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Virus de West Nile. Nuevo virus emergente en medicina transfusional / West Nile Virus. A new emergent virus in transfusional medicine
Blejer, Jorgelina L; Salamone, Horacio J.
Afiliação
  • Blejer, Jorgelina L; Fundación Favaloro. Departamento de Investigación Clínica. Sección Medicina Transfusional. Ciudad Autónoma de Buenos Aires. Argentina
  • Salamone, Horacio J; Fundación Favaloro. Departamento de Investigación Clínica. Sección Medicina Transfusional. Ciudad Autónoma de Buenos Aires. Argentina
Rev. argent. transfus ; 30(1): 19-30, ene.-mar. 2004. tab
Article em Es | BINACIS | ID: bin-2884
Biblioteca responsável: AR1.1
ABSTRACT
West Nile virus is a member of the Flaviviridae family. It was first isolated in Uganda and is indigenous to Africa, Asia, Australia and southern Europe. In recent years, local epidemics have been reported in Romania, Russia and Israel. In 1999 the virus presented a rapid emergence in North America and until November 2002 it has caused over 4,100 symptomatic infections in humans, of whom more than 240 have died. The life cycle of the virus includes mosquitoes as vectors with birds as amplifying viremic vertebrate hosts. Human, horses and other animals serve as dead-end hosts. Most infections are mild, with symptoms primarily being fever, headache, and myalgias. People older than 50 years are at highest risk of severe disease, which include encephalomyelitis. In 2002, 5 new modes of transmission were recognized blood transfusion, organ transplantation, breast-feeding, transplacental transmission and occupational exposure in laboratory workers. Regarding blood transfusion, during the 2002 West Nile virus epidemic in the United States, 23 patients were confirmed to have acquired West Nile virus through transfused red cells, platelets or fresh-frozen plasma. Currently, there is no specific drug treatment or vaccine against the infection, and avoiding mosquito bites is the best way to protect against the disease. (AU)
Assuntos
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Coleções: 06-national / AR Base de dados: BINACIS Assunto principal: Febre do Nilo Ocidental / Vírus do Nilo Ocidental Tipo de estudo: Diagnostic_studies País/Região como assunto: America do norte Idioma: Es Revista: Rev. argent. transfus Ano de publicação: 2004 Tipo de documento: Article
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Coleções: 06-national / AR Base de dados: BINACIS Assunto principal: Febre do Nilo Ocidental / Vírus do Nilo Ocidental Tipo de estudo: Diagnostic_studies País/Região como assunto: America do norte Idioma: Es Revista: Rev. argent. transfus Ano de publicação: 2004 Tipo de documento: Article