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Association between left ventricular diastolic dysfunction and severity of chronic obstructive pulmonary disease
Caram, Laura Miranda de Oliveira; Ferrari, Renata; Naves, Cristiane Roberta; Tanni, Suzana Erico; Coelho, Liana Sousa; Zanati, Silméia Garcia; Minicucci, Marcos Ferreira; Godoy, Irma.
Afiliação
  • Caram, Laura Miranda de Oliveira; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Ferrari, Renata; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Naves, Cristiane Roberta; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Tanni, Suzana Erico; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Coelho, Liana Sousa; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Zanati, Silméia Garcia; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Minicucci, Marcos Ferreira; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
  • Godoy, Irma; Universidade Estadual Paulista. Faculdade de Medicina de Botucatu. Botucatu. BR
Clinics ; 68(6): 772-776, jun. 2013. tab
Article em En | LILACS | ID: lil-676931
Biblioteca responsável: BR1.1
ABSTRACT

OBJECTIVES:

The prevalence of electrocardiographic and echocardiographic abnormalities in chronic obstructive pulmonary disease according to disease severity has not yet been established. The aim of this study was to assess the prevalence of electrocardiographic and echocardiographic abnormalities in chronic obstructive pulmonary disease patients according to disease severity.

METHODS:

The study included 25 mild/moderate chronic obstructive pulmonary disease patients and 25 severe/very severe chronic obstructive pulmonary disease patients. All participants underwent clinical evaluation, spirometry and electrocardiography/echocardiography.

RESULTS:

Electrocardiography and echocardiography showed Q-wave alterations and segmental contractility in five (10%) patients. The most frequent echocardiographic finding was mild left diastolic dysfunction (88%), independent of chronic obstructive pulmonary disease stage. The proportion of right ventricular overload (p<0.05) and blockage of the anterosuperior division of the left bundle branch were higher in patients with greater obstruction. In an echocardiographic analysis, mild/moderate chronic obstructive pulmonary disease patients showed more abnormalities in segmental contractility (p<0.05), whereas severe/very severe chronic obstructive pulmonary disease patients showed a higher prevalence of right ventricular overload (p<0.05), increased right cardiac chamber (p<0.05) and higher values of E-wave deceleration time (p<0.05). Age, sex, systemic arterial hypertension, C-reactive protein and disease were included as independent variables in a multiple linear regression; only disease severity was predictive of the E-wave deceleration time [r2 = 0.26, p = 0.01].

CONCLUSION:

Chronic obstructive pulmonary disease patients have a high prevalence of left ventricular diastolic dysfunction, which ...
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Disfunção Ventricular Esquerda / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2013 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Disfunção Ventricular Esquerda / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2013 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil