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Personalized dosing via pharmacokinetic monitoring of 5-fluorouracil might reduce toxicity in early- or late-stage colorectal cancer patients treated with infusional 5-fluorouracil-based chemotherapy regimens.
Kline, Christina Leah B; Schiccitano, Angelique; Zhu, Junjia; Beachler, Cheryl; Sheikh, Hassan; Harvey, Harold A; Mackley, Heath B; McKenna, Kevin; Staveley-O'Carroll, Kevin; Poritz, Lisa; Messaris, Evangelos; Stewart, David; Sivik, Jeffrey; El-Deiry, Wafik S.
Afiliação
  • Kline CL; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA.
  • Schiccitano A; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA.
  • Zhu J; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA.
  • Beachler C; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA.
  • Sheikh H; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA.
  • Harvey HA; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA.
  • Mackley HB; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA; Division of Radiation Oncology, Department of Radiology, Penn State College of Medicine, Hershey, PA.
  • McKenna K; Department of Surgery, Penn State College of Medicine, Hershey, PA.
  • Staveley-O'Carroll K; Department of Surgery, Penn State College of Medicine, Hershey, PA.
  • Poritz L; Department of Surgery, Penn State College of Medicine, Hershey, PA.
  • Messaris E; Department of Surgery, Penn State College of Medicine, Hershey, PA.
  • Stewart D; Department of Surgery, Penn State College of Medicine, Hershey, PA.
  • Sivik J; Department of Pharmacology, Penn State College of Medicine, Hershey, PA.
  • El-Deiry WS; Hematology/Oncology Division, Department of Medicine, Penn State College of Medicine, Hershey, PA. Electronic address: weldeiry@hmc.psu.edu.
Clin Colorectal Cancer ; 13(2): 119-26, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24461492

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Camptotecina / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Monitoramento de Medicamentos Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Clin Colorectal Cancer Assunto da revista: GASTROENTEROLOGIA / NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Panamá País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Camptotecina / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Monitoramento de Medicamentos Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Clin Colorectal Cancer Assunto da revista: GASTROENTEROLOGIA / NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Panamá País de publicação: Estados Unidos