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Delayed diagnosis and increased mortality risk: Assessing the effects of the COVID-19 pandemic on breast cancer recurrence
Mühlmann, Lindson; Pimentel, Franklin Fernandes; Tiezzi, Daniel Guimarães; Carrara, Hélio Humberto Angotti; Andrade, Jurandyr Moreira de; Reis, Francisco José Candido dos.
Afiliação
  • Mühlmann, Lindson; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Gynecology and Obstetrics. Ribeirão Preto. BR
  • Pimentel, Franklin Fernandes; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Gynecology and Obstetrics. Ribeirão Preto. BR
  • Tiezzi, Daniel Guimarães; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Gynecology and Obstetrics. Ribeirão Preto. BR
  • Carrara, Hélio Humberto Angotti; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Gynecology and Obstetrics. Ribeirão Preto. BR
  • Andrade, Jurandyr Moreira de; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Gynecology and Obstetrics. Ribeirão Preto. BR
  • Reis, Francisco José Candido dos; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Gynecology and Obstetrics. Ribeirão Preto. BR
Clinics ; 79: 100340, 2024. tab, graf
Article em En | LILACS-Express | LILACS | ID: biblio-1557593
Biblioteca responsável: BR1.1
ABSTRACT
Abstract Objectives The COVID-19 pandemic has had a significant global impact since its declaration in March 2020. The COVID-19 pandemic has disproportionately impacted cancer patients, particularly those with breast cancer. This study aims to analyze the effects of the pandemic on women diagnosed with breast cancer recurrence. Methods A cohort study was conducted at a tertiary public hospital in São Paulo State, Brazil. Data were collected from electronic records. Patients diagnosed with breast cancer and experiencing recurrence between January 2011 and March 2022 were included. Survival analysis was performed using the Kaplan-Meier estimator and Cox regression. Results The study included 187 patients, 45 in the pandemic group (recurrence after March 23, 2020) and 142 in the pre-pandemic group. Distant recurrences were more frequent in both groups (pre-pandemic 62.7 %, pandemic 75.5 %). Compared to the pre-pandemic group (1.8 years), the pandemic group experienced a longer mean time to recurrence detection (2.9 years) and significantly decreased median survival (9 months vs. 22 months). The Cox regression analysis confirmed an increased risk of death for women diagnosed with breast cancer recurrence during the pandemic period (HR = 1.92, 95 % CI 1.19‒3.12). Conclusion The present study is among the first to investigate the pandemic's specific effects on breast cancer recurrence, revealing concerning delays in detection and a decrease in survival rates. Prompt diagnosis, timely treatment initiation, and comprehensive support are crucial during public health crises. These findings urge healthcare systems to prioritize tailored care for breast cancer patients during pandemics.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil