Pilocarpine-induced seizures associate with modifications of LSD1/CoREST/HDAC1/2 epigenetic complex and repressive chromatin in mice hippocampus.

Noches, Verónica; Rivera, Carlos; González, Marcela P; Merello, Gianluca; Olivares-Costa, Montserrat; Andrés, María Estela

Noches, Verónica; Rivera, Carlos; González, Marcela P; Merello, Gianluca; Olivares-Costa, Montserrat; Andrés, María Estela.

Afiliação

Noches V; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rivera C; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
González MP; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Merello G; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Olivares-Costa M; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Andrés ME; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.

Biochem Biophys Rep ; 25: 100889, 2021 Mar.

Article em En | MEDLINE | ID: mdl-33426312

Palavras-chave

CoREST, Corepressor for element-1 silencing transcription factor; H3K4me2; H3K4me2, histone H3 lysine 4 dimethylation; H3K4me3, histone H3 lysine 4 trimethylation; H3K9me2; H3K9me2, histone H3 lysine 9 dimethylation; H3K9me3, histone H3 lysine 9 trimethylation; H3ac, Histone H3 acetylated; HDAC, Histone deacetylase; HP1α, heterochromatin protein 1α; LCH Complex, LSD1/CoREST/HDACs complex; LCH complex; LSD1, lysine-specific demethylase 1; Muscarinic receptors; Pilo, Pilocarpine; Pilocarpine; SMN, Scopolamine Methyl Nitrate; Status epilepticus; TLE, Temporal Lobe Epilepsy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Chile País de publicação: Holanda

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