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Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Hertzog, Jonny; Dias Junior, Antonio Gregorio; Rigby, Rachel E; Donald, Claire L; Mayer, Alice; Sezgin, Erdinc; Song, Chaojun; Jin, Boquan; Hublitz, Philip; Eggeling, Christian; Kohl, Alain; Rehwinkel, Jan.
Afiliação
  • Hertzog J; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Dias Junior AG; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Rigby RE; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Donald CL; MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, UK.
  • Mayer A; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Sezgin E; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Song C; Department of Immunology, The Fourth Military Medical University, Xi'an, PR China.
  • Jin B; Department of Immunology, The Fourth Military Medical University, Xi'an, PR China.
  • Hublitz P; Genome Engineering Facility, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Eggeling C; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Kohl A; MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, UK.
  • Rehwinkel J; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Eur J Immunol ; 48(7): 1120-1136, 2018 07.
Article em En | MEDLINE | ID: mdl-29572905
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Interferon Tipo I / Proteínas não Estruturais Virais / Fator de Transcrição STAT1 / Fator de Transcrição STAT2 / Proteína DEAD-box 58 Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Eur J Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Alemanha
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Interferon Tipo I / Proteínas não Estruturais Virais / Fator de Transcrição STAT1 / Fator de Transcrição STAT2 / Proteína DEAD-box 58 Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Eur J Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Alemanha