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Characteristics of adolescents aged 15-19 years living with vertically and horizontally acquired HIV in Nampula, Mozambique
Teasdale, Chloe A; Brittain, Kirsty; Zerbe, Allison; Mellins, Claude Ann; Falcao, Joana; Couto, Aleny; De Gusmao, Eduarda Pimentel; Vitale, Mirriah; Kapogiannis, Bill; Simione, Teresa Beatriz; Myer, Landon; Mantell, Joanne; Desmond, Christopher; Abrams, Elaine J.
Afiliação
  • Teasdale, Chloe A; Department of epidemiology and biostatistics, cuny graduate school of public health & health policy. Icap at columbia university, mailman school of public health. Department of epidemiology, mailman school of public health, columbia university. New York. US
  • Brittain, Kirsty; Division of epidemiology & biostatistics, school of public health & family medicine, university of cape town. Centre for infectious disease epidemiology & research, school of public health & family medicine, university of cape town. Cape town. ZA
  • Zerbe, Allison; Icap at columbia university, mailman school of public health. New York. US
  • Mellins, Claude Ann; Department of psychiatry, hiv center for clinical and behavioral studies, new york state psychiatric institute and columbia university irving medical center. New York. US
  • Falcao, Joana; Icap at columbia university, mailman school of public health. New York. US
  • Couto, Aleny; National sti, hiv/aids control program. Maputo. MZ
  • De Gusmao, Eduarda Pimentel; Icap at columbia university, mailman school of public health. New York. US
  • Vitale, Mirriah; Icap at columbia university, mailman school of public health. New York. US
  • Kapogiannis, Bill; Eunice kennedy shriver national institute of child health and human development. Bethesda. US
  • Simione, Teresa Beatriz; National sti, hiv/aids control program. Maputo. MZ
  • Myer, Landon; Division of epidemiology & biostatistics, school of public health & family medicine, university of cape town. Centre for infectious disease epidemiology & research, school of public health & family medicine, university of cape town. Cape town. ZA
  • Mantell, Joanne; Department of psychiatry, hiv center for clinical and behavioral studies, new york state psychiatric institute and columbia university irving medical center. New York. US
  • Desmond, Christopher; Centre for rural health, university of kwazulu natal. Durban. ZA
  • Abrams, Elaine J; Icap at columbia university, mailman school of public health. Department of epidemiology, mailman school of public health, columbia university. Department of pediatrics, vagelos college of physicians and surgeons, columbia university. New York. US
PLoS One ; 16(4): 1-24, 2021. graf
Article em En | SES-SP, RSDM | ID: biblio-1561857
Biblioteca responsável: MZ1.1
ABSTRACT

Background:

Adolescents living with HIV (ALHIV) 15-19 years of age are a growing proportion of all people living with HIV globally and the population includes adolescents with vertically acquired HIV (AVH) and behaviorally acquired HIV (ABH).

Methods:

We conducted a survey to measure sociodemographic characteristics, educational status, health history, and antiretroviral therapy (ART) adherence among a convenience sample of ALHIV at three government health facilities in 2019 in Nampula, Mozambique. ALHIV 15-19 years on ART, including females attending antenatal care, were eligible. Routine HIV care data were extracted from medical charts. Classification of ALHIV by mode of transmission was based on medical charts and survey data. ALHIV who initiated ART <15 years or reported no sex were considered AVH; all others ABH. Frequencies were compared by sex, and within sex, by mode of transmission (AVH vs. ABH) using Chi-square, Fishers exact tests and Wilcoxon rank-sum tests.

Results:

Among 208 ALHIV, 143 (69%) were female and median age was 18 years [interquartile range (IQR) 16-19]. Just over half of ALHIV (53%) were in or had completed secondary or higher levels of education; the most common reason for not being in school reported by 36% of females was pregnancy or having a child. Of all ALHIV, 122 (59%) had VL data, 62% of whom were <1000 copies/mL. Almost half (46%) of ALHIV reported missing ARVs ≥ 1 day in the past month (62% of males vs. 39% of females; p = 0.003). Just over half (58%) of ALHIV in relationships had disclosed their HIV status 13% of males vs. 69% of females (p<0.001). Among sexually active males, 61% reported using a condom at last sex compared to 26% of females (p<0.001). Among female ALHIV, 50 (35%) were AVH and 93 (65%) were ABH, 67% of whom were not in school compared to 16% of ABH, (p<0.001).

Discussion:

Data from our study underscore the high level of deprivation among ALHIV enrolled in HIV care in Mozambique, as well as important disparities by sex and mode of transmission. These data can inform the development of effective interventions for this complex and important population.
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Texto completo: 1 Coleções: 06-national / BR Base de dados: RSDM / SES-SP Assunto principal: Infecções por HIV Limite: Adolescent / Female / Humans / Male País/Região como assunto: Africa Idioma: En Revista: PLoS One Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 06-national / BR Base de dados: RSDM / SES-SP Assunto principal: Infecções por HIV Limite: Adolescent / Female / Humans / Male País/Região como assunto: Africa Idioma: En Revista: PLoS One Ano de publicação: 2021 Tipo de documento: Article