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Influence of ethanol and morphine on pain perception evoked by deep tissue injury
Gameiro, Gustavo Hauber; Arthuri, Mariana Trevisani; Tambeli, Claudia Herrera; Veiga, Maria Cecília Ferraz de Arruda.
Afiliação
  • Gameiro, Gustavo Hauber; University of Campinas. Faculty of Dentistry of Piracicaba. Department of Physiology. Laboratory of Orofacial Pain. BR
  • Arthuri, Mariana Trevisani; University of Campinas. Faculty of Dentistry of Piracicaba. Department of Physiology. Laboratory of Orofacial Pain. BR
  • Tambeli, Claudia Herrera; University of Campinas. Faculty of Dentistry of Piracicaba. Department of Physiology. Laboratory of Orofacial Pain. BR
  • Veiga, Maria Cecília Ferraz de Arruda; University of Campinas. Faculty of Dentistry of Piracicaba. Department of Physiology. Laboratory of Orofacial Pain. BR
RBCF, Rev. bras. ciênc. farm. (Impr.) ; 40(3): 317-325, jul.-set. 2004. ilus, graf
Article em En | LILACS | ID: lil-420679
Biblioteca responsável: BR40.1
RESUMO
The aim of this study was to evaluate the effect of ethanol and morphine on nociceptive behavioral responses evoked by the injection of formalin into the temporomandibular joint region of rats (the TMJ formalin test). In experiment 1, animals were given an ethanol solution (6.5 por cento) or tap water to drink for 4 and 10 days, before the procedure for TMJ pain. In the group treated for 4 days, significant analgesia was observed in the TMJ formalin test, whereas the group treated for 10 days did not show this effect, revealing the development of tolerance to ethanol antinociceptive effects. In experiment 2, animals were submitted to chronic regimen of ethanol (6.5 por cento for 10 days did not show this effect, revealing the development of tolerance to ethanol antinociceptive effects...
Assuntos
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Articulação Temporomandibular / Medição da Dor / Nociceptores / Etanol / Morfina Limite: Animals Idioma: En Revista: RBCF, Rev. bras. ciênc. farm. (Impr.) Assunto da revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Ano de publicação: 2004 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Articulação Temporomandibular / Medição da Dor / Nociceptores / Etanol / Morfina Limite: Animals Idioma: En Revista: RBCF, Rev. bras. ciênc. farm. (Impr.) Assunto da revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Ano de publicação: 2004 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil