MicroRNA-23b and microRNA-27b plus flutamide treatment enhances apoptosis rate and decreases CCNG1 expression in a castration-resistant prostate cancer cell line.

Pimenta, Ruan Ca; Viana, Nayara I; Amaral, Gabriela Q; Park, Rubens; Morais, Denis R; Pontes, José; Guimaraes, Vanessa R; Camargo, Juliana A; Leite, Kátia Rm; Nahas, William C; Srougi, Miguel; Reis, Sabrina T

Pimenta, Ruan Ca; Viana, Nayara I; Amaral, Gabriela Q; Park, Rubens; Morais, Denis R; Pontes, José; Guimaraes, Vanessa R; Camargo, Juliana A; Leite, Kátia Rm; Nahas, William C; Srougi, Miguel; Reis, Sabrina T.

Afiliação

Pimenta RC; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Viana NI; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Amaral GQ; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Park R; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Morais DR; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Pontes J; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Guimaraes VR; 2 Uro-Oncology Group, Urology Department, University of Sao Paulo Medical School and Institute of Cancer Estate of Sao Paulo (ICESP), Sao Paulo, Brazil.
Camargo JA; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Leite KR; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Nahas WC; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Srougi M; 2 Uro-Oncology Group, Urology Department, University of Sao Paulo Medical School and Institute of Cancer Estate of Sao Paulo (ICESP), Sao Paulo, Brazil.
Reis ST; 1 Laboratory of Medical Investigation (LIM55), Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil.

Tumour Biol ; 40(11): 1010428318803011, 2018 Nov.

Article em En | MEDLINE | ID: mdl-30400755

Assuntos

Apoptose/efeitos dos fármacos; Apoptose/genética; Ciclina G1/genética; Flutamida/metabolismo; MicroRNAs/genética; Neoplasias de Próstata Resistentes à Castração/tratamento farmacológico; Neoplasias de Próstata Resistentes à Castração/genética; Linhagem Celular Tumoral; Fase G1/efeitos dos fármacos; Fase G1/genética; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Masculino; Pessoa de Meia-Idade; Mitose/efeitos dos fármacos; Mitose/genética; Próstata/efeitos dos fármacos; Fase de Repouso do Ciclo Celular/efeitos dos fármacos; Fase de Repouso do Ciclo Celular/genética; Transfecção/métodos

Palavras-chave

CCNG1; MicroRNAs; castration-resistant prostate cancer; flutamide; miR-23b; miR-27b

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / MicroRNAs / Ciclina G1 / Neoplasias de Próstata Resistentes à Castração / Flutamida Limite: Humans / Male / Middle aged Idioma: En Revista: Tumour Biol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda

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