RESUMO
Background: Subacute sclerosing panencephalitis (SSPE) is a disease of childhood and adolescence, but can affect adults. Rapidly progressive cognitive decline, seizures including myoclonic jerks, spasticity, ataxia, visual disturbances, and incontinence are typical manifestations. Case report: A 62-year-old woman who presented with rapidly progressive dementia and myoclonus was diagnosed with SSPE. There was resolution of the movement disorder with clonazepam and valproic acid treatment and some amelioration of cognitive decline after 3 months of therapy with interferon alfa and isoprinosine. Discussion: With the recent rise in measles cases worldwide, any increased incidence of SSPE would require vigilance for early interventions.
Assuntos
Demência/diagnóstico por imagem , Progressão da Doença , Mioclonia/diagnóstico por imagem , Panencefalite Esclerosante Subaguda/diagnóstico por imagem , Demência/complicações , Feminino , Humanos , Pessoa de Meia-Idade , Mioclonia/complicações , Panencefalite Esclerosante Subaguda/complicações , Fatores de TempoAssuntos
Meningomielocele/complicações , Meningomielocele/cirurgia , Mioclonia/etiologia , Doenças da Medula Espinal/diagnóstico por imagem , Doenças da Medula Espinal/etiologia , Vértebras Cervicais , Humanos , Lactente , Masculino , Meningomielocele/diagnóstico por imagem , Mioclonia/diagnóstico por imagem , Mioclonia/cirurgia , Doenças da Medula Espinal/cirurgia , Vértebras Torácicas , Derivação VentriculoperitonealRESUMO
A 70 years-old man was admitted at our hospital because of unstable angina pectoris. He had essential hypertension and right hemiplegia from a ischemic stroke two years before admission. On neurologic examination, it was found mental disorientation, unstable emotionality, right spastic hemiparesis with right Babinski sign, and segmental myoclonus affecting the superior lip and the palate (palatal nystagmus) on the right side. On the CT scan, a giant aneurysm of the basilar artery was detected. We conclude that the segmental myoclonus could be explained by ischemic lesions in the Guillain-Mollaret triangle.