RESUMO
The consumption and sharing of information on social media contribute to the circulation of false health content. In this sense, popular belief-driven posts recommending the use of amber necklaces to prevent symptoms of teething can be easily found on social media, even when they offer health risks for children. Accordingly, this study aimed to characterize posts in Portuguese by identifying message-based factors associated with higher user interactions of Facebook. A total of 500 Facebook posts published in Portuguese between August 2016 and August 2021 were retrieved by CrowdTangle, and analyzed quantitatively according to time of publication, total user interaction, and post overperforming score, and then qualitatively by two independent investigators, according to motivation, authors' profiles, and sentiment. The data were evaluated by descriptive analysis, Mann-Whitney U test, chi-square test, and multiple logistic regression models regarding interaction metrics. The posts were published predominantly by commercial profiles, with social, psychological, and financial motivations, and expressed positive sentiment. Furthermore, time of publication (OR=2.65), regular user profiles (OR=3.30), and neutral/negative sentiment (OR=2.76) were associated positively with total interactions, whereas only time of publication was associated with post overperforming scores (OR=1.65). In conclusion, Facebook posts promoting efficacy of amber necklaces in managing teething symptoms are primarily created by commercial profiles with vested interests in marketing the product. The key factors that contribute to the success of posts containing false information about amber necklaces on Facebook can be identified by considering the author's profile, sentiment, and time of publication.
Assuntos
Mídias Sociais , Humanos , Erupção Dentária/fisiologia , Estatísticas não Paramétricas , Fatores de Tempo , Modelos Logísticos , Disseminação de Informação/métodos , Portugal , MotivaçãoRESUMO
Purpose: To evaluate the chronology of the eruption of primary mandibular central incisors in infants born preterm and with low weight (PLBW) and its association with weight/length ratio for gestational age (GA) at birth, individual characteristics and hospitalization at birth. Methods: A cohort of 46 infants was followed at a multidisciplinary reference center at a university hospital in Belo Horizonte, Brazil. The inclusion criteria were infants born preterm with low/very low/extreme low birth weight and at least four months of age. Oral clinical examinations were carried out by a calibrated dentist for a total of eight months, with a one-month interval between each examination, to verify the chrono- logy of eruption of the primary mandibular central incisors. Caregivers completed a sociodemographic and health questionnaire. Data on neonatal hospitalization were collected from medical records. Data were analyzed with the Kaplan-Meier method and log rank test, and bivariate analysis was done using the Mann-Whitney method and Kruskal-Wallis test (P <0.05). Results: The average age at eruption of primary lower central incisors was 11 months for both sexes. No association was found between tooth eruption and child hospitalization or individual characteristics (P >0.05). Infants large for gestational age had earlier tooth eruption (9.3±1.41 months) than infants small for gestational age (13.6±3.29 months; P <0.05).Conclusion: The most likely age for the eruption of the first primary teeth in infants born preterm and with low weight was 11 months, and there was no influence of individual characteristics and hospitalization at birth. Small-for-gestational age infants experienced delayed tooth eruption compared to large-for-GA infants.
Assuntos
Incisivo , Recém-Nascido Prematuro , Recém-Nascido Pequeno para a Idade Gestacional , Erupção Dentária , Humanos , Erupção Dentária/fisiologia , Masculino , Feminino , Lactente , Recém-Nascido , Brasil , Estudos de Coortes , Dente Decíduo , Mandíbula , Idade Gestacional , Recém-Nascido de Baixo Peso , HospitalizaçãoRESUMO
OBJECTIVES: To assess the influence of estrogen deficiency on tooth eruption rate (TER) and gene expression of estrogen receptor alpha and beta (ERα and ERß) in the odontogenic region of teeth with continuous formation in a rat model. MATERIALS AND METHODS: Ovariectomies (OVX; n = 25) and sham surgeries (SHAM; n = 25) were performed in female Wistar rats when animals were 25 days old. The TER of the lower incisors, both in impeded (hyperfunction condition) and unimpeded (trimmed incisal edge-hypofunction condition) conditions, was evaluated using standardized digital photographs acquired every 48-72 h for 3 weeks (35th-53rd day of life), using a camera coupled to a stereomicroscope. Quantitative real-time PCR was performed to evaluate the relative gene expression of ERα and ERß in the odontogenic region. RESULTS: The OVX group showed a significant reduction in TER when compared to the SHAM group, only in the impeded condition (p = 0.03). There was no statistically significant difference between the groups in ERα gene expression (p = 0.33). ERß showed a significantly higher gene expression in the OVX group (p ≤ 0.05). CONCLUSIONS: Estrogen deficiency decreases TER in teeth under impeded condition. Estrogen deficiency also increases ERß gene expression in the odontogenic region of teeth with continuous formation. CLINICAL RELEVANCE: Hormonal disturbances affecting estrogen levels can cause alterations in dental formation and teeth eruption.
Assuntos
Anormalidades Dentárias , Erupção Dentária , Ratos , Animais , Feminino , Humanos , Erupção Dentária/fisiologia , Ratos Wistar , Receptor alfa de Estrogênio , Incisivo , Receptor beta de Estrogênio/genética , Estrogênios , Receptores de Estrogênio , OvariectomiaRESUMO
Dental follicles are involved in odontogenesis, periodontogenesis, and tooth eruption. Dental follicles are unique structures, considering that their remnants can persist within the jawbones after odontogenesis throughout life if the tooth does not erupt. Pathological changes may occur in these tissues as individuals age. The changes range from benign to life threatening. Thus, the assessment of age-related changes in dental follicles associated with unerupted teeth is of paramount importance. In this review, we summarize the physiological roles and changes in dental follicles in odontogenesis, tooth eruption, and aging, in addition to the pathological changes associated with these structures. We encourage investigators to consider this peculiar tissue as a unique model and explore its potential to clarify its importance from the viewpoints of developmental biology, tissue physiology, and pathology.
Assuntos
Dente Impactado , Dente não Erupcionado , Saco Dentário , Humanos , Odontogênese , Erupção Dentária/fisiologiaRESUMO
El objetivo del presente trabajo es describir las técnicas para el diagnóstico y tratamiento de 3 casos clínicos de odontoma en pacientes ortodóncicos. En el caso 1, se trató a un paciente masculino de 17 años, que acudió para interconsulta con el servicio de ortodoncia, ya que no había erupcionado el canino superior izquierdo y el primer premolar superior izquierdo. El estudio anatomopatológico reveló odontoma complejo con áreas pindborgoides y acumulación de células fantasma. En al caso 2 se trató a un paciente femenino de 15 años. El estudio anatomopatológico reveló odontoma complejo. En el caso 3, se trató a un paciente masculino de 28 años que acudió a rehabilitación integral de su boca, y fue derivado a la cátedra de ortodoncia. En la radiografía panorámica se observó una imagen compatible con odontoma. Se remitió una muestra a anatomía patológica que confirmó el diagnóstico de odontoma. Conclusión: el conocimiento adecuado de las características clínicas, radiológicas y patológicas es necesario para un correcto diagnóstico y tratamiento. Es importante el trabajo interdisciplinario ortodoncista - cirujano para tratar estos casos (AU)
The objective of this work is to describe the techniques for the diagnosis and treatment of 3 clinical cases of odontoma in orthodontic patients. In case 1, a 17-year-old male patient was treated who came for consultation with the orthodontic service, since the upper left canine and the upper left first premolar had not erupted. Pathological study revealed complex odontoma with pindborgoid areas and accumulation of ghost cells. In case 2, a 15-year-old female patient was treated. The anatomopathological study revealed a complex odontoma. In case 3, a 28-year-old male patient was treated who attended comprehensive rehabilitation of his mouth and was referred to the orthodontic department. In the panoramic radiography, an image compatible with odontoma was observed. A sample was sent to pathological anatomy, which confirmed the diagnosis of odontoma. Conclusion: Adequate knowledge of the clinical, radiological and pathological characteristics is necessary for a correct diagnosis and treatment. Interdisciplinary orthodontist-surgeon work is important to treat these cases (AU)
Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Equipe de Assistência ao Paciente , Odontoma/cirurgia , Odontoma/diagnóstico , Odontoma/terapia , Ortodontia Corretiva/métodos , Argentina , Faculdades de Odontologia , Erupção Dentária/fisiologia , Dente não Erupcionado/fisiopatologia , Radiografia Panorâmica/métodos , Tumores Odontogênicos/classificação , Odontoma/diagnóstico por imagem , Técnicas HistológicasRESUMO
In the last decades, several discoveries have uncovered the complexity of mammalian evolution during the Mesozoic Era, including important Gondwanan lineages: the australosphenidans, gondwanatherians, and meridiolestidans (Dryolestoidea). Most often, their presence and diversity is documented by isolated teeth and jaws. Here, we describe a new meridiolestidan mammal, Orretherium tzen gen. et sp. nov., from the Late Cretaceous of southern Chile, based on a partial jaw with five cheek teeth in locis and an isolated upper premolar. Phylogenetic analysis places Orretherium as the earliest divergence within Mesungulatidae, before other forms such as the Late Cretaceous Mesungulatum and Coloniatherium, and the early Paleocene Peligrotherium. The in loco tooth sequence (last two premolars and three molars) is the first recovered for a Cretaceous taxon in this family and suggests that reconstructed tooth sequences for other Mesozoic mesungulatids may include more than one species. Tooth eruption and replacement show that molar eruption in mesungulatids is heterochronically delayed with regard to basal dryolestoids, with therian-like simultaneous eruption of the last premolar and last molar. Meridiolestidans seem endemic to Patagonia, but given their diversity and abundance, and the similarity of vertebrate faunas in other regions of Gondwana, they may yet be discovered in other continents.
