ß-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.

Piedrahita, Diego; Castro-Alvarez, John Fredy; Boudreau, Ryan L; Villegas-Lanau, Andres; Kosik, Kenneth S; Gallego-Gomez, Juan Carlos; Cardona-Gómez, Gloria Patricia

Piedrahita, Diego; Castro-Alvarez, John Fredy; Boudreau, Ryan L; Villegas-Lanau, Andres; Kosik, Kenneth S; Gallego-Gomez, Juan Carlos; Cardona-Gómez, Gloria Patricia.

Afiliação

Piedrahita D; Cellular and Molecular Neurobiology Area, Viral Vector Core and Gene Therapy, University of Antioquia Medellin, Antioquia, Colombia.
Castro-Alvarez JF; Cellular and Molecular Neurobiology Area, Viral Vector Core and Gene Therapy, University of Antioquia Medellin, Antioquia, Colombia.
Boudreau RL; Internal Medicine, University of Iowa Iowa, IA, USA.
Villegas-Lanau A; Neurobank, Neuroscience Group of Antioquia, Faculty of Medicine, SIU, University of Antioquia Medellín, Colombia.
Kosik KS; Department of Molecular Cellular Developmental Biology, Neuroscience Research Institute, University of California Santa Barbara Santa Barbara, CA, USA.
Gallego-Gomez JC; Cellular and Molecular Neurobiology Area, Viral Vector Core and Gene Therapy, University of Antioquia Medellin, Antioquia, Colombia.
Cardona-Gómez GP; Cellular and Molecular Neurobiology Area, Viral Vector Core and Gene Therapy, University of Antioquia Medellin, Antioquia, Colombia.

Front Cell Neurosci ; 9: 498, 2015.

Article em En | MEDLINE | ID: mdl-26778963

Palavras-chave

Alzheimer's disease; autophagy; chaperones; lipid rafts; tauopathy; ß-secretase 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Cell Neurosci Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Suíça

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