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Alterations of the gastric stump and not resected stomach mucosa after truncal vagotomy in rats
Rodrigues, Paulo Antonio; Naresse, Luiz Eduardo; Minossi, Jose Guilherme; Hasimoto, Claudia Nishida.
Afiliação
  • Rodrigues, Paulo Antonio; Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Cirurgia e Ortopedia. Botucatu. BR
  • Naresse, Luiz Eduardo; Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Cirurgia e Ortopedia. Botucatu. BR
  • Minossi, Jose Guilherme; Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Cirurgia e Ortopedia. Botucatu. BR
  • Hasimoto, Claudia Nishida; Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Cirurgia e Ortopedia. Botucatu. BR
Acta cir. bras ; 29(2): 99-103, 02/2014. graf
Article em En | LILACS | ID: lil-702521
Biblioteca responsável: BR1.1
ABSTRACT
To evaluate morphological changes of the gastric stump and not resected stomach mucosa after the completion of truncal vagotomy.

METHODS:

Eighty male Wistar rats were divided into four groups CT, TV, RY and RYTV. In CT group, abdominal viscera were manipulated and the abdominal cavity was closed, in TV vagal trunks were isolated and sectioned, in RY a partial Roux-en-Y gastrectomy was performed and in RYTV the vagal trunks were sectioned and a partial Roux-en-Y gastrectomy was performed. At the 54th week after surgery, the rats were euthanized. The findings were submitted to histological analyses.

RESULTS:

None macroscopic or histological alterations in groups TV and CT was observed. Specimens from RY and RYTV groups did not show alterations in the gastric stump mucosa. At the jejunal side of the gastroenterostomy we found shallow ulcerative lesions always single, well-defined and with variable diameter 3 to 6 mm, six times in the RY group and none in the RYTV group (RY>RYTV, p=0.008). Neoplastic or preneoplastic lesions were not diagnosed in all groups.

CONCLUSION:

Truncal vagotomy is a safe and non-carcinogenic method in not resected and partially resected stomach.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Estômago / Vagotomia / Mucosa Gástrica Limite: Animals Idioma: En Revista: Acta cir. bras Assunto da revista: CIRURGIA GERAL / Procedimentos Cir£rgicos Operat¢rios Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Estômago / Vagotomia / Mucosa Gástrica Limite: Animals Idioma: En Revista: Acta cir. bras Assunto da revista: CIRURGIA GERAL / Procedimentos Cir£rgicos Operat¢rios Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil