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A Descriptive Study of Corneal Graft Failure in Retransplant Patients.
Cruz, Giovanna Karinny Pereira; Júnior, Marcos Antonio Ferreira; Mota, Felipe Machado; Maidana, Gustavo Moura; Zulin, Maria Eduarda Gonçalves; Frota, Oleci Pereira; Santos, Viviane Euzébia Pereira; Vitor, Allyne Fortes.
Afiliação
  • Cruz GKP; Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
  • Júnior MAF; Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
  • Mota FM; Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil. Electronic address: felipemachadomota@gmail.com.
  • Maidana GM; Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
  • Zulin MEG; Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
  • Frota OP; Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
  • Santos VEP; Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
  • Vitor AF; Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Transplant Proc ; 56(5): 1129-1133, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38744590
ABSTRACT

OBJECTIVE:

To identify the main predictors for corneal graft failure in patients who underwent retransplantation.

METHOD:

This is a cross-sectional research with a quantitative and analytical approach, conducted based on data from secondary sources of a Human Eye Tissue Bank (HETB) in Northeast Brazil. Data were collected from the medical charts of all patients transplanted between January 2010 and December 2014. Descriptive statistics were used for the univariate analysis by means of absolute and relative frequencies and means. For the inferential analysis, the chi-square (X²) and the Fisher's Exact tests were used.

RESULTS:

A total of 241 records were reviewed, representing 258 keratoplasties, of which 27 (10.46%) were retransplantations due to corneal graft failure. Of the total, 55.56% of the individuals were female, with a mean age of 58.56 years, 55.56% of the population was brown, and the highest relative frequency of housing found was in the Central Mesoregion. Of the corneal graft failure cases, 88.89% were due to late failure, 30.77% of cases were classified as pseudophakic and 11.57% as aphakic. Through inferential analysis, a statistical association was obtained among the variable "corneal graft failure" and mesoregion of the state, presence of glaucoma, vascularization, and classification of the eye.

CONCLUSION:

The prognosis of keratoplasty is of multifactorial nature. Factors such as mesoregion of the State (place of residence), glaucoma, corneal vascularization, and aphakic eyes represent predictors for graft failure in the analyzed sample.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reoperação / Transplante de Córnea Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Transplant Proc Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reoperação / Transplante de Córnea Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Transplant Proc Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos