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Analysis of 26 STR loci (PowerPlex® Fusion 6C System) in a mestizo population from Mexico city.
López-Armenta, Mauro; Álvarez-Sánchez, María Elizbeth; León-Campos, Carolina; Gonzalez-Sobrino, Blanca Zoila; Rangel-Villalobos, Héctor; Muñoz-Valle, José Francisco; Sánchez-Méndez, Astrid Desireé; Aguilar-Velázquez, José Alonso.
Afiliação
  • López-Armenta M; Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Ciudad de México, México.
  • Álvarez-Sánchez ME; Instituto de Servicios Periciales y Ciencias Forenses (INCIFO), Poder Judicial de la Ciudad de México, Ciudad de México, México.
  • León-Campos C; Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Ciudad de México, México. maria.alvarez@uacm.edu.mx.
  • Gonzalez-Sobrino BZ; Instituto de Servicios Periciales y Ciencias Forenses (INCIFO), Poder Judicial de la Ciudad de México, Ciudad de México, México.
  • Rangel-Villalobos H; Instituto de Investigaciones Antropológicas, Universidad Nacional Autónoma de México, Ciudad de México, México.
  • Muñoz-Valle JF; Intituto de Investigación en Genética Molecular, Departamento de Ciencias Médicas y de la Vida, Centro Universitario de la Ciénega, Universidad de Guadalajara, Ocotlán, Jalisco, México.
  • Sánchez-Méndez AD; Instituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, México.
  • Aguilar-Velázquez JA; Laboratorio de Ciencias Morfológico Forenses y Medicina Molecular, Departamento de Morfología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, México.
Mol Biol Rep ; 51(1): 430, 2024 Mar 22.
Article em En | MEDLINE | ID: mdl-38517597
ABSTRACT

BACKGROUND:

Short tandem repeats (STRs) are the most widely used genetic markers in forensic genetics. Therefore, it is essential to document genetic population data of new kits designed for human identification purposes to enable laboratories to use these genetic systems to interpret and solve forensic casework. However, in Mexico, there are no studies with the PowerPlex Fusion 6C System, which includes 26 STRs (23 autosomal STRs and 3 Y-STRs). METHODS AND

RESULTS:

600 DNA samples from Mexico City were subjected to genotyping using the PowerPlex Fusion 6C System. For autosomal STRs, 312 different alleles were observed. Combined PE and PD were 99.999999809866% and 99.99999999999999999999999818795%, respectively. Genetic distances and AMOVA test showed low but significant differentiation between Mexican populations.

CONCLUSIONS:

The results reported in this work demonstrate the efficacy of this system for human identification purposes in the population studied and justify its possible application in other Mexican Mestizo populations.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Impressões Digitais de DNA / Genética Populacional Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: Mol Biol Rep Ano de publicação: 2024 Tipo de documento: Article País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Impressões Digitais de DNA / Genética Populacional Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: Mol Biol Rep Ano de publicação: 2024 Tipo de documento: Article País de publicação: Holanda