Assuntos
Arcada Osseodentária/anatomia & histologia , Mamíferos/classificação , Dente/anatomia & histologia , Animais , Dente Pré-Molar/anatomia & histologia , Evolução Biológica , Osso e Ossos/anatomia & histologia , Chile , Fósseis/história , História Antiga , Dente Molar/anatomia & histologia , Filogenia , Crânio/anatomia & histologia , Anormalidades Dentárias/classificação , Erupção Dentária/fisiologiaRESUMO
OBJECTIVES: To determine whether early diet and weight gain velocity have independent or interactive effects on deciduous teeth emergence and overweight status during the first year. STUDY DESIGN: Monthly measures of anthropometry and teeth eruption were collected during a 1-year trial (0.5-12.5 months) on formula-fed infants in which the type of randomized infant formula (cow milk or extensively hydrolyzed protein) diet significantly affected early (0.5-4.5 months) weight gain velocity. Generalized linear mixed models determined whether early diet and weight gain velocity had independent or interactive effects on timing and pattern of teeth eruption. Data from a trial on breastfed infants were used to explore effects of breast milk vs infant formula diets on teeth eruption and overweight status at 10.5 months. RESULTS: Independent of infant formula diet, velocities of weight gain had direct effects on the age of first deciduous tooth (P < .04) and number of erupted teeth over time (P < .002). Greater velocity of weight gain from 0.5 to 4.5 months caused earlier and more frequent eruption of deciduous teeth from 4.5 to 12.5 months. Exploratory follow-up analyses on the breastfed and formula-fed diet groups found early weight gain velocity (P = .001), but not diet or its interaction, had significant effects. Infants in the upper quartile for weight gain velocity had more primary teeth (P = .002), and a greater proportion of them were overweight (P < .001) at 10.5 months. CONCLUSIONS: Faster weight gain accretion forecasted accelerated primary teeth eruption and increased percentage of children who were overweight-risk factors for dental caries and obesity. TRIAL REGISTRATION: ClinicalTrials.govNCT01700205 [2012-2015] and NCT01667549 [2012-2015].
