RESUMO
Glomus tumor is a rather common tumor of the hand, which presents with a classic triad of symptoms of high temperature, sensitivity and pain, and localized tenderness. Most glomus tumors are located in the digits, especially in subungueal areas. However, extradigital tumors are less frequent, and little is known about their clinical and histopathological features. Two cases of extradigital symplastic glomus tumor are presented. An active clinical and pathological awareness to avoid misdiagnosis or delayed diagnosis of this uncommon lesion is highlighted.
Assuntos
Tumor Glômico/patologia , Mãos , Neoplasias Cutâneas/patologia , Adulto , Idoso , Feminino , Tumor Glômico/química , Tumor Glômico/cirurgia , Humanos , Neoplasias Cutâneas/química , Neoplasias Cutâneas/cirurgiaRESUMO
The gross and microscopical features of a glomus tumour in the digit of a 9-year-old dog are described. The tumour consisted of a red nodule near the nail of the third digit of the right forelimb and appeared painful. The tumour cells, which had round to oval hyperchromatic nuclei and scant cytoplasm, were arranged in sheets around blood vessels, or in nests or duct-like structures. This pattern has not been described previously in canine glomus tumours. Mitotic figures were seen only occasionally. Tumour cells were strongly immunolabelled for vimentin and some expressed smooth-muscle actin and desmin. They were negative for cytokeratins, neuron-specific enolase and CD34. Silver impregnation (reticulin method) stained the reticulum around blood vessels, nests of tumour cells and duct-like structures, and a delicate reticulum was seen around each tumour cell. The morphological, immunohistochemical and histochemical patterns helped in the diagnosis of this glomus tumour.
Assuntos
Doenças do Cão/patologia , Doenças do Pé/veterinária , Tumor Glômico/veterinária , Neoplasias Cutâneas/veterinária , Animais , Biomarcadores Tumorais/análise , Doenças do Cão/cirurgia , Cães , Feminino , Doenças do Pé/patologia , Doenças do Pé/cirurgia , Membro Anterior/patologia , Membro Anterior/cirurgia , Tumor Glômico/química , Tumor Glômico/patologia , Tumor Glômico/cirurgia , Técnicas Imunoenzimáticas/veterinária , Coloração pela Prata/veterinária , Neoplasias Cutâneas/química , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia , Resultado do Tratamento , Vimentina/análiseRESUMO
An 8-year-old girl was seen in our outpatient clinic with a history of an angiomatous plaque on the chest since birth. She had complained of pain at the site of the lesion for 1 month. Histopathologic examination and immunohistochemical analysis led to the diagnosis of glomangioma, a rare congenital plaquelike glomus tumor. We review the literature and discuss the clinical presentation and evolution of this rare entity.
Assuntos
Tumor Glômico/congênito , Neoplasias Cutâneas/congênito , Actinas/análise , Criança , Feminino , Tumor Glômico/química , Tumor Glômico/patologia , Humanos , Imuno-Histoquímica , Pele/patologia , Neoplasias Cutâneas/química , Neoplasias Cutâneas/patologia , Tórax , Vimentina/análiseRESUMO
Se describe un caso de tumor glómico solitario, el cual microscópicamente podría encuadrarse en la rara variante de glomangiomioma y que muestra un aspecto clínico atípico, relación que se pretende resaltar.