificação , Corynebacterium/isolamento & purificação , Dermatomicoses/epidemiologia , Eritrasma/epidemiologia , Doenças do Pé/epidemiologia , Dermatomicoses/microbiologia , Eritrasma/microbiologia , Doenças do Pé/microbiologia , Técnicas Microbiológicas , PrevalênciaRESUMO
Interdigital foot infections are mostly caused initially by dermatophytes, yeasts and less frequently by bacteria. Erythrasma caused by Corynebacterium minutissimum can be confused with superficial mycoses. The aim of the study was to determine the prevalence of the etiologic agents of superficial mycoses and the frequency of Corynebacterium minutissimum in interdigital foot infections. All the samples obtained from the 121 patients with interdigital foot infections were examined directly with the use of 20% potassium hydroxide mounts and Gram stain under the microscope and cultured on Sabouraud's dextrose agar plates. In identification of superficial mycoses, the rate was found to be 14% with the cultural method and 14% with direct microscopic examination. Using a combination of direct microscopic examination and culture, a 33.8% ratio was achieved. In the culture of these samples, the most isolated factor was Trichophyton rubrum (33.7%). In 24 of the patients (19.8%) Corynebacterium minutissimum was detected by Gram staining, in 6 of these patients Trichophyton rubrum was found, Trichophyton mentagrophytes was found in 2 and Trichosporon spp. was found in 1. The examination of interdigital foot lesions in the laboratory, the coexistence of erythrasma with dermatophytes and yeast should be considered.
Assuntos
Humanos , Arthrodermataceae/isolamento & purificação , Corynebacterium/isolamento & purificação , Dermatomicoses/epidemiologia , Eritrasma/epidemiologia , Doenças do Pé/epidemiologia , Dermatomicoses/microbiologia , Eritrasma/microbiologia , Doenças do Pé/microbiologia , Técnicas Microbiológicas , PrevalênciaRESUMO
BACKGROUND: Erythrasma is a superficial infection caused by Corynebacterium minutissimum and affects the major skin folds and the interdigital regions of the feet. It is characterized by erythematous, brown, scaly patches and maceration, and exhibits coral-red fluorescence under Wood light. OBJECTIVE: The aim of this study was to determine the frequency of erythrasma in patients with interdigital lesions. METHODS: An open, prospective, longitudinal, observational study was performed in a hospital in Mexico City between March and December, 2006. All patients with interdigital lesions were examined with a Wood lamp and direct examination was performed with 20 % potassium hydroxide. Cultures were done in Sabouraud dextrose agar and brain heart infusion agar, and smears were analyzed. General characteristics and concomitant diseases were recorded. RESULTS: We examined 73 patients, of whom 24 (32.8 %) were diagnosed with erythrasma based on coral-red fluorescence under Wood light and identification of corynebacteria by Gram staining. The disease was more common in women (83.33 %) and the mean age of the patients was 43.5 years. The main clinical findings were scaling and maceration, and the fourth interdigital web was the most commonly affected. Corynebacterium could not be isolated in any of the cases. Mycology was positive in 15 cases (62.5 %) and the following microorganisms were isolated: Candida (16.6 %), dermatophytes (12.5 %), and Trichosporon (4.1 %). CONCLUSIONS: Interdigital erythrasma is a common condition and can be easily confused with interdigital tinea. It persists if not treated appropriately. Rapid diagnosis is easily obtained by examination with a Wood lamp, while culture is difficult and unnecessary for diagnosis. The coexistence of erythrasma with dermatophytes and Candida should be considered when the interdigital webs are affected.
Assuntos
Dermatomicoses/epidemiologia , Eritrasma/epidemiologia , Dermatoses do Pé/epidemiologia , Dermatoses da Mão/epidemiologia , Adolescente , Adulto , Idoso , Infecções por Corynebacterium/diagnóstico , Estudos Transversais , Dermatomicoses/diagnóstico , Dermatomicoses/microbiologia , Dermatomicoses/patologia , Diagnóstico Diferencial , Eritrasma/diagnóstico , Eritrasma/microbiologia , Eritrasma/patologia , Feminino , Fluorometria , Dermatoses do Pé/diagnóstico , Dermatoses do Pé/microbiologia , Dermatoses do Pé/patologia , Dermatoses da Mão/diagnóstico , Dermatoses da Mão/microbiologia , Dermatoses da Mão/patologia , Humanos , Estudos Longitudinais , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Prevalência , Estudos Prospectivos , População UrbanaRESUMO
El eritrasma es una infección superficial de la piel que afecta la capa córnea y es causado por una bacteria grampositiva, Corynebacterium minutissimum. Se presenta como manchas eritematosas a marrón en grandes pliegues y como descamación y maceración en pliegues interdigitales; es asintomática, aunque en algunos casos se acompaña de prurito. El diagnóstico es clínico por luz de Wood que da una fluorescencia rojo coral de las áreas afectadas. Su curso es benigno, aunque persiste si no se da un tratamiento adecuado.
Erythrasma is a superficial skin infection of the stratum corneum caused by a gram-positive bacteria, Corynebacterium minutissimum. It is characterized by reddish-brown areas affecting occluded intertriginous zones such as axillae, inframammary folds, and as irregular scaly patches or macerated lesions on toeweb spaces. It is asymptomatic, though sometimes accompanied by pruritus. Clinical diagnosis is supported by a red fluorescence under Wood s light examination. It is benign, yet persistent if not adequately treated.
Assuntos
Humanos , Eritrasma/diagnóstico , Eritrasma/terapia , Diagnóstico Diferencial , Eritrasma/epidemiologia , Eritrasma/microbiologia , Infecções por Corynebacterium/complicações , PrognósticoRESUMO
Lesoes cutaneas interdigitais sao frequentes em pacientes com linfedema de membros e sua prevencao e tratamento sao importantes no controle da doenca e prevencao de complicacoes infecciosas. Material colhido da regiao interpododigital de 21 pacientes com linfedema dos membros inferiores do Ambulatorio da Unidade de Linfedema do Servico de Cirurgia Vascular do Hospital das Clinicas da FMUSP foram estudados atraves de exame micologico direto, cultura para fungos e exame direto por luz fluorescente. Treze dos pacientes apresentaram lesoes clinicas sugestivas de intertrigo (61,9 por cento). Em 11 destes pacientes, demonstrou-se presenca exclusiva de fungos em sete pacientes, Corynebacterium minutissimum em dois e associacao de fungos e bacterias em outros dois pacientes...