RESUMO
La prevención incluye medidas destinadas no solo a prevenir la aparición de la enfermedad, sino también a detener su avance y atenuar las posibles consecuencias una vez diagnosticada. El modelo clásico de Leavell y Clark constituye una estrategia de prevención, que en ocasiones se usa en función de los niveles de atención médica y su complejidad; aspecto que trae confusión. En tal sentido, en el presente artículo se pretende reflexionar sobre los principales elementos a tener en cuenta en la prevención terciaria, que es la que se aplica en las unidades de cuidados intensivos, dadas las interrogantes que genera el tema.
Prevention includes measures not only dedicated to prevent the emergence of the disease, but also to stop its advance and attenuate the possible consequences once it is established. The classic pattern of Leavell and Clark constitutes a prevention strategy that is sometimes used associated with the medical care levels and its complexity; aspect that brings confusion. In such a sense, this work aims at reflecting on the main elements to take into account in the tertiary prevention that is implemented in the intensive care units, given the questions that the topic generates.
Assuntos
Prevenção de Doenças , Prevenção Terciária , Níveis de Atenção à Saúde , Unidades de Terapia Intensiva , Cuidados de EnfermagemRESUMO
OBJETIVO: Este artigo analisou o perfil epidemiológico e clínico dos pacientes atendidos em um serviço terciário de Dermatologia no município de Ponta Grossa-PR no período de 2016 a 2018. MÉTODOS: Trata-se de um estudo descritivo, exploratório, transversal e de abordagem quantitativa com dados coletados do prontuário médico. RESULTADOS: A maioria dos pacientes atendidos (I) era do sexo feminino; (II) com mais de 50 anos; (III) realizaram somente uma consulta, (IV) não foram submetidos a exames adicionais; e (V) apresentavam comorbidades, sobretudo, dermatológicas; o segmento corporal com maior número de lesões dermatológicas foi a cabeça; o grupo diagnóstico mais comum foi a afecção dos anexos cutâneos e o diagnóstico mais frequente foi a ceratose actínica. CONCLUSÃO: O estudo é fundamental para demonstrar quais são os pacientes e as doenças dermatológicas comumente encaminhadas para o serviço especializado, o que pode direcionar ações de prevenção primária, secundária e terciária.
OBJECTIVE: This article analyzed the epidemiological and clinical profile of patients treated at the outpatient Dermatology clinic, during 2016-2018, located in the municipality of Ponta Grossa-PR. METHODS: This is a descriptive exploratory, cross-sectional study with a quantitative approach, with data collected from the medical records. RESULTS: Most of the patients examinated: (I) were female; (II) over 50 years old; (III) attended to a single consultation; (IV) were not submitted to additional exams; and (V) had comorbidities, especially dermatological; the head was the most affected body segment; the most common diagnostic group was cutaneous annexes affections and the most frequent diagnosis was actinic keratosis. CONCLUSION: The study is fundamental to demonstrate who are the patients and which are the dermatological diseases commonly referred to the specialized service, which can guide primary, secondary and tertiary prevention actions.
OBJETIVO: Este artículo analizó el perfil epidemiológico y clínico de los pacientes atendidos en un servicio terciario de Dermatología en el municipio de Ponta Grossa-PR en el período de 2016 a 2018. MÉTODOS: Se trata de un estudio descriptivo, exploratorio y transversal con un enfoque cuantitativo con datos recogidos de las historias clínicas. RESULTADOS: La mayoría de los pacientes atendidos (I) eran mujeres; (II) tenían más de 50 años; (III) tenían una sola consulta, (IV) no se sometieron a exámenes adicionales; y (V) presentaban comorbilidades, principalmente, dermatológicas; el segmento corporal con mayor número de lesiones dermatológicas fue la cabeza; el grupo diagnóstico más común fue la afección de apéndices cutáneos y el diagnóstico más frecuente fue la queratosis actínica. CONCLUSIÓN: El estudio es fundamental para demostrar cuáles son los pacientes y las enfermedades dermatológicas que se derivan habitualmente al servicio especializado, lo que puede dirigir las acciones de prevención primaria, secundaria y terciaria.
Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Perfil de Saúde , Epidemiologia , Dermatologia , Prevenção Terciária , Dermatopatias/etiologia , Prontuários Médicos/estatística & dados numéricos , Estudos Transversais/métodos , Dermatite/etiologia , Eczema/etiologiaRESUMO
Toxoplasmosis acquired during pregnancy is one that can lead to death or malformations of the foetus, and it is a complex disease to diagnose. The objective of the study was to evaluate the Surveillance Program of Gestational and Congenital Toxoplasmosis. To assess primary prevention, 424 pregnant women were interviewed regarding their knowledge of prevention measures in 2019. Secondary prevention measures were assessed, and the results of anti-Toxoplasma gondii serological tests were collected from pregnant women, from 2015 to 2018. In tertiary prevention measures, babies of mothers with a recent suspicion of T. gondii infection were screened to verify forwarding to the reference service. As a result, 45.5% (192/424) reported that they had received guidance from health professionals; 35.4% (68/192) changed their risk habits. The variables of schooling and age, having received prior guidance from health professionals and feline possession, proved to be significant when associated with the notions of preventive measures. 90.2% (17,423/19,319) of pregnant women had undergone serological tests to detect anti-T. gondii antibodies, but there was an excess in requests for tests and medication and only 40.6% (26/64) of the children were referred to the reference hospital. The Program presents positive results about the performance of serological screening in prenatal care; however, the dissemination of knowledge as for the prevention of toxoplasmosis and the request for tests need to be improved.
Assuntos
Doenças do Gato , Toxoplasma , Toxoplasmose Congênita , Toxoplasmose , Animais , Anticorpos Antiprotozoários , Gatos , Feminino , Humanos , Imunoglobulina M , Gravidez , Cuidado Pré-Natal , Estudos Soroepidemiológicos , Prevenção Terciária , Toxoplasmose/epidemiologia , Toxoplasmose Congênita/diagnóstico , Toxoplasmose Congênita/epidemiologia , Toxoplasmose Congênita/prevenção & controleRESUMO
PURPOSE: There is growing evidence of an association between physical activity and a reduced risk of cancer and cancer recurrence. The aim of this study was to assess the effects of exercise-conditioned human serum (HS) effects on the proliferative and tumorigenic potential of triple-negative breast cancer (TNBC) and prostate cancer (PC) cells. Moreover, modulated mechanisms and several physiological factors that can predict exercise effects were investigated. METHODS: Thirty healthy sedentary subjects were recruited for the study. The subjects performed two high-intensity endurance cycling (HIEC) sessions before and after a nine-week period of high-intensity interval training (HIIT). Cell tumorigenic capacity affected by HS collected before (t0), immediately after (t1), 4 h (t2), and 24 h (t3) after the HIEC sessions was evaluated by in vitro three-dimensional colony formation. The modulation of molecular pathways was analyzed by western blotting and qPCR in TNBC and PC cells, and in TNBC xenografts in exercised mice. RESULTS: All of the HIEC-conditioned HS (t1, t2, and t3) markedly impacted the proliferative and the microtumor-forming capacity of both TNBC and PC cell lines, while the HS collected from the subjects at rest did not. Modulation of the Hippo and Wnt/ß-catenin pathways by HIEC-conditioned HS before and after the period of HIIT was shown. Multiple linear regression analysis showed relationships between the effects of HIEC-conditioned HS in PC cells, lactate threshold and VO2max. CONCLUSIONS: These results highlight the potential of HIEC bouts in tumor progression control and the importance of optimizing an approach to identify physiological predictors of the effects of acute exercise in tertiary cancer prevention.
Assuntos
Ciclismo/fisiologia , Proliferação de Células/fisiologia , Treinamento Intervalado de Alta Intensidade , Neoplasias da Próstata/patologia , Neoplasias de Mama Triplo Negativas/patologia , Animais , Linhagem Celular Tumoral , Meios de Cultivo Condicionados , Progressão da Doença , Feminino , Glicogênio Sintase Quinase 3 beta/metabolismo , Via de Sinalização Hippo , Humanos , Masculino , Camundongos , Proteína Quinase 1 Ativada por Mitógeno/metabolismo , Proteína Quinase 3 Ativada por Mitógeno/metabolismo , Fosforilação , Neoplasias da Próstata/prevenção & controle , Proteínas Serina-Treonina Quinases/metabolismo , Distribuição Aleatória , Análise de Regressão , Comportamento Sedentário , Prevenção Terciária , Fatores de Tempo , Neoplasias de Mama Triplo Negativas/prevenção & controle , Ensaio Tumoral de Célula-Tronco/métodos , Via de Sinalização Wnt , Adulto JovemRESUMO
Resumen En diciembre de 2019, se informaron casos de neumonía potencialmente mortal en Wuhan, provincia de Hubei, China (COVID-19). Esta enfermedad se ha extendido rápidamente por todo el mundo con miles de casos confirmados y muertes, transformándose en pandemia y desafiado los sistemas de salud pública. No existe aún vacuna ni tratamiento científicamente probado, sin embargo, se ha identificado los comportamientos exactos que pueden evitar el contagio y propagación. El presente artículo sistematiza información disponible inicial sobre psicología y COVID-19. Se discute que gran parte del problema de la enfermedad se puede evitar cambiando los comportamientos de las personas y que la psicología puede ayudar a explicar, prevenir e intervenir para su solución. La psicología cuenta con evidencia científica disponible que explica todos estos fenómenos, evidencia que debe ser puesta en relieve por los mismos actores de las disciplinas a disposición de otras áreas del conocimiento y sobre todo para los tomadores de decisión.
Abstract In December 2019, highly lethal cases of pneumonia were reported in Wuhan, Hubei Province, China (COVID-19). This disease has spread rapidly around the world with thousands of confirmed cases and deaths, becoming a pandemic and challenging public health systems. There is no vaccine or scientifically proven treatment yet, but the exact behaviours that can prevent transmission and spread have been identified. This article systematizes initial available information on psychology and COVID-19. It is discussed that much of the problem of the disease can be avoided by changing people's behaviors and that psychology can help explain, prevent and intervene to solve it. Psychology has scientific evidence available that explains all these phenomena, evidence that should be highlighted by the same actors in the disciplines available to other areas of knowledge and especially for decision makers.
Assuntos
Humanos , Pneumonia Viral/prevenção & controle , Pneumonia Viral/psicologia , Psicologia , Infecções por Coronavirus/prevenção & controle , Infecções por Coronavirus/psicologia , Prevenção Primária , Medicina do Comportamento , Saúde Pública , Pessoal de Saúde/psicologia , Intervenção em Crise , Prevenção Secundária , Prevenção Terciária , PandemiasRESUMO
Resumen El presente artículo expone el resultado de una evaluación cualitativa sobre las acciones que los servicios públicos de salud desarrollan para la prevención de embarazos subsiguientes en adolescentes, en un estado en el centro-norte de México. El objetivo fue documentar los obstáculos percibidos para prevenir embarazos subsiguientes en madres adolescentes. La información se obtuvo entre 2016-2018, mediante entrevistas individuales en los domicilios de jóvenes usuarias de servicios públicos de salud. El análisis de la información se hizo a partir de la propuesta de Strauss y Corbin para teoría fundamentada. Las experiencias compartidas por las jóvenes madres fueron analizadas y clasificadas en dos categorías, obstáculos asociados a: (1) competencias profesionales, y (2) a imaginarios morales. Se concluye que las limitaciones más importantes tienen que ver con el hecho de que la estrategia de servicios amigables para adolescentes deja de implementarse en aquellas que han sido madres, sin considerar el impacto biológico y psicosocial que tienen los embarazos subsiguientes en la adolescencia y la necesidad de postergar la reproducción hasta la edad adulta.
Abstract This article presents the result of a qualitative evaluation of the actions that the public health services develop for the prevention of subsequent adolescent pregnancies in a state in north-central Mexico. The objective was to document the perceived obstacles to preventing subsequent teenage pregnancies in teenage mothers. The information was obtained in the period 2016-2018, by individual interviews in the homes of young users of public health services. The analysis of the information was based on Strauss and Corbin's proposal for the grounded theory. The experiences shared by the young mothers were analyzed and classified into two categories, obstacles associated with: (1) professional competences, and (2) with moral imagery. It is concluded that the most important limitations are related to the fact that the strategy of adolescent friendly services is no longer implemented in those who have been mothers, without considering the biological and psychosocial impact that subsequent pregnancies have in adolescence and the need to delay reproduction until adulthood.
Assuntos
Humanos , Feminino , Gravidez , Adolescente , Gravidez na Adolescência/prevenção & controle , Pesquisa Qualitativa , Prevenção Terciária , Serviços Públicos de SaúdeRESUMO
Hemolytic uremic syndrome (HUS) associated with intestinal infection by Shiga toxin-producing bacteria, which mainly affects children, can cause severe acute morbidity, chronic sequelae in seve ral organs, and premature death in some of them. Given its zoonotic nature, adequate measures of agricultural management and proper hygiene of what we consume are essential to prevent infection. Once the HUS is triggered, medical management is currently mainly supportive. In recent years, va rious therapeutic strategies have been developed to prevent this disease from occurring or, at least, to mitigate its morbidity and mortality consequences. This article describes specific actions at different levels of prevention of this pathology.
Assuntos
Síndrome Hemolítico-Urêmica/prevenção & controle , Toxinas Shiga/efeitos adversos , Síndrome Hemolítico-Urêmica/diagnóstico , Síndrome Hemolítico-Urêmica/etiologia , Síndrome Hemolítico-Urêmica/terapia , Humanos , Prevenção Primária/métodos , Prevenção Secundária/métodos , Prevenção Terciária/métodosRESUMO
Resumen: El síndrome hemolítico urémico (SHU) asociado a infección intestinal por bacterias productoras de Shigatoxina, que afecta principalmente a población infantil, puede causar morbilidad aguda grave, secuelas crónicas en varios órganos, y la muerte prematura en algunos de ellos. Dado su carácter zoonótico, adecuadas medidas de manejo agropecuario y correcta higiene de lo que consumimos es indispensable a la hora de prevenir la infección. Actualmente, una vez gatillado el SHU el manejo es médico y, principalmente, de soporte. En los últimos años diversas estrategias terapéuticas se han ido desarrollando para evitar que esta enfermedad ocurra, o, al menos, que pueda ser atenuada en sus consecuencias de morbi-mortalidad. El presente artículo describe acciones específicas a diferentes niveles de prevención de esta patología.
Abstract Hemolytic uremic syndrome (HUS) associated with intestinal infection by Shiga toxin-producing bacteria, which mainly affects children, can cause severe acute morbidity, chronic sequelae in seve ral organs, and premature death in some of them. Given its zoonotic nature, adequate measures of agricultural management and proper hygiene of what we consume are essential to prevent infection. Once the HUS is triggered, medical management is currently mainly supportive. In recent years, va rious therapeutic strategies have been developed to prevent this disease from occurring or, at least, to mitigate its morbidity and mortality consequences. This article describes specific actions at different levels of prevention of this pathology.
Assuntos
Humanos , Toxinas Shiga/efeitos adversos , Síndrome Hemolítico-Urêmica/prevenção & controle , Prevenção Primária/métodos , Prevenção Secundária/métodos , Prevenção Terciária/métodos , Síndrome Hemolítico-Urêmica/diagnóstico , Síndrome Hemolítico-Urêmica/etiologia , Síndrome Hemolítico-Urêmica/terapiaRESUMO
Introducción: Las enfermedades reumáticas, debido a su evolución natural, provocan afectaciones a la calidad de vida de las personas afectadas por eso es de vital importancia el diagnóstico temprano, el tratamiento oportuno y la prevención. El conocimiento de los adelantos contemporáneos en la atención de salud es una herramienta que ayuda a tomar decisiones clínicas en la práctica diaria, aunque la decisión final sobre el diagnóstico y el tratamiento de un paciente determinado dependerá de las características particulares de cada uno. Objetivo: Discutir algunos avances en la atención de salud a los pacientes con en enfermedades reumáticas. Desarrollo: Debido a que en la práctica clínica se encuentran con frecuencia resultados discordantes, la actualización de temas como este permite socializar los resultados obtenidos con profesionales del gremio, mostrar las estrategias más efectivas o los mejores métodos para el diagnóstico precoz, tratamiento y cuidado de estas enfermedades sobre la base de experiencias asistenciales e investigativas en varias regiones del mundo o en contextos diferentes. Conclusiones: Para controlar mejor las enfermedades reumáticas se necesita una estrategia organizativa en el marco de la cual se aprovechen las fortalezas de la prevención primaria, secundaria y terciaria y que los profesionales, de acuerdo con sus conocimientos y competencias, lleven a cabo acciones que prevengan las graves complicaciones de estas enfermedades. En varios estudios clínicos y ensayos terapéuticos se trabaja con novedosos fármacos biológicos, donde se evalúa su efectividad, se identifican los efectos adversos y se valora la relación riesgo-beneficio(AU)
Rheumatic diseases, due to their natural evolution, bring with them effects on the quality of life of the people carrying this conditions, which is why their early diagnosis, timely treatment and prevention are of vital importance. The knowledge of contemporary advances in health care is a tool to help when making clinical decisions in daily practice, although the final decision on the diagnostic or therapeutic approach of a specific patient will depend on the characteristics of the same. Objective: to discuss some advances in health care in rheumatoid diseases. Development: due to the fact that in clinical practice discordant results are frequently found, the updating of topics such as these allows to socialize the results obtained with professionals of the guild, to show the most effective strategies or the best methods for the early diagnosis, treatment and management of these diseases, on the basis of assistance and research experiences in various regions of the world or in different contexts. Conclusions: for a better control of rheumatic diseases requires a strategy of articulation where the strengths of primary, secondary and tertiary prevention are exploited, where the professionals in accordance with their competence execute actions that prevent the serious complications of these diseases and where properly treat infectious processes in particular, those produced by Streptococcus A, among others. Results of several clinical trials and therapeutic trials work with novel biological drugs, assessing their effectiveness, identifying adverse effects, assessing the risk-benefit ratio and the convenience of these forming part of the treatment scheme against various targets(AU)
Assuntos
Humanos , Masculino , Feminino , Prevenção Primária , Doenças Reumáticas/prevenção & controle , Competência Mental , Prevenção Terciária , Diagnóstico PrecoceRESUMO
Resumen Estudio descriptivo que permitió caracterizar los programas y las actividades de promoción de la salud y prevención de la enfermedad en cuatro instituciones de salud de alta complejidad de Medellín. Por medio de un estudio descriptivo de serie de casos, se aplicaron dos instrumentos semiestructurados tipo encuesta donde se recolectó información sobre: estructura y funcionamiento, enfoque, públicos beneficiarios, metodologías y equipos de trabajo. Se encontró que las cuatro instituciones desarrollan actividades de este tipo, con un enfoque hacia la prevención terciaria congruente con su nivel de complejidad; están orientadas esencialmente al paciente y a las familias, y, a veces, a la comunidad; los empleados también se benefician desde salud ocupacional; son desarrolladas por profesionales de diferentes disciplinas; su funcionamiento depende generalmente de las direcciones científicas; no se identifica un área en particular que las gestione articuladamente. Se considera importante que las instituciones se declaren a favor de modelos de atención en salud integrales donde se trabaje de manera articulada las actividades de promoción y prevención con la atención clínica.
Abstract This is a descriptive study that allowed for the characterization of the health promotion and disease prevention programs and activities in four high-complexity health institutions in Medellín. By means of a descriptive study of a series of cases, two semi-structured survey instruments were applied through which information was collected on: structure and functioning, approach, beneficiary communities, methodologies, and work teams. We found that all four institutions develop activities of this type, with a focus on tertiary prevention consistent with their level of complexity; they are essentially oriented to the patient and their families, and, sometimes, to the community; employees also benefit from occupational health; the activities are developed by professionals from different disciplines; their operation depends in general terms on scientific management; and no particular area was identified to manage the activities articulately. We considered important that the institutions manifest to be in favor of integral health care models where the promotion and prevention activities are coordinated with clinical care.
Resumo Estudo descritivo que permitiu caracterizar os programas e atividades de promoção da saúde e prevenção de doença em quatro instituições de saúde de alta complexidade de Medellín. Por meio de estudo descritivo de série de casos, aplicaram-se dois instrumentos semiestruturados tipo inquérito onde foi coletada informação sobre: estrutura e funcionamento, enfoque, públicos beneficiários, metodologias e equipes de trabalho. Verificou-se que as quatro instituições desenvolvem atividades deste tipo, com enfoque para a prevenção terciária congruente com o seu nível de complexidade; são orientadas essencialmente ao paciente e as famílias, e, às vezes, à comunidade; os empregados também são beneficiados desde saúde ocupacional; são desenvolvidas por profissionais de diferentes disciplinas; o seu funcionamento depende geralmente das direções científicas; não se identifica uma área em particular que as gere articuladamente. Considera-se importante as instituições se declararem em favor de modelos de atenção em saúde integrais onde se trabalharem de maneira articulada as atividades de promoção e prevenção com a atenção clínica.