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Validity of the GLIM criteria for the diagnosis of malnutrition in patients with colorectal cancer: A multicenter study on the diagnostic performance of different indicators of reduced muscle mass and disease severity.
Dos Santos, Ana Luiza Soares; Santos, Bárbara Chaves; Frazão, Luísa Nascimento; Miranda, Ana Lúcia; Fayh, Ana Paula Trussardi; Silva, Flávia Moraes; Gonzalez, Maria Cristina; Correia, Maria Isabel Toulson Davisson; Souza, Nilian Carla; Anastácio, Lucilene Rezende; Maurício, Sílvia Fernandes.
Afiliação
  • Dos Santos ALS; Universidade Federal de Minas Gerais, Postgraduate Program in Food Science, Belo Horizonte, Brazil.
  • Santos BC; Universidade Federal de Minas Gerais, Postgraduate Program in Food Science, Belo Horizonte, Brazil.
  • Frazão LN; Universidade Federal de Ouro Preto, School of Nutrition, Ouro Preto, MG, Brazil.
  • Miranda AL; Universidade Federal do Rio Grande do Norte, Postgraduate Program in Health Sciences, Health Sciences Center, Natal, Brazil.
  • Fayh APT; Universidade Federal do Rio Grande do Norte, Postgraduate Program in Health Sciences, Health Sciences Center, Natal, Brazil.
  • Silva FM; Universidade Federal de Ciências da Saúde de Porto Alegre, Department of Nutrition, Porto Alegre, Brazil.
  • Gonzalez MC; Postgraduate Program in Food and Nutrition, Federal University of Pelotas, Rio Grande do Sul, Pelotas, Brazil.
  • Correia MITD; Department of Surgery, Medical School, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
  • Souza NC; Brazilian National Cancer Institute, Rio de Janeiro, Brazil.
  • Anastácio LR; Universidade Federal de Minas Gerais, Postgraduate Program in Food Science, Belo Horizonte, Brazil. Electronic address: lucilene.rezende@gmail.com.
  • Maurício SF; Universidade Federal de Minas Gerais, Postgraduate Program in Food Science, Belo Horizonte, Brazil. Electronic address: silviafmauricio@gmail.com.
Nutrition ; 119: 112324, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38215671
ABSTRACT

OBJECTIVES:

To assess the concurrent and predictive validity of different combinations of Global Leadership Initiative on Malnutrition (GLIM) criteria in patients with colorectal cancer considering different indicators of reduced muscle mass (MM) and the effects of the disease.

METHODS:

A secondary analysis with patients with colorectal cancer. The reduced MM was assessed by arm muscle area, arm muscle circumference, calf circumference, fat-free mass index, skeletal muscle index (SMI) and skeletal muscle. Cancer diagnosis or disease staging (TNM) was considered for the etiologic criterion referred to as the effect of the disease. The other phenotypic and etiologic criteria were also evaluated, and we analyzed 13 GLIM combinations. Concurrent validity between GLIM criteria and Patient-Generated Subjective Global Assessment was evaluated. Logistic and Cox regression were used in the predictive validation.

RESULTS:

For concurrent validity (n = 208), most GLIM combinations (n = 6; 54.5%) presented a moderate agreement with Patient-Generated Subjective Global Assessment and none showed satisfactory sensitivity and specificity (>80%). Reduced MM evaluated by SMI and SMI were present in the GLIM combinations associated with postoperative complications (odds ratio, ≥2.0), independent of other phenotypic and etiologic criteria. The combinations with reduced MM considering any method and fixed phenotypic criteria and TNM were associated with mortality (hazard ratio, ≥2.0).

CONCLUSIONS:

Satisfactory concurrent validity was not verified. The GLIM diagnosis of malnutrition was associated with postoperative complications and mortality.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Desnutrição Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Aspecto: Determinantes_sociais_saude / Patient_preference Limite: Humans Idioma: En Revista: Nutrition Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Desnutrição Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Aspecto: Determinantes_sociais_saude / Patient_preference Limite: Humans Idioma: En Revista: Nutrition Assunto da revista: CIENCIAS DA NUTRICAO Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos