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Lifestyle risk factors and all-cause and cause-specific mortality in the Mexico City prospective study: Assessing the influence of reverse causation.
Ferrari, Gerson; de Maio Nascimento, Marcelo; Petermann-Rocha, Fanny; Rezende, Leandro F M; O'Donovan, Gary; Gouveia, Élvio R; Cristi-Montero, Carlos; Marques, Adilson.
Afiliação
  • Ferrari G; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Providencia, Chile; Universidad de Santiago de Chile (USACH), Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, Santiago, Chile. Electronic address: gerson.demoraes@uautonoma.cl.
  • de Maio Nascimento M; Department of Physical Education, Federal University of Vale do São Francisco, Petrolina, Brazil.
  • Petermann-Rocha F; Centro de Investigación Biomédica, Facultad de Medicina, Universidad Diego Portales, Santiago, Chile.
  • Rezende LFM; Departamento de Medicina Preventiva, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
  • O'Donovan G; Instituto Masira, Universidad de Santander, Bucaramanga, Colombia; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez, Santiago, Chile; Facultad de Medicina, Universidad de los Andes, Bogotá, Colombia.
  • Gouveia ÉR; Department of Physical Education and Sport, University of Madeira, Funchal, Portugal; Laboratory of Robotics and Engineering Systems (LARSYS), Interactive Technologies Institute, Funchal, Portugal.
  • Cristi-Montero C; IRyS Group, Physical Education School, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
  • Marques A; CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Lisbon, Portugal; Faculdade de Medicina, ISAMB, Universidade de Lisboa, Lisbon, Portugal.
J Affect Disord ; 352: 517-524, 2024 May 01.
Article em En | MEDLINE | ID: mdl-38408614
ABSTRACT

BACKGROUND:

We examined the association between individual lifestyle risk factors with all-cause and cause-specific mortality.

METHODS:

Prospective cohort study including 155,002 participants from the Mexico City Prospective Study. Cox regression models were used to estimate the association between individual lifestyle risk factors and all-cause and cause-specific mortality. Participants with prevalent diseases at baseline and participants who died during the first 2, 5, 10, and 15 years of follow-up were excluded to account for reverse causation.

RESULTS:

27,469 people died during 18.3 years of follow-up years. Overweight and moderate alcohol consumption were inversely associated with all-cause mortality, while low physical activity and smoking were positively associated when all participants were included, regardless of prevalent disease or duration of follow-up. The direction of the association of overweight with all-cause mortality changed from inverse to positive after excluding the first 10 years of follow-up. Compared with normal weight, the hazard ratio (95 % confidence interval) was 1.17 (1.13,1.22) for obesity after excluding those who died in the first 5 years of follow-up and 1.71 (1.59,1.84) after excluding the first 15 years of follow-up. The magnitude of the association of alcohol intake, low physical activity, and smoking with mortality attenuated, whereas for fruits and vegetables increased, after excluding longer periods of follow-up.

LIMITATIONS:

The data were collected exclusively in Mexico City; lifestyle risk factors were self-reported and thus prone to misclassification bias.

CONCLUSIONS:

Reverse causation may influence both the magnitude and the direction of the associations between lifestyle risk factors and mortality.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sobrepeso / Estilo de Vida Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: J Affect Disord Ano de publicação: 2024 Tipo de documento: Article País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sobrepeso / Estilo de Vida Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: J Affect Disord Ano de publicação: 2024 Tipo de documento: Article País de publicação: Holanda