Engineering metabolic pathways in <i>Amycolatopsis japonicum</i> for the optimization of the precursor supply for heterologous brasilicardin congeners production.

Schwarz, Paul N; Roller, Luisa; Kulik, Andreas; Wohlleben, Wolfgang; Stegmann, Evi

Engineering metabolic pathways in Amycolatopsis japonicum for the optimization of the precursor supply for heterologous brasilicardin congeners production.

Schwarz, Paul N; Roller, Luisa; Kulik, Andreas; Wohlleben, Wolfgang; Stegmann, Evi.

Afiliação

Schwarz PN; Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), Eberhard Karls University Tübingen, Tübingen, Germany.
Roller L; Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), Eberhard Karls University Tübingen, Tübingen, Germany.
Kulik A; Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), Eberhard Karls University Tübingen, Tübingen, Germany.
Wohlleben W; Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), Eberhard Karls University Tübingen, Tübingen, Germany.
Stegmann E; German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.

Synth Syst Biotechnol ; 3(1): 56-63, 2018 Mar.

Article em En | MEDLINE | ID: mdl-29911199

Palavras-chave

3HBA, 3-hydroxy-benzoate; Aact, acetoacetyl CoA thiolase; BraA, brasilicardin A; BraB, brasilicardin B; BraC, brasilicardin C; BraC-agl, brasilicardin C aglycon; BraD, brasilicardin D; BraD-agl, brasilicardin D aglycon; DMAPP, dimethylallyl diphosphate; FPP, farnesyl diphosphate; Fpps, farnesyl diphosphate synthase; GGPP, geranylgeranyl diphosphate; GPP, geranyl diphosphate; Ggpps, geranylgeranyl diphosphate synthase; GlcNAc, N-acetylglucosamine; Gpps, geranyl diphosphate synthase; IPP, isopentenyl diphosphate; Idi, isopentenyl diphosphate synthase; Isoprenoids; MEP, Methylerythritol 4-phosphate; MVA, mevalonate; Mevalonate pathway; Norcardia terpenica IFM0406; Prenyltransferases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: Synth Syst Biotechnol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: China

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