Autofagia/efeitos dos fármacos; Bleomicina/farmacologia; Cisteína Endopeptidases/metabolismo; Homeostase/efeitos dos fármacos; Fibrose Pulmonar Idiopática/metabolismo; Animais; Apoptose/genética; Autofagia/fisiologia; Proteínas Relacionadas à Autofagia; Cisteína Endopeptidases/genética; Citocinas/genética; Citocinas/metabolismo; Células Epiteliais/citologia; Células Epiteliais/efeitos dos fármacos; Expressão Gênica/efeitos dos fármacos; Fibrose Pulmonar Idiopática/induzido quimicamente; Camundongos Knockout

ACTA2, actin, α 2, smooth muscle, aorta; ATG3, autophagy-related 3; ATG4B; ATG4B, autophagy-related 4B; ATG5, autophagy-related 5; ATG7, autophagy-related 7; ATG9B, autophagy-related 9B; BAX, BCL2-associated X protein; CASP3, caspase 3, apoptosis-related cysteine peptidase; CAV1, caveolin 1, caveolae protein, 22kDa; CCL3, chemokine (C-C motif) ligand 3; CXCL1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity α); CXCR2, chemokine (C-X-C motif) receptor 2; DRAM2, DNA-damage regulated autophagy modulator 2; GFP-LC3B, green fluorescent protein-LC3B; IFNG, interferon, gamma; IL12B, interleukin 12B; IL13, interleukin 13; IPF, idiopathic pulmonary fibrosis; MAP1LC3B/LC3B, microtubule-associated protein 1 light chain 3 ß; RELA, v-rel reticuloendotheliosis viral oncogene homolog A; SQSTM1, sequestosome 1; TGFB1, transforming growth factor, ß 1; TGFBR2, transforming growth factor, ß receptor II (70/80kDa); TNF, tumor necrosis factor; TUBB4, tubulin, ß 4, class IV; WT, wild type; autophagin-1; autophagy; cysteine peptidase; epithelial cell; idiopathic pulmonary fibrosis; lung fibrosis