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J Neurovirol ; 23(6): 932-934, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-29147884

RESUMO

Zika virus (ZIKV) is an emerging flavivirus which has been linked to a number of neurologic manifestations such as Guillain-Barré syndrome (GBS), transverse myelitis, and meningo-encephalitis. Ophthalmologic manifestations are increasingly being reported; however, ocular dyskinesias have not been described in this context to date. Herein, we report a case of a 22-year-old female who presented with ocular flutter and associated Guillain-Barré syndrome following acute ZIKV infection. We speculate that although such symptoms may have originated from a direct viral insult, a post-infectious autoimmune mechanism may not be excluded. Physicians should include ZIKV as well as other flaviviruses in their diagnostic workup for all patients with ocular flutter/opsoclonus, after excluding other non-infectious causes of central nervous system pathology. To the best of our knowledge, this is the first report on the association of ocular flutter, GBS, and ZIKV infection.


Assuntos
Ataxia/diagnóstico , Síndrome de Guillain-Barré/diagnóstico , Transtornos da Motilidade Ocular/diagnóstico , Infecção por Zika virus/diagnóstico , Aciclovir/uso terapêutico , Anticorpos Antivirais/sangue , Antivirais/uso terapêutico , Ataxia/tratamento farmacológico , Ataxia/fisiopatologia , Ataxia/virologia , Feminino , Síndrome de Guillain-Barré/tratamento farmacológico , Síndrome de Guillain-Barré/fisiopatologia , Síndrome de Guillain-Barré/virologia , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Transtornos da Motilidade Ocular/tratamento farmacológico , Transtornos da Motilidade Ocular/fisiopatologia , Transtornos da Motilidade Ocular/virologia , Adulto Jovem , Zika virus/imunologia , Infecção por Zika virus/tratamento farmacológico , Infecção por Zika virus/fisiopatologia , Infecção por Zika virus/virologia
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