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Metastatic Lymphoepithelioma-like Hepatocellular Carcinoma: a Potential Diagnostic Pitfall and Demonstration of Pd-l1 Expression
Putra, Juan; Anderson, Todd A; Roayaie, Sasan; Maeda, Miho; Thung, Swan N.
Afiliação
  • Putra, Juan; Icahn School of Medicine at Mount Sinai. Department of Pathology. New York. US
  • Anderson, Todd A; Icahn School of Medicine at Mount Sinai. Department of Pathology. New York. US
  • Roayaie, Sasan; Icahn School of Medicine at Mount Sinai. Department of Pathology. New York. US
  • Maeda, Miho; Icahn School of Medicine at Mount Sinai. Department of Pathology. New York. US
  • Thung, Swan N; Icahn School of Medicine at Mount Sinai. Department of Pathology. New York. US
Ann. hepatol ; 16(1): 157-159, Jan.-Feb. 2017. graf
Article em En | LILACS | ID: biblio-838098
Biblioteca responsável: BR1.1
ABSTRACT
Abstract Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) is a rare primary hepatic neoplasm with female predominance and relatively good prognosis. We report a 73-year-old female with chronic hepatitis B who developed metastatic lesions 5 years after underwent resection for LEL-HCC. The metastatic lesions showed a spectrum of morphologic findings, which could be mistaken for other entities such as lymphoma, particularly in lesions with single-cell infiltrative pattern and abundant tumor-infiltrating lymphocytes. Immunohistochemical study to confirm the origin of the neoplastic cells is important to make the diagnosis. We also highlighted the clinicopathologic correlation and potential therapeutic implication of programmed death ligand-1 expression in LEL-HCC.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Biomarcadores Tumorais / Carcinoma Hepatocelular / Antígeno B7-H1 / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans Idioma: En Revista: Ann. hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: México
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Biomarcadores Tumorais / Carcinoma Hepatocelular / Antígeno B7-H1 / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans Idioma: En Revista: Ann. hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: México