(m-CF<sub>3</sub>-PhSe)<sub>2</sub> benefits against anxiety-like phenotype associated with synaptic plasticity impairment and NMDAR-mediated neurotoxicity in young mice exposed to a lifestyle model.

Müller, Sabrina G; Jardim, Natália S; Lutz, Guilherme; Zeni, Gilson; Nogueira, Cristina W

(m-CF₃-PhSe)₂ benefits against anxiety-like phenotype associated with synaptic plasticity impairment and NMDAR-mediated neurotoxicity in young mice exposed to a lifestyle model.

Müller, Sabrina G; Jardim, Natália S; Lutz, Guilherme; Zeni, Gilson; Nogueira, Cristina W.

Afiliação

Müller SG; Laboratory of Synthesis, Reactivity, Pharmacological and Toxicological Evaluation of Organochalcogen Compounds, Department of Biochemistry and Molecular Biology, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.
Jardim NS; Laboratory of Synthesis, Reactivity, Pharmacological and Toxicological Evaluation of Organochalcogen Compounds, Department of Biochemistry and Molecular Biology, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.
Lutz G; Laboratory of Synthesis, Reactivity, Pharmacological and Toxicological Evaluation of Organochalcogen Compounds, Department of Biochemistry and Molecular Biology, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.
Zeni G; Laboratory of Synthesis, Reactivity, Pharmacological and Toxicological Evaluation of Organochalcogen Compounds, Department of Biochemistry and Molecular Biology, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.
Nogueira CW; Laboratory of Synthesis, Reactivity, Pharmacological and Toxicological Evaluation of Organochalcogen Compounds, Department of Biochemistry and Molecular Biology, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil. Electronic address: criswn@uf

Chem Biol Interact ; 378: 110486, 2023 Jun 01.

Article em En | MEDLINE | ID: mdl-37054933

Assuntos

Ansiolíticos; Compostos Organosselênicos; Camundongos; Animais; Masculino; Ansiolíticos/farmacologia; Atividade Motora; Ansiedade/tratamento farmacológico; Transtornos de Ansiedade; Fenótipo; Compostos Organosselênicos/farmacologia; Derivados de Benzeno/farmacologia

Palavras-chave

Anxiety; Ethanol; Food; Neurotoxicity; Selenium

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ansiolíticos / Compostos Organosselênicos Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Chem Biol Interact Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irlanda

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