Assuntos
Desenvolvimento Infantil , Obesidade Infantil/metabolismo , Erupção Dentária/fisiologia , Aumento de Peso/fisiologia , Feminino , Humanos , Lactente , Fórmulas Infantis , Fenômenos Fisiológicos da Nutrição do Lactente/fisiologia , MasculinoRESUMO
RESUMEN: Uno de los problemas con mayores consecuencias tanto estéticas como funcionales en ortodoncia es la impactación de caninos maxilares (ICM) siendo principal motivo de reabsorciones radiculares de dientes adyacentes. Actualmente se carece de estudios que describan la reabsorción radicular por ICM a través de tomografía computarizada conebeam (TCCB) en la población chilena. El objetivo del estudio fue describir a pacientes entre 8 a 18 años, que presentan ICM (o riesgo de ella), tanto en las características de la impactación canina como en la reabsorción radicular presentada en incisivos laterales (IL) y en otros dientes adyacentes. En este estudio retrospectivo, 135 datos de TCCB fueron seleccionados por conveniencia, de los cuales 181 caninos presentaron ICM. Fueron analizadas las variables edad, sexo, tipo de ICM (unilateral o bilateral), localización bucolingual (vestibular o palatino), lado de impactación (derecho o izquierdo), reabsorción radicular en el incisivo lateral y registro de el o los dientes anexos afectados por reabsorción radicular (incisivo central y/o premolares). Además en el caso de reabsorción de IL fue analizada la reabsorción tridimensionalmente a través de la ThreeDimensional Leeds Orthodontic Root Resorption Target Scale (3D-LORTS). La ICM en la muestra seleccionada tuvo una edad promedio de 12 años, una relación por sexo mujeres:hombres de 1,5:1, frecuentemente de tipo unilateral, en el lado derecho y una localización bucolingual palatina (64,1 %) por sobre la vestibular (35,9 %). La reabsorción radicular alcanzó un 35,9 %, de la cual un 27,6 % involucró a IL y un 8,3 % en dientes anexos adyacentes. En cuanto a la distribución tridimensional de la reabsorción radicular, la más frecuente involucró el tercio apical (60 %), con compromiso pulpar o severo (40 %), involucrando solo una cara, la palatina (54 %). Ninguna de las variables anteriores consideradas, demostró diferencias estadísticas con la reabsorción radicular de incisivos laterales.
ABSTRACT: One of the problems with greatest aesthetic and functional consequences in orthodontics is the Impaction of Maxillary Canines (ICM) being the main reason for root resorption of the adjacent teeth. Currently there are no studies describing root resorption by ICM through cone beam computed tomography (CBCT) in the Chilean population. The main objective of the study was to describe patients between 8 and 18 years old, who presented with ICM (or risk thereof), with the characteristics of canine impaction as well as root resorption presented in lateral incisors (IL) and in other adjacent teeth. In this retrospective study, 135 CBCT subjects were selected for convenience, of which 181 canines presented ICM. The variables were analyzed: age, sex, type of ICM (unilateral or bilateral), buccolingual location (vestibular or palatal), side of impaction (right or left), root resorption in the lateral incisor and registration of adjacent teeth affected by resorption radicular (central incisor and/or premolars). In addition, when reabsorption of IL was observed, three-dimensional analysis was made using the Three-Dimensional Leeds Orthodontic Root Resorption Target Scale (3D-LORTS). The ICM in the selected sample had an average age of 12 years, a ratio by sex of women:men of 1.5:1, frequently of unilateral type, on the right side and with palatine buccolingual location (64.1 %) above the vestibular (35.9 %). Root resorption reached 35.9 %, of which 27.6 % presented in the IL and 8.3 % in adjacent teeth. Regarding the three-dimensional distribution of root resorption, the most frequent involved the apical third (60 %), with pulpal or severe damage (40 %), in only one location, the palatine (54 %). None of the above variables considered showed statistical differences with the root resorption of lateral incisors.
Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Dente Impactado/etiologia , Dente Canino/patologia , Reabsorção da Raiz , Erupção Dentária/fisiologia , Chile , Estudos Retrospectivos , Imageamento Tridimensional , Distribuição por Idade e Sexo , Tomografia Computadorizada de Feixe Cônico/métodosRESUMO
ABSTRACT: Tooth eruption requires resorption of the alveolar bone interposed between the tooth germ and the oral mucosa (coronal bone). The cells responsible for bone resorption are the osteoclasts and their activity can be reduced or inactivated by estrogen hormone. We aimed to investigate the effects of estrogen on the process of tooth eruption in rats. Thirty-three Wistar rats, aged two-to-17-days, were divided into control, sham and estrogen-treated groups. After daily injections with estrogen, the animals were euthanized and the jaws removed and processed for histological analysis. We performed clinical examination, morphological analysis, quantification of the number of osteoclasts on the surface of the coronal bone and immunohistochemical analysis of estrogen receptor type alpha (ERα). Estrogen therapy was effective, which could be confirmed by the higher estrogen plasma levels on treated animals. However, it had no effect on tooth development or tooth eruption. Progressive bone resorption was observed and the number of osteoclasts on coronal bone was not affected on hormoneinjected animals, allowing tooth to erupt at the same time observed in untreated animals. Immunohistochemistry for ERα confirmed the presence of this type of receptor in osteoclasts, osteoblasts and osteocytes. Taken together, our results showed that estrogen stimulation was not sufficient to decrease the number of osteoclasts on the coronal bone, supporting the idea that, although estrogen may have a protective activity on bone resorption, this may not apply to the alveolar bone that is meant to be resorbed during eruptive process.
RESUMEN: La erupción dental requiere la resorción del hueso alveolar interpuesto entre el germen dental y la mucosa oral (hueso coronal). Las células responsables de la resorción ósea son los osteoclastos y su actividad puede reducirse o inactivarse por la hormona del estrógeno. Objetivos: apuntamos a investigar los efectos del estrógeno en el proceso de la erupción dental en ratas. Treinta y tres ratas Wistar, de dos a 17 días de edad, se dividieron en grupos de control, Sham y se trataron con estrógenos. Los animales fueron eutanizados después del tratamento con estrógeno y se procesaron las mandíbulas para el análisis histológico. Se realizó el examen clínico, el análisis morfológico, la cuantificación del número de osteoclastos en la superficie del hueso coronal y el análisis inmunohistoquímico del tipo de receptor de estrógeno alfa (ERα). La terapia de estrógeno fue eficaz, lo que podría ser confirmado por los niveles plasmáticos más altos de estrógeno en los animales tratados. Sin embargo, no se observó ningún efecto sobre el desarrollo de los dientes o la erupción dental. Se observó una resorción ósea progresiva y el número de osteoclastos en el hueso coronal no se vio afectado en los animales inyectados con hormonas, permitiendo que el diente erupcionó durante el mismo período de tiempo observado en animales no tratados. La inmunohistoquímica para el ERα confirmó la presencia de este tipo de receptor en los osteoclastos, osteoblastos y osteocitos. Nuestros resultados mostraron que la estimulación del estrógeno no fue suficiente para reducir el número de osteoclastos en el hueso coronal confirmando que, si bien el estrógeno puede tener una actividad protectora en la resorción ósea, esto puede no se aplica al hueso alveolar que está destinado a ser rerecurrido durante el proceso eruptivo.
Assuntos
Animais , Feminino , Ratos , Erupção Dentária/fisiologia , Reabsorção Óssea/fisiopatologia , Receptores de Estrogênio , Remodelação Óssea/fisiologia , Experimentação Animal , Osteoclastos , Imuno-Histoquímica/métodos , Comissão de Ética , Ratos Wistar , Estradiol/farmacologia , Estrogênios/administração & dosagem , Estrogênios/efeitos adversos , Estrogênios/uso terapêutico , Processo Alveolar/fisiologiaRESUMO
OBJECTIVE: The aim of this study was to investigate possible malformations in the soft, bone and/or dental tissues in patients with congenital Zika Virus (ZIKV) by clinical and x-ray evaluation. METHODOLOGY: Thirty children born with ZIKV and 30 children born without ZIKV (control group) were included in the study. Patients were evaluated over 24 consecutive months according to the variables: sex, age, cleft palates, soft tissue lesions, alveolar ridge hyperplasia, short labial and lingual frenums, inadequate posture of the lingual and perioral muscles at rest, micrognathia, narrow palatine vaults, changes in the teeth shape and/or number, sequence eruption, spasms, seizures and eruption delay were evaluated. Chi-square test, Student's t-test and nominal logistic regression were used (p<0.05). RESULTS: Among the 30 babies examined, the mean age of the first dental eruption was 10.8±3.8 with almost two-thirds of the children (n=18, 60%) experiencing eruptions of their first tooth after 9 months of age, nine children (30%) had inadequate lingual posture at rest, more than half of the children (n=18, 60%) had short labial or lingual frenums. ZIKV babies showed a high prevalence of clef palate (p<0.001), inadequate lingual posture at rest (p=0.004), micrognathia (p=0.002), changes in the shape and/or number of teeth (p=0.006), alteration in sequence of dental eruption (p<0.001) and muscles spasms (p=0.002). The delay eruption was associated with inadequate lingual posture at rest (p=0.047), micrognathia (p=0.002) and changes in the shape and/or number of teeth (p=0.021). The delayed eruption (p=0.006) and narrow palatine vaults (p=0.008) were independently associated with ZIKV. Moreover, female patients showed the most narrow palatine vaults (p=0.010). CONCLUSIONS: The children with ZIKV showed a greater tendency to have delayed eruption of the first deciduous tooth, inadequate lingual posture and short labial and lingual frenums.