Failure to induce delayed-type hipersensivity to Mycobacterium leprae in long-term treated lepromatous leprosy patients
s.l; s.n; jun. 1981. 5 p. tab, graf.
Non-conventional
em En
| SES-SP, HANSEN, HANSENIASE, SESSP-ILSLACERVO, SES-SP
| ID: biblio-1240498
Biblioteca responsável:
BR191.1
Localização: [{"text": "BR191.1", "_a": "00542/s"}]
ABSTRACT
Lepromatous leprosy (LL) patients whose bacillary load has decreased to almost undetectable levels by long-term chemotherapy failed to develop delayed-type hypersensitivity (DTH) to Mycobacterium leprae antigen following immunization with killed armadillo-derived m. leprae. When these LL patients were immunized with killed M. leprae in a mixture with live BCG, only DTH to purified protein derivative (PPD) was induced. These results are further evidence that immunological unresponsiveness to the leprosy antigen of patients with lepromatous leprosy is antigen-specific and non-reversible.
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Coleções:
06-national
/
BR
Base de dados:
HANSEN
/
HANSENIASE
/
SES-SP
/
SESSP-ILSLACERVO
Assunto principal:
Testes Cutâneos
/
Imunização
/
Hipersensibilidade Tardia
/
Hanseníase
/
Mycobacterium bovis
/
Mycobacterium leprae
/
Antígenos de Bactérias
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Non-conventional