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Mortality in patients with severe COVID-19 who underwent tracheostomy due to prolonged mechanical ventilation.
Romero, Carlos-Miguel; Gajardo, Abraham Ij; Cruz, Amalia; Tobar, Eduardo; Godoy, Jaime; Medel, Nicolás; Zamorano, Ricardo; Rappoport, Daniel; Rojas, Verónica; Herrera, María-Cristina; Cornejo, Rodrigo; Luengo, Cecilia; Estuardo, Nivia.
Afiliação
  • Romero CM; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Gajardo AI; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Cruz A; School of Medicine, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Tobar E; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Godoy J; Department of Anesthesiology and Perioperative Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Medel N; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Zamorano R; Department of Otorhinolaryngology, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Rappoport D; Department of Surgery, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Rojas V; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Herrera MC; Department of Nursing, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Cornejo R; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Luengo C; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
  • Estuardo N; Critical Care Unit, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Rev Med Chil ; 151(2): 151-159, 2023 Feb.
Article em En | MEDLINE | ID: mdl-38293850
ABSTRACT

BACKGROUND:

The usefulness of tracheostomy has been questioned in patients with COVID-19 and prolonged invasive mechanical ventilation (IMV).

AIM:

To compare the 90-day mortality rate of patients who underwent a tracheostomy due prolonged IMV with those that did not receive this procedure. MATERIAL AND

METHODS:

We studied a historical cohort of 92 patients with COVID-19 and prolonged IMV (> 10 days). The primary outcome was the 90-day mortality rate. Secondary outcomes included days on IMV, hospital/intensive care unit (ICU) length of stay, frequency of nosocomial infections, and thrombotic complications demonstrated by images. A logistic regression was performed to adjust the effect of tracheostomy by SOFA score and days on IMV.

RESULTS:

Forty six patients aged 54 to 66 years (72% males) underwent tracheostomy. They had a median of two comorbidities, and received the procedure after a median of 20.5 days on IMV (interquartile range 17-26). 90-day mortality was lower in patients who were tracheostomized than in the control group (6.5% vs. 32.6%, p-value < 0.01). However, after controlling for confounding factors, no differences were found in mortality between both groups (relative risk = 0.303, p-value = 0.233). Healthcare-associated infections and hospital/ICU length of stay were higher in patients with tracheostomy than in controls. Thrombotic complications occurred in 42.4% of the patients, without differences between both groups. No cases of COVID-19 were registered in the healthcare personnel who performed tracheostomies.

CONCLUSIONS:

In patients with COVID-19 undergoing prolonged IMV, performing a tracheostomy is not associated with excess mortality, and it is a safe procedure for healthcare personnel.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Respiração Artificial / COVID-19 Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Rev Med Chil Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Respiração Artificial / COVID-19 Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Rev Med Chil Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile