RESUMO
This study evaluated the effect of cobiotic (CO) composed of organic fructans powder of Agave tequilana and turmeric powder of Curcuma longa L. as an alternative of antibiotic growth promoters (AGPs) on growth performance, blood parameters, intestinal pH, oxidative stress, and cytokines serum levels of broiler chickens. A total of 135 one-day-old Ross 308 broilers distributed to five experimental groups, which included starter or finisher standard diets without AGPs (CON), CON + 0.25 COLI-ZIN g/kg feed (AGP), CON + 0.1 g Agave fructans/kg feed (AF), CON + 0.5 g turmeric powder/kg feed (TP) and CON + 0.1 g AF + 0.5 g TP /kg feed (CO), for 49 days. AF followed by TP, decreased feed intake, obtaining the best FCR. AGP increased the heterophil-lymphocyte ratio compared to other groups. CO significantly decreased the pH of the cecal content. AF increased IL-10 levels, while TP decreased it. AF decreased the IL-1ß levels. The present study showed that including a cobiotic based on AF and TP or components separately in a broilers diet improved growth performance, modified intestinal and cecum pH, and stimulated the immune system, which suggests CO as a safe alternative to AGP.
Assuntos
Agave , Ração Animal , Galinhas , Dieta , Suplementos Nutricionais , Frutanos , Estresse Oxidativo , Animais , Galinhas/crescimento & desenvolvimento , Galinhas/imunologia , Galinhas/sangue , Frutanos/administração & dosagem , Frutanos/farmacologia , Ração Animal/análise , Suplementos Nutricionais/análise , Estresse Oxidativo/efeitos dos fármacos , Agave/química , Dieta/veterinária , Citocinas/sangue , Citocinas/metabolismo , Masculino , Curcuma/química , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacosRESUMO
1. This study was conducted to assess the effects of different dietary omega 6:3 ratios fed to male and female Japanese quail breeders on incubation performance, chick quality and progeny performance.2. A completely randomised design was used, with five diets containing different ratios of vegetable oils rich in linoleic acid (LA from soybean oil) or α-linolenic acid (ALA from linseed oil) with LA/ALA ratios of 13.75:1, 10.69:1, 7.63:1, 4.57:1 and 1.48:1 with 12 cage replicates containing six birds each.3. There was a quadratic effect of the LA/ALA ratio on total hatchability (p < 0.011), fertile hatchability (p = 0.046) and total mortality (p = 0.046). There was no effect on fertility (p > 0.05). The LA/ALA ratios of 1.48 and 13.75 fed to both hens and cockerels or hens resulted in greater fertility, as measured by the number of days after copulation during which fertile eggs were laid and the number of points of hydrolysis on the perivitelline membrane. A decreasing linear effect (p < 0.0001) was observed on chick length and an increasing linear effect on body weight at 1 day of age. There were no effects on progeny performance.4. The LA/ALA ratio affected yolk mineral matter (p = 0.009), crude protein (p = 0.091), chick mineral matter (p < 0.038) and ether extract (p < 0.0001) contents. Maternal diet affected the fatty acid profile of egg yolk and chick liver, indicating that dietary contents were transferred to eggs and chicks.5. Fertile egg production increased with lower LA/ALA ratios. Therefore, linseed oil can be used together with soybean oil to formulate diets for female Japanese quail obtain LA/ALA ratios between 4:1 and 10:1.
Assuntos
Ração Animal , Coturnix , Dieta , Ácido Linoleico , Reprodução , Ácido alfa-Linolênico , Animais , Coturnix/fisiologia , Feminino , Dieta/veterinária , Ração Animal/análise , Ácido alfa-Linolênico/administração & dosagem , Ácido alfa-Linolênico/análise , Masculino , Reprodução/efeitos dos fármacos , Ácido Linoleico/administração & dosagem , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , Distribuição Aleatória , Óleo de Semente do Linho/administração & dosagem , Fertilidade/efeitos dos fármacos , Suplementos Nutricionais/análiseRESUMO
In the last few years, there has been a growing interest in the use of natural feed additives in animal feed. These can be used as replacements for antibiotics, to alter rumen fermentation and increase feed efficiency in ruminants. Therefore, the objective of this study is to evaluate the effects of adding different feed additives in the diet of beef and dairy cattle on their performance, dry matter intake (DMI) and feed efficiency, through a systematic review followed by meta-analysis. The systematic review suggested 43 peer-reviewed publications, according to the pre-established criteria. In beef cattle, the ionophore antibiotics reduced the DMI, improved the feed efficiency without interfering in the average daily gain (ADG). Non-ionophore antibiotics and propolis extract increased the ADG. In dairy cattle, the ionophores, yeast-based additives, and enzyme additives increased the feed efficiency, DMI, and daily milk production (MY), respectively. Essential oil supplementation in beef and dairy cattle had no effect on the feed intake and animal performance. The systematic review and meta-analysis allowed us to conclude that different feed additives have different effects on cattle performance, however, our results suggest that there are a few gaps regarding their effects on animal performance.
Assuntos
Ração Animal , Bovinos , Animais , Ração Animal/análise , Suplementos Nutricionais , Ingestão de Alimentos/efeitos dos fármacos , Ingestão de Alimentos/fisiologia , Aditivos Alimentares/administração & dosagem , Aditivos Alimentares/farmacologia , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacosRESUMO
1. The objective of this study was to determine the nutritional and energy values of four maize distiller's dried grains with solubles (DDGS) and one maize high protein distiller's dried grains (HP-DDG) from ethanol production plants in Brazil; to evaluate the digestibility, performance, nitrogen balance and energy values for broiler chickens fed diets containing these coproducts (Experiment I); and to evaluate the effects of xylanase inclusion in diets containing maize DDGS for broilers on energy availability, digestibility, nitrogen balance and gastrointestinal morphometry (Experiment II).2. For each experiment, 180 broiler chickens aged 17 and 30 days with initial weights of 450 ± 18 g and 1228 ± 33 g, respectively, were used; the chickens were distributed into 36 metabolism cages. The experimental design consisted of complete randomised blocks, with six replications per treatment and five birds per experimental unit. The treatments consisted of a basal diet (BD) and five test diets containing maize ethanol coproducts (Experiment I) one BD and five test diets containing DDGS with inclusions of 0, 8,000, 16,000, 24,000 and 32,000 BXU/kg xylanase (Experiment II). In Experiment I, HP-DDG and DDGS2 presented higher AME and AMEn values (14.1 and 13.9 MJ/kg and 13.4 and 13.3 MJ/kg, respectively), than did the other coproducts (p < 0.05). Compared with DDGS1 and DDGS3, DDGS4 and HP-DDG had higher digestible CP values (p < 0.05). In Experiment II, the inclusion of the enzyme quadratically affected the values of digestible CP and digestible EE (p < 0.05), with the maximum values occurring with the inclusion of 18 750 and 22,170 BXU/kg of xylanase, respectively.3. The digestible NDF and digestible MM values linearly increased with the inclusion of xylanase (p < 0.05). The addition of xylanase had no effect on gastrointestinal morphometry (p > 0.05). It was concluded that the inclusion of between 18,000 and 22,000 BXU/kg of xylanase resulted in better digestible CP and digestible EE values.
Assuntos
Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Galinhas , Dieta , Digestão , Endo-1,4-beta-Xilanases , Zea mays , Animais , Galinhas/fisiologia , Galinhas/metabolismo , Zea mays/química , Ração Animal/análise , Digestão/efeitos dos fármacos , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , Dieta/veterinária , Endo-1,4-beta-Xilanases/metabolismo , Endo-1,4-beta-Xilanases/administração & dosagem , Masculino , Distribuição Aleatória , Etanol , Valor Nutritivo , Trato Gastrointestinal/metabolismo , Suplementos Nutricionais/análiseRESUMO
Incorporating Curcumin into animal diets holds significant promise for enhancing both animal health and productivity, with demonstrated positive impacts on antioxidant activity, anti-microbial responses. Therefore, this study aimed to determine whether adding Curcumin to the diet of dairy calves would influence ruminal fermentation, hematologic, immunological, oxidative, and metabolism variables. Fourteen Jersey calves were divided into a control group (GCON) and a treatment group (GTRA). The animals in the GTRA received a diet containing 65.1 mg/kg of dry matter (DM) Curcumin (74% purity) for an experimental period of 90 days. Blood samples were collected on days 0, 15, 45, and 90. Serum levels of total protein and globulins were higher in the GTRA group (P < 0.05) than the GCON group. In the GTRA group, there was a reduction in pro-inflammatory cytokines (IL-1ß and IL-6) (P < 0.05) and an increase in IL-10 (which acts on anti-inflammatory responses) (P < 0.05) when compared to the GCON. There was a significantly higher (P < 0.05) concentration of immunoglobulin A (IgA) in the serum of the GTRA than the GCON. A Treatment × Day interaction was observed for haptoglobin levels, which were higher on day 90 in animals that consumed Curcumin than the GCON (P < 0.05). The catalase and superoxide dismutase activities were significantly higher (P < 0.05) in GTRA, reducing lipid peroxidation when compared to the GCONT. Hematologic variables did not differ significantly between groups. Among the metabolic variables, only urea was higher in the GTRA group when compared to the GCON. Body weight and feed efficiency did not differ between groups (meaning the percentage of apparent digestibility of dry matter, crude protein, and acid detergent fiber (ADF) and neutral detergent fiber (NDF). There was a tendency (P = 0.09) for treatment effect and a treatment x day interaction (P = 0.05) for levels of short-chain fatty acids in rumen fluid, being lower in animals that consumed curcumin. There was a treatment vs. day interaction (P < 0.05) for the concentration of acetate in the rumen fluid (i.e., on day 45, had a reduction in acetate; on day 90, values were higher in the GTRA group when compared to the GCON). We conclude that there was no evidence in the results from this preliminary trial that Curcumin in the diet of dairy calves interfered with feed digestibility. Curcumin may have potential antioxidant, anti-inflammatory, and immune effects that may be desirable for the production system of dairy calves.
Assuntos
Ração Animal , Curcumina , Dieta , Suplementos Nutricionais , Fermentação , Rúmen , Animais , Curcumina/administração & dosagem , Curcumina/farmacologia , Rúmen/metabolismo , Rúmen/efeitos dos fármacos , Bovinos , Ração Animal/análise , Dieta/veterinária , Suplementos Nutricionais/análise , Estresse Oxidativo/efeitos dos fármacos , Masculino , Citocinas/metabolismo , Desmame , Antioxidantes/metabolismo , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , FemininoRESUMO
Low crude protein (CP) diets can reduce nitrogen (N) excretion and costs by increasing N utilization efficiency. Exogenous proteases may further improve protein digestibility in low CP diets. This study first evaluated in vitro the efficacy of a multiprotease on amino acid (AA) release from feedstuffs and broiler feed. Later, a broiler study evaluated the effect of feeding corn-soybean meal diets containing 3 CP levels (17, 19, and 21% CP) with supplementation on top of 0 or 2,400 U/kg multiprotease on chicken growth performance, total tract CP, and ileal AA digestibilities, and energy utilization. Ross 708 male chickens were placed in 42 cages and assigned to 6 treatments resulting from a 3 × 2 factorial arrangement. Three isocaloric basal diets were formulated to reduce CP, but all diets maintained digestible Lys:CP in 5.47% and the same ideal protein profile. Data were analyzed in a completely randomized design. On average, the multiprotease increased (P < 0.05) in vitro free AA release by 27.81% in most feedstuffs evaluated compared to the control. For broiler feed, 1,200 U/g multiprotease addition improved (P < 0.001) in vitro free AA release by 18.90%. This multiprotease showed interaction effects (P < 0.05) on chicken FCR, energy, and CP digestibility. As expected, BW at 24 d, BW gain, and FCR (8-24 d) worsened (P < 0.001) as dietary CP reduced from 21 to 17%, and multiprotease addition did not improve (P > 0.05) these parameters. BW gain decreased by 12.9% when N intake was reduced from 49.32 to 38.49 g/bird. Multiprotease supplementation improved (P < 0.01) AMEn by 71 kcal/kg, CP digestibility from 59.45 to 63.51%, ileal AA digestibility, and DM digestibility from 67.08 to 73.49%, but only in the 21% CP diet. No differences in ileal AA digestibility due to CP level (P > 0.05) were detected, except for Cys digestibility (P < 0.01). In conclusion, low CP diets reduced growth performance and improved N utilization but negatively affected energy utilization efficiency. Exogenous multiprotease supplementation improved AME, AMEn, protein, ileal AA, and DM digestibility in the 21% CP diet without significantly affecting growth performance.
Assuntos
Aminoácidos , Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Galinhas , Dieta , Proteínas Alimentares , Suplementos Nutricionais , Digestão , Metabolismo Energético , Animais , Galinhas/fisiologia , Galinhas/crescimento & desenvolvimento , Ração Animal/análise , Dieta/veterinária , Masculino , Aminoácidos/metabolismo , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , Metabolismo Energético/efeitos dos fármacos , Digestão/efeitos dos fármacos , Suplementos Nutricionais/análise , Proteínas Alimentares/metabolismo , Proteínas Alimentares/administração & dosagem , Distribuição Aleatória , Nutrientes/metabolismo , Peptídeo Hidrolases/metabolismo , Peptídeo Hidrolases/administração & dosagem , Relação Dose-Resposta a DrogaRESUMO
Performance and carcass traits of finishing pigs fed diets containing different levels of neutral detergent fiber (NDF) and acid detergent fiber (ADF) were evaluated through meta-analysis. The database was constructed using information from 24 papers, 113 treatments, and 2507 animals. Correlation and variance analyze were performed. The weight gain of the pigs showed a negative correlation (P 0.05) by the inclusion of ingredients with high NDF content. Likewise, the inclusion of ingredients with high ADF content did not alter (P > 0.05) feed intake and feed conversion ratio. However, the use of ingredients with a high ADF content reduced (P < 0.05) by 4% the weight gain of the pigs. The use of ingredients with high concentrations of NDF and ADF negatively affect the weight gain and feed conversion of finishing pigs; however, the ADF-related fraction has a positive relationship with the reduction of the backfat thickness.
O desempenho e as características de carcaça de suínos em terminação alimentados com dietas contendo diferentes níveis de fibra em detergente neutro (FDN) e fibra em detergente ácido (FDA) foram avaliados por meio de meta-análise. O banco de dados foi construído com informações de 24 artigos, 113 tratamentos e 2.507 animais. Análises de correlação e variância foram realizadas. O ganho de peso dos suínos apresentou correlação negativa (P 0,05) pela inclusão de ingredientes com alto teor de FDN. Da mesma forma, a inclusão de ingredientes com alto teor de FDA não alterou (P > 0,05) o consumo de ração e a conversão alimentar. Porém, o uso de ingredientes com alto teor de FDA reduziu (P < 0,05) em 4% o ganho de peso dos suínos. O uso de ingredientes com altas concentrações de FDN e FDA afetam negativamente o ganho de peso e conversão alimentar de suínos em terminação, porém fração relacionada a FDA tem relação positiva com a redução da espessura de toucinho.
Assuntos
Animais , Carne , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , Fibras na Dieta/efeitos adversos , SuínosRESUMO
Performance and carcass traits of finishing pigs fed diets containing different levels of neutral detergent fiber (NDF) and acid detergent fiber (ADF) were evaluated through meta-analysis. The database was constructed using information from 24 papers, 113 treatments, and 2507 animals. Correlation and variance analyze were performed. The weight gain of the pigs showed a negative correlation (P < 0.01) with the dietary NDF content and with NDF consumption. The feed conversion ratio showed a positive correlation (P < 0.01) with the inclusion of ADF in the test ingredient and with the consumption of NDF and ADF. The backfat thickness showed a negative correlation (P < 0.05) with the NDF content in the diets. The analysis of variance showed that the performance of finishing pigs was not influenced (P > 0.05) by the inclusion of ingredients with high NDF content. Likewise, the inclusion of ingredients with high ADF content did not alter (P > 0.05) feed intake and feed conversion ratio. However, the use of ingredients with a high ADF content reduced (P < 0.05) by 4% the weight gain of the pigs. The use of ingredients with high concentrations of NDF and ADF negatively affect the weight gain and feed conversion of finishing pigs; however, the ADF-related fraction has a positive relationship with the reduction of the backfat thickness.(AU)
O desempenho e as características de carcaça de suínos em terminação alimentados com dietas contendo diferentes níveis de fibra em detergente neutro (FDN) e fibra em detergente ácido (FDA) foram avaliados por meio de meta-análise. O banco de dados foi construído com informações de 24 artigos, 113 tratamentos e 2.507 animais. Análises de correlação e variância foram realizadas. O ganho de peso dos suínos apresentou correlação negativa (P < 0,01) com o teor de FDN da dieta e com o consumo de FDN. A taxa de conversão alimentar apresentou correlação positiva (P < 0,01) com a inclusão de FDA presente nos ingredientes testados e com o consumo de FDN e FDA. A espessura do toucinho apresentou correlação negativa (P < 0,05) com o teor de FDN das dietas. A análise de variância mostrou que o desempenho dos suínos em terminação não foi influenciado (P > 0,05) pela inclusão de ingredientes com alto teor de FDN. Da mesma forma, a inclusão de ingredientes com alto teor de FDA não alterou (P > 0,05) o consumo de ração e a conversão alimentar. Porém, o uso de ingredientes com alto teor de FDA reduziu (P < 0,05) em 4% o ganho de peso dos suínos. O uso de ingredientes com altas concentrações de FDN e FDA afetam negativamente o ganho de peso e conversão alimentar de suínos em terminação, porém fração relacionada a FDA tem relação positiva com a redução da espessura de toucinho.(AU)
Assuntos
Animais , Carne , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , Fibras na Dieta/efeitos adversos , SuínosRESUMO
BACKGROUND: Skeletal muscle is the most important organ for whole-body glucose homeostasis. However, it has been suggested that obesity-related inflammation could be involved in insulin resistance and diabetes mellitus type 2 (DM2) development due several mechanisms, among them, the reduced expression of the glucose transporter type 4 (GLUT-4). Gamma-oryzanol (γOz) is a compound present in the whole grain of rice that presents anti-inflammatory and antioxidant activities. The aim of this study was to verify if the effect antioxidant and anti-inflammatory of yOz attenuate insulin resistance in skeletal muscle of obese rats by increasing GLUT- 4 expression. METHODS: Male Wistar rats (±187 g) were initially randomly distributed into 2 experimental groups (control, n = 6, and high sugar-fat diet (HSF), n = 12) for 20 weeks. At week 20th of this study, once obesity and insulin resistance were detected in the HSF group, animals were divided to begin the treatment with γOz or continue receiving HSF for 10 more weeks. At the end it was analyzed nutritional, metabolic, inflammatory and oxidative stress parameters and GLUT-4 protein expression. RESULTS: The treatment improved insulin resistance, reduced inflammation, increased antioxidant response and GLUT-4 expression. CONCLUSION: It is possible to conclude that the antioxidant and anti-inflammatory activity of yOz attenuates insulin resistance by increasing GLUT-4 expression in skeletal muscle of obese animals.
Assuntos
Anti-Inflamatórios/farmacologia , Antioxidantes/farmacologia , Transportador de Glucose Tipo 4/metabolismo , Resistência à Insulina , Músculo Esquelético/patologia , Obesidade/patologia , Fenilpropionatos/farmacologia , Fenômenos Fisiológicos da Nutrição Animal/efeitos dos fármacos , Animais , Glicemia/metabolismo , Jejum/sangue , Teste de Tolerância a Glucose , Inflamação/patologia , Insulina/sangue , Peroxidação de Lipídeos/efeitos dos fármacos , Masculino , Músculo Esquelético/efeitos dos fármacos , Obesidade/sangue , Obesidade/fisiopatologia , Carbonilação Proteica/efeitos dos fármacos , Ratos WistarRESUMO
This study aimed to evaluate the effects of different traditional or alternative energy and protein sources, associated or not, on feeding behavior, ruminal kinetics, and post-ruminal flow of nutrients. Besides, it was assessed diets' effects on different sites (reticulum and omasum) of buffaloes. Four ruminally cannulated male Murrah buffaloes (average initial weight of 637 ± 66.37 kg) were randomly distributed in a 4 × 4 Latin square design. Treatments were arranged as 2 × 2 factorial arrangement. The first factor evaluated was the inclusion of energy sources (ground corn and crude glycerin), and the second factor was the inclusion of protein sources (soybean meal and cottonseed cake). Buffaloes fed cottonseed cake had a higher content of neutral detergent fiber (NDF) and potentially digestible detergent fiber (pdNDF) in the rumen environment than buffaloes fed soybean meal. There was a sampling site effect on rumen digestion rates of pdNDF, passage rates of indigestible neutral detergent fiber (iNDF), and pdNDF, and flow of iNDF. In this study, omasal collections were more representative. Total replacement of ground corn by crude glycerin promoted less NDF ruminal digestibility, and care should be taken to include this energy source. The cottonseed cake does not cause a difference in rumen dynamics and can totally replace soybean meal in feedlot buffaloes' diet.