Your browser doesn't support javascript.
loading
Biogenic Ag2O nanoparticles with "Hoja Santa" (Piper auritum) extract: characterization and biological capabilities.
Aguilar-Ávila, Dalia S; Reyes-Becerril, M; Velázquez-Carriles, Carlos A; Hinojosa-Ventura, Gabriela; Macías-Rodríguez, María E; Angulo, Carlos; Silva-Jara, Jorge M.
Afiliação
  • Aguilar-Ávila DS; Chemical Engineering Department, Universidad de Guadalajara, CUCEI, Blvd. Marcelino García Barragán 1421, Olímpica, 44430, Guadalajara, Jalisco, Mexico.
  • Reyes-Becerril M; Immunology & Vaccinology Group, Centro de Investigaciones Biologicas del Noroeste (CIBNOR), Av. Instituto Politecnico Nacional 195, Playa Palo de Santa Rita Sur, 23096, La Paz, BCS, Mexico.
  • Velázquez-Carriles CA; Pharmacobiology Department, Universidad de Guadalajara, CUCEI, Blvd. Marcelino García Barragán 1421, Olímpica, 44430, Guadalajara, Jalisco, Mexico.
  • Hinojosa-Ventura G; Biological, Synthetic and Materials Engineering Department, Universidad de Guadalajara, CUTlajomulco, Carretera Tlajomulco - Santa Fé km 3.5, 595, Lomas de Tejeda, 45641, Tlajomulco de Zúñiga, Jalisco, Mexico.
  • Macías-Rodríguez ME; Chemical Engineering Department, Universidad de Guadalajara, CUCEI, Blvd. Marcelino García Barragán 1421, Olímpica, 44430, Guadalajara, Jalisco, Mexico.
  • Angulo C; Pharmacobiology Department, Universidad de Guadalajara, CUCEI, Blvd. Marcelino García Barragán 1421, Olímpica, 44430, Guadalajara, Jalisco, Mexico.
  • Silva-Jara JM; Immunology & Vaccinology Group, Centro de Investigaciones Biologicas del Noroeste (CIBNOR), Av. Instituto Politecnico Nacional 195, Playa Palo de Santa Rita Sur, 23096, La Paz, BCS, Mexico.
Biometals ; 37(4): 971-982, 2024 Aug.
Article em En | MEDLINE | ID: mdl-38409305
ABSTRACT
The 'sacred leaf' or "Hoja Santa" (Piper auritum Kunth) has a great value for Mexican culture and has gained popularity worldwide for its excellent properties from culinary to remedies. To contribute to its heritage, in this project we proposed the green synthesis of silver oxide nanoparticles (Ag2O NPs) using an extract of "Hoja Santa" (Piper auritum) as a reducing and stabilizing agent. The synthesized Ag2O NPs were characterized by UV-Visible spectroscopy (plasmon located at 405 nm), X-ray diffraction (XRD) (particle size diameter of 10 nm), scanning electron microscopy (SEM) (particle size diameter of 13.62 ± 4.61 nm), and Fourier-transform infrared spectroscopy (FTIR) (functional groups from "Hoja Santa" attached to nanoparticles). Antioxidant capacity was evaluated using DPPH, ABTS and FRAP methods. Furthermore, the antimicrobial activity of NPs against a panel of clinically relevant bacterial strains, including both Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Salmonella Enteritidis and Escherichia coli O157H7), was over 90% at concentrations of 200 µg/mL. Additionally, we assessed the antibiofilm activity of the NPs against Pseudomonas aeruginosa (reaching 98% of biofilm destruction at 800 µg/mL), as biofilm formation plays a crucial role in bacterial resistance and chronic infections. Moreover, we investigated the impact of Ag2O NPs on immune cell viability, respiratory burst, and phagocytic activity to understand their effects on the immune system.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Extratos Vegetais / Testes de Sensibilidade Microbiana / Compostos de Prata / Piper / Nanopartículas Metálicas / Antibacterianos Limite: Animals Idioma: En Revista: Biometals Assunto da revista: BIOQUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Extratos Vegetais / Testes de Sensibilidade Microbiana / Compostos de Prata / Piper / Nanopartículas Metálicas / Antibacterianos Limite: Animals Idioma: En Revista: Biometals Assunto da revista: BIOQUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Holanda