Carcinocythemia in a patient with rhabdomyosarcoma
Bol. Asoc. Méd. P. R
; 83(1): 13-6, ene. 1991. tab
Article
em En
| LILACS
| ID: lil-97781
Biblioteca responsável:
BR1.1
RESUMO
Solid tumor cells are rarely seen in peripheral blood smears. When this occurs the term carcinocythemia is used. This report describes an 18 years old female who presented with a painless lump in the labia majora associated with pancytopenia. Tumor cells were identified int he peripheral blood smear and the bone marrow aspirate showed a predominant population of small round vacuolated primitive cells, many of which formed clumps of varying sizes. Biopsies of the vulvar mass and bone marrow were interpreted as alveolar rhabdomyosarcoma. Review of the literature revealed 12 previously reported cases in whom carcinocythemia had been documented; rhabdomyosarcoma was the specific cell type involved in only two of these. The median time between detection of the leukemic phase of the tumor and death was 8.5 weeks, reflecting the fact that carcinocythemia, when it occurs, represents the terminal event of the disease. To our knowledge, our case is the third well documented case of rhabdomyosarcoma in leukemic phase so far reported. The clinical evolution as well as the management of this patient will be described in detail along with a review of the partinent available literature
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Rabdomiossarcoma
/
Neoplasias Vulvares
/
Células Neoplásicas Circulantes
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Bol. Asoc. Méd. P. R
Assunto da revista:
MEDICINA
Ano de publicação:
1991
Tipo de documento:
Article
País de publicação:
Porto Rico