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Malignant tumors affecting the head and neck region in ancient times: Comprehensive study of the CRAB Database.
Aulestia-Viera, Patricia Verónica; Rodrigues-Fernandes, Carla Isabelly; Brandão, Thaís Bianca; Rocha, André Caroli; Vargas, Pablo Agustin; Lopes, Marcio Ajudarte; Johnson, Newell Walter; Kowalski, Luiz Paulo; Ribeiro, Ana Carolina Prado; Santos-Silva, Alan Roger.
Afiliação
  • Aulestia-Viera PV; Universidade de São Paulo - USP, Medical School, Clínicas Hospital, São Paulo, SP, Brazil.
  • Rodrigues-Fernandes CI; Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Oral Diagnosis Department, Piracicaba, SP, Brazil.
  • Brandão TB; Universidade de São Paulo - USP, School of Medicine, Dental Oncology Service, São Paulo, SP, Brazil.
  • Rocha AC; Universidade de São Paulo - USP, Medical School, Clínicas Hospital, São Paulo, SP, Brazil.
  • Vargas PA; Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Oral Diagnosis Department, Piracicaba, SP, Brazil.
  • Lopes MA; Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Oral Diagnosis Department, Piracicaba, SP, Brazil.
  • Johnson NW; Griffith University, Queensland and School of Medicine, Queensland, Australia.
  • Kowalski LP; Universidade de São Paulo - USP, Medical School, Head and Neck Surgery Department, São Paulo, SP, Brazil.
  • Ribeiro ACP; Universidade de São Paulo - USP, School of Medicine, Dental Oncology Service, São Paulo, SP, Brazil.
  • Santos-Silva AR; Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Oral Diagnosis Department, Piracicaba, SP, Brazil.
Braz Oral Res ; 38: e014, 2024.
Article em En | MEDLINE | ID: mdl-38198312
ABSTRACT
In the modern world, cancer is a growing cause of mortality, but archeological studies have shown that it is not exclusive to modern populations. The aim of this study is to examine the epidemiologic, social, and clinicopathologic features of head and neck cancers in ancient populations. To do this, we extracted all records that described malignant lesions in the head and neck region available in the Cancer Research in Ancient Bodies Database (CRAB). The estimated age, sex, physical condition of the remains (skeletonized, mummified), anatomic location of tumors, geographic location, chronology, tumor type, and methods of tumor diagnosis were collected. One hundred and sixty-seven cases were found, mostly originating from Europe (51.5%). Most records were of adults between 35 and 49 years of age (37.7%). The most involved site was the skullcap (60.4%), and the most common malignancies were metastases to the bone (65.3%) and multiple myeloma (17.4%). No primary soft tissue malignancies were registered. The results of our study indicate that head and neck cancers were present in ancient civilizations, at least since 500,000 BCE. The available data can help to improve the current understanding of the global distribution of head and neck cancer and its multidimensional impacts on populations in the contemporary world.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cabeça / Neoplasias de Cabeça e Pescoço Limite: Adult / Humans Idioma: En Revista: Braz Oral Res Assunto da revista: ODONTOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cabeça / Neoplasias de Cabeça e Pescoço Limite: Adult / Humans Idioma: En Revista: Braz Oral Res Assunto da revista: ODONTOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil