Mifepristone-misoprostol medical abortion: home administration of misoprostol in Guadeloupe.
Contraception
; 60(3): 167-72, 1999 Sep.
Article
em En
| MEDLINE
| ID: mdl-10640161
ABSTRACT
PIP: This paper presents a prospective study of home administration and a one-treatment-visit regimen of mifepristone-misoprostol for medical abortion in Guadeloupe. The administration of this contraceptive method usually requires a standard 3-clinic visit regimen, which would sometimes lead to discontinuation of the abortion process. The study consisted of 92 medical abortion cases conducted over a 13-month period. The intervention involved a 1-day treatment visit with patients receiving 600 mg of mifepristone and instructions on ingesting 2 tablets (400 mcg) of misoprostol orally after 2 days and another 200 mcg misoprostol if bleeding had not occurred within 6-12 hours. A follow-up was conducted among these women after 10-15 days of initial clinic visit and contraceptive administration. The total success rate was 95.4% in comparison with those who received a 3-clinic visit regimen and the statistical result of a study conducted in the US. Several adverse effects have been associated with the administration of abortive methods, which include bleeding (19.6% in mifepristone users and 68.2% in misoprostol users) and vomiting. Strict monitoring of mifepristone and misoprostol distribution and patient follow-up was ensured by French legislators. The authors conclude that home administration of misoprostol must be made available to women in developing countries.
Palavras-chave
Abortion, Drug Induced; Abortion, Induced; Americas; Biology; Caribbean; Communication; Developing Countries; Endocrine System; Family Planning; Fertility Control, Postconception; Guadeloupe; Home Visits; Hormone Antagonists; Hormones; Misoprostol; North America; Physiology; Prospective Studies; Prostaglandins; Prostaglandins, Synthetic; Research Methodology; Research Report; Ru-486; Studies
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Autoadministração
/
Abortivos não Esteroides
/
Abortivos Esteroides
/
Mifepristona
/
Misoprostol
Tipo de estudo:
Guideline
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
País/Região como assunto:
Caribe
/
Guadalupe
Idioma:
En
Revista:
Contraception
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Níger
País de publicação:
Estados Unidos