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Agreement between frozen section and histopathology to detect malignancy in adnexal masses according to size and morphology by ultrasound
Amaral, Clarissa de Andrade; Pedrão, Priscila Grecca; Godoy, Luani Rezende; Guimarães, Yasmin Medeiros; Macedo, Cassia Arantes Petroni; Appel, Marcia; Accorsi, Guilherme Spagna; Zanon, Jeferson Rodrigo; Reis, Ricardo dos.
Afiliação
  • Amaral, Clarissa de Andrade; Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre. Porto Alegre. BR
  • Pedrão, Priscila Grecca; Hospital de Amor. Barretos. BR
  • Godoy, Luani Rezende; Hospital de Amor. Barretos. BR
  • Guimarães, Yasmin Medeiros; Hospital de Amor. Barretos. BR
  • Macedo, Cassia Arantes Petroni; Faculdade de Ciências da Saúde de Barretos Dr. Paulo Prata. Barretos. BR
  • Appel, Marcia; Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre. Porto Alegre. BR
  • Accorsi, Guilherme Spagna; Faculdade de Medicina de Catanduva. Catanduva. BR
  • Zanon, Jeferson Rodrigo; Hospital de Amor. Barretos. BR
  • Reis, Ricardo dos; Hospital de Amor. Barretos. BR
Rev. bras. ginecol. obstet ; 46: e, 2024. tab
Article em En | LILACS-Express | LILACS | ID: biblio-1569732
Biblioteca responsável: BR1.1
ABSTRACT
Abstract Objective Management of suspect adnexal masses involves surgery to define the best treatment. Diagnostic choices include a two-stage procedure for histopathology examination (HPE) or intraoperative histological analysis - intraoperative frozen section (IFS) and formalin-fixed and paraffin-soaked tissues (FFPE). Preoperative assessment with ultrasound may also be useful to predict malignancy. We aimed at determining the accuracy of IFS to evaluate adnexal masses stratified by size and morphology having HPE as the diagnostic gold standard. Methods A retrospective chart review of 302 patients undergoing IFS of adnexal masses at Hospital de Clínicas de Porto Alegre, between January2005 and September2011 was performed. Data were collected regarding sonographic size (≤10cm or >10cm), characteristics of the lesion, and diagnosis established in IFS and HPE. Eight groups were studied unilocular lesions; septated/cystic lesions; heterogeneous (solid/cystic) lesions; and solid lesions, divided in two main groups according to the size of lesion, ≤10cm or >10cm. Kappa agreement between IFS and HPE was calculated for each group. Results Overall agreement between IFS and HPE was 96.1% for benign tumors, 96.1% for malignant tumors, and 73.3% for borderline tumors. Considering the combination of tumor size and morphology, 100% agreement between IFS and HPE was recorded for unilocular and septated tumors ≤10cm and for solid tumors. Conclusion Stratification of adnexal masses according to size and morphology is a good method for preoperative assessment. We should wait for final HPE for staging decision, regardless of IFS results, in heterogeneous adnexal tumors of any size, solid tumors ≤10cm, and all non-solid tumors >10cm.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. bras. ginecol. obstet Assunto da revista: GINECOLOGIA / OBSTETRICIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. bras. ginecol. obstet Assunto da revista: GINECOLOGIA / OBSTETRICIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil