Immunogenicity and Protective Response Induced by Recombinant Plasmids Based on the BAB1_0267 and BAB1_0270 Open Reading Frames of <i>Brucella abortus</i> 2308 in BALB/c Mice.

Gómez, Leonardo A; Alvarez, Francisco I; Fernández, Pablo A; Flores, Manuel R; Molina, Raúl E; Coloma, Roberto F; Oñate, Angel A

Immunogenicity and Protective Response Induced by Recombinant Plasmids Based on the BAB1_0267 and BAB1_0270 Open Reading Frames of Brucella abortus 2308 in BALB/c Mice.

Gómez, Leonardo A; Alvarez, Francisco I; Fernández, Pablo A; Flores, Manuel R; Molina, Raúl E; Coloma, Roberto F; Oñate, Angel A.

Afiliação

Gómez LA; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.
Alvarez FI; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.
Fernández PA; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.
Flores MR; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.
Molina RE; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.
Coloma RF; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.
Oñate AA; Laboratory of Molecular Immunology, Department of Immunology, Faculty of Biological Sciences, Universidad de Concepción Concepción, Chile.

Front Cell Infect Microbiol ; 6: 117, 2016.

Article em En | MEDLINE | ID: mdl-27747197

Assuntos

Brucella abortus/genética; Brucella abortus/imunologia; Brucelose/imunologia; Brucelose/prevenção & controle; DNA Recombinante; Fases de Leitura Aberta/genética; Plasmídeos/genética; Vacinas de DNA; Animais; Proteínas de Bactérias/genética; Proteínas de Bactérias/imunologia; Contagem de Colônia Microbiana; Citocinas/análise; DNA Bacteriano; Modelos Animais de Doenças; Feminino; Genes Bacterianos/genética; Imunoglobulina G/biossíntese; Interferon gama/análise; Metaloendopeptidases; Camundongos; Camundongos Endogâmicos BALB C; Fagócitos/imunologia; Sobrevida; Vacinação

Palavras-chave

DNA vaccines; Src homology 3 domain; brucellosis; interferon gamma; zinc-dependent metalloproteinase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmídeos / Brucella abortus / Brucelose / DNA Recombinante / Fases de Leitura Aberta / Vacinas de DNA Limite: Animals Idioma: En Revista: Front Cell Infect Microbiol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Chile País de publicação: Suíça